Functional differential equations arising in cell-growth

Non-local differential equations are notoriously difficult to solve. Cell-growth models for population growth of a cohort structured by size, simultaneously growing and dividing, give rise to a class of non-local eigenvalue problems, whose “principal” eigenvalue is the time-constant for growth/decay. These and other novel non-local problems are described and solved in special cases in this paper

Cryptococcal Meningitis Diagnostics and Screening in the Era of Point-of-Care Laboratory Testing.

Over the past ten years, standard diagnostics for cryptococcal meningitis in HIV-infected persons have evolved from culture to India ink to detection of cryptococcal antigen (CrAg), with the recent development and distribution of a point-of-care lateral flow assay. This assay is highly sensitive and specific in cerebrospinal fluid (CSF), but is also sensitive in the blood to detect CrAg prior to meningitis symptoms. CrAg screening of HIV-infected persons in the blood prior to development of fulminant meningitis and preemptive treatment for CrAg-positive persons are recommended by the World Health Organization and many national HIV guidelines. Thus, CrAg testing is occurring more widely, especially in resource-limited laboratory settings. CrAg titer predicts meningitis and death and could be used in the future to customize therapy according to burden of infection

Intellectual Growth For Undergraduate Students: Evaluation Results From An Undergraduate Research Conference

We describe the development and evaluation of the university-wide, weeklong undergraduate research conference at the University of New Hampshire. Despite increases nationally in the number of undergraduate research conferences (URC), there has been little research examining the social and educational impact of these events on student presenters. We describe the development and evaluation of the university-wide, weeklong URC at the University of New Hampshire. A survey administered to URC participants over a four year period revealed that research culminating in a presentation at the URC was one of the more influential events students experienced during their undergraduate years and students realized a high level of satisfaction from presenting at the URC

A simple model for predicting snow albedo decay using observations from the Community Collaborative Rain, Hail, and Snow-Albedo (CoCoRAHS-Albedo) Network

The albedo of seasonal snow cover plays an important role in the global climate system due to its influence on Earth’s radiation budget and energy balance. Volunteer CoCoRaHS-Albedo observers collected 3,249 individual daily albedo, snow depth, and density measurements using standardized techniques at dozens of sites across New Hampshire, USA over four winter seasons. The data show that albedo increases rapidly with snow depth up to ~ 0.14 m. Multiple linear regression models using snowpack age, snow depth or density, and air temperature provide reasonable approximations of surface snow albedo during times of albedo decay. However, the linear models also reveal systematic biases that highlight an important non-linearity in snow albedo decay. Modeled albedo values are reasonably accurate within the range of 0.6 to 0.9, but exhibit a tendency to over-estimate lower albedo values and under-estimate higher albedo values. We hypothesize that rapid reduction in high albedo fresh snow results from a decrease in snow specific surface area, while during melt-events the presence of liquid water in the snowpack accelerates metamorphism and grain growth. We conclude that the CoCoRaHS-Albedo volunteer observer network provides useful snow albedo, depth, and density measurements and serves as an effective model for future measurement campaigns

Evaluation of a doubly-swept blade tip for rotorcraft noise reduction

A computational study was performed for a doubly-swept rotor blade tip to determine its benefit for high-speed impulsive (HSI) and blade-vortex interaction (BVI) noise. This design consists of aft and forward sweep. For the HSI-noise computations, unsteady Euler calculations were performed for several variations to a rotor blade geometry. A doubly-swept planform was predicted to increase the delocalizing Mach number to 0.94 (representative of a 200+ kt helicopter). For the BVI-noise problem, it had been hypothesized that the doubly-swept blade tip, by producing a leading-edge vortex, would reduce the tip-vortex effect on BVI noise. A procedure was used in which the tip vortex velocity profile computed by a Navier-Stokes solver was used to compute the inflow associated with BVI. This inflow was used by a Euler solver to compute the unsteady pressures for an acoustic analysis. The results of this study were inconclusive due to the difficulty in accurately predicting the viscous tip vortex downstream of the blade. Also, for the condition studied, no leading-edge vortex formed at the tip

Evaluating the climate effects of mid-1800s deforestation in New England, USA, using a Weather, Research, and Forecasting (WRF) Model Multi-Physics Ensemble

The New England region of the northeastern United States has a land use history characterized by forest clearing for agriculture and other uses during European colonization and subsequent reforestation following widespread farm abandonment. Despite these broad changes, the potential influence on local and regional climate has received relatively little attention. This study investigated wintertime (December through March) climate impacts of reforestation in New England using a high-resolution (4 km) multiphysics ensemble of the Weather Research and Forecasting Model. In general, the conversion from mid-1800s cropland/grassland to forest led to warming, but results were sensitive to physics parameterizations. The 2-m maximum temperature (T2max) was most sensitive to choice of land surface model, 2-m minimum temperature (T2min) was sensitive to radiation scheme, and all ensemble members simulated precipitation poorly. Reforestation experiments suggest that conversion of mid-1800s cropland/grassland to present-day forest warmed T2max +0.5 to +3 K, with weaker warming during a warm, dry winter compared to a cold, snowy winter. Warmer T2max over forests was primarily the result of increased absorbed shortwave radiation and increased sensible heat flux compared to cropland/grassland. At night, T2min warmed +0.2 to +1.5 K where deciduous broadleaf forest replaced cropland/grassland, a result of decreased ground heat flux. By contrast, T2min of evergreen needleleaf forest cooled –0.5 to –2.1 K, primarily owing to increased ground heat flux and decreased sensible heat flux

The University of New Hampshire Engaged Scholars Academy: Instilling in Faculty Principles of Effective Partnership

Over the last decade, the University of New Hampshire (UNH) has promoted mutually beneficial partnerships between faculty and community partners vis-à-vis the Engaged Scholars Academy (ESA), a faculty development program aimed at enhancing faculty understanding of the principles of partnership and engaged scholarship. This research seeks to determine whether and how the ESA has impacted faculty-community partnerships around engaged scholarship. Findings suggest that Engaged Scholar Academy participants – as compared to non-participants – have a deeper understanding of the principles of partnership, are more likely to feel their scholarship is enhanced, spend more time with partners, engage their partners throughout the process of inquiry, and focus more on sustaining partnership outcomes

Palaeoecological Implications of Archaeological Seal Bone Assemblages: Case Studies from Labrador and Baffin Island

In recent years, increasing scientific attention has been paid to sea mammals as biological indicators of Arctic environmental change. The usefulness of animals such as ringed seal (Phoca hispida), harp seal (Phoca groenlandica), bearded seal (Erignathus barbatus), and harbour seal (Phoca vitulina) as indicator species is due to the close relationship of their range, reproductive cycles, and life histories to sea ice. The behaviour and distribution of these species correlate with ice conditions in the areas where the animals are encountered. The proportions of seal species represented in archaeological deposits may therefore reflect, at least in part, environmental conditions characterizing past seascapes. This paper examines zooarchaeological data from several Thule and historic Inuit archaeological sites in Baffin Island and Labrador, sites occupied during the last 700 years, to determine whether regional relationships can be demonstrated between subsistence economies, seal populations, and sea ice conditions. Ratios of ringed seal, harbour seal, bearded seal, and walrus (Odobenus rosmarus) bone frequencies from several archaeological sites are analyzed and discussed in light of new high-resolution proxy sea ice and regional palaeoenvironmental data. This exploratory study suggests that characteristics in seal species composition reflected in these assemblages can, in some circumstances, be correlated with recent sea ice reconstructions. However, a regional comparison of a larger number of more precisely dated archaeological sites is required for a full examination of these relationships. Au cours des dernières années, on a porté de plus en plus d'attention scientifique aux mammifères marins en tant qu'indicateurs biologiques du changement global dans l'Arctique. L'utilité d'animaux tels que le phoque annelé (Phoca hispida), le phoque du Groenland (Phoca groenlandica), le phoque barbu (Erignathus barbatus) et le phoque commun (Phoca vitulina) comme espèces indicatrices est due au rapport étroit que leurs aires de distribution, leurs cycles de reproduction et leurs cycles de vie ont avec la glace marine. Le comportement et la distribution de ces espèces sont corrélés avec les conditions de la glace dans les zones où l'on rencontre ces animaux. Les proportions des espèces de phoques qui se trouvent dans les dépôts archéologiques pourraient donc refléter, du moins partiellement, les conditions environnementales qui caractérisaient les paysages marins du passé. Cet article se penche sur les données zooarchéologiques provenant de plusieurs sites archéologiques Thulé et inuits dans l'île Baffin et le Labrador, sites occupés au cours des 700 dernières années, pour déterminer si l'on peut démontrer l'existence de rapports régionaux entre les économies de subsistance, les populations de phoques et les conditions de glace marine. Des taux de fréquence d'os de phoque annelé, de phoque commun, de phoque barbu et de morse provenant de plusieurs sites archéologiques font l'objet d'une analyse et d'une discussion à la lumière de nouvelles données indirectes à haute résolution sur la glace marine et sur le paléoenvironnement régional. Cette étude préliminaire suggère que les caractéristiques présentes dans la composition des espèces de phoques reflétée dans ces assemblages peuvent, dans certaines conditions, être corrélées aux reconstructions récentes de la glace marine. Une comparaison régionale d'un plus grand nombre de sites archéologiques datés de façon plus précise est toutefois nécessaire pour un examen exhaustif de ces rapports.

Palaeoecological Implications of Archaeological Seal Bone Assemblages: Case Studies from Labrador and Baffin Island

In recent years, increasing scientific attention has been paid to sea mammals as biological indicators of Arctic environmental change. The usefulness of animals such as ringed seal (Phoca hispida), harp seal (Phoca groenlandica), bearded seal (Erignathus barbatus), and harbour seal (Phoca vitulina) as indicator species is due to the close relationship of their range, reproductive cycles, and life histories to sea ice. The behaviour and distribution of these species correlate with ice conditions in the areas where the animals are encountered. The proportions of seal species represented in archaeological deposits may therefore reflect, at least in part, environmental conditions characterizing past seascapes. This paper examines zooarchaeological data from several Thule and historic Inuit archaeological sites in Baffin Island and Labrador, sites occupied during the last 700 years, to determine whether regional relationships can be demonstrated between subsistence economies, seal populations, and sea ice conditions. Ratios of ringed seal, harbour seal, bearded seal, and walrus (Odobenus rosmarus) bone frequencies from several archaeological sites are analyzed and discussed in light of new high-resolution proxy sea ice and regional palaeoenvironmental data. This exploratory study suggests that characteristics in seal species composition reflected in these assemblages can, in some circumstances, be correlated with recent sea ice reconstructions. However, a regional comparison of a larger number of more precisely dated archaeological sites is required for a full examination of these relationships. Au cours des dernières années, on a porté de plus en plus d'attention scientifique aux mammifères marins en tant qu'indicateurs biologiques du changement global dans l'Arctique. L'utilité d'animaux tels que le phoque annelé (Phoca hispida), le phoque du Groenland (Phoca groenlandica), le phoque barbu (Erignathus barbatus) et le phoque commun (Phoca vitulina) comme espèces indicatrices est due au rapport étroit que leurs aires de distribution, leurs cycles de reproduction et leurs cycles de vie ont avec la glace marine. Le comportement et la distribution de ces espèces sont corrélés avec les conditions de la glace dans les zones où l'on rencontre ces animaux. Les proportions des espèces de phoques qui se trouvent dans les dépôts archéologiques pourraient donc refléter, du moins partiellement, les conditions environnementales qui caractérisaient les paysages marins du passé. Cet article se penche sur les données zooarchéologiques provenant de plusieurs sites archéologiques Thulé et inuits dans l'île Baffin et le Labrador, sites occupés au cours des 700 dernières années, pour déterminer si l'on peut démontrer l'existence de rapports régionaux entre les économies de subsistance, les populations de phoques et les conditions de glace marine. Des taux de fréquence d'os de phoque annelé, de phoque commun, de phoque barbu et de morse provenant de plusieurs sites archéologiques font l'objet d'une analyse et d'une discussion à la lumière de nouvelles données indirectes à haute résolution sur la glace marine et sur le paléoenvironnement régional. Cette étude préliminaire suggère que les caractéristiques présentes dans la composition des espèces de phoques reflétée dans ces assemblages peuvent, dans certaines conditions, être corrélées aux reconstructions récentes de la glace marine. Une comparaison régionale d'un plus grand nombre de sites archéologiques datés de façon plus précise est toutefois nécessaire pour un examen exhaustif de ces rapports.