The Topical Problems of Regional Health Care in the Coverage of Omsk Media

In the modern world, one of the most urgent is the problem of health care, and the media are the leading conductors of medical and preventive knowledge in the field of health care to the general public. Purpose of the study: to reveal the problemthematic originality of materials devoted to health problems in the region, in the sociopolitical edition “Arguments and Facts in Omsk”. Research objectives: to study the role of the press in promoting public health problems; analyze media texts on regional health problems; to form an idea of the problem-thematic field of the healthcare sector as an urgent problem of the humanitarian agenda in the practice of modern Russian media; determine on the basis of monitoring and analysis “pain points” of Omsk healthcare. The object of the research is media texts published in the newspaper “AiF in Omsk”. The subject of the research is the problem-thematic originality of publications on health problems at the regional level. Empirical material — publications of the newspaper “AiF in Omsk” from 01.01.2017 to 01.05.2020. Research methods: content analysis, typological, comparative methods, method of statistical analysis.В современном мире одной из актуальнейших является проблема здравоохранения, а СМИ — ведущие проводники медицинских и профилактических знаний в области здравоохранения к широким слоям общественности. Цель исследования: выявить проблемно-тематическое своеобразие материалов, посвященных проблемам здравоохранения региона, в общественно-политическом издании «Аргументы и Факты в Омске». Исследовательские задачи: изучить роль прессы по продвижению в публичное пространство проблем здравоохранения; проанализировать медиатексты, посвященные проблемам регионального здравоохранения; сформировать представления о проблемно-тематическом поле сферы здравоохранения как актуальной проблеме гуманитарной повестки в практике современных российских СМИ; определить на основе мониторинга и анализа «болевые точки» омского здравоохранения. Объект исследования — медиатексты, опубликованные в газете «АиФ в Омске». Предмет исследования — проблемно-тематическое своеобразие публикаций о проблемах здравоохранения на региональном уровне. Эмпирический материал — публикации газеты «АиФ в Омске» с 01.01.2017 по 01.05.2020 гг. Методы исследования: контент-анализ, типологический, сравнительный методы, метод статистического анализа

Medical Periodicals of the Pre-Revolutionary Omsk: Thematic and Genre Uniqueness

Изучение региональной прессы Сибири в ее историко- функциональном развитии достаточно актуально на сегодняшний день. Омская пресса к. XIX — н. ХХ вв., в том числе специализированная, в сравнении с другими региональными изданиями, исследована недостаточно. Данным фактором объясняется актуальность работы. Объект исследования — «Протоколы Омского медицинского общества », «Врачебно-санитарная хроника города Омска». Предмет — жанрово-тематическая специфика и функциональное своеобразие омской дореволюционной медицинской периодики. Цель — выявить содержательное и жанровое своеобразие дореволюционной медицинской периодики Омска как административного центра Степного края. Для достижения поставленной цели необходимо выполнить ряд исследовательских задач: изучить историю организации системы здравоохранения Омска, в том числе и ее санитарной части; в ходе контент-анализа определить содержательную, жанровую и функциональную специфику анализируемых изданий. В работе были использованы несколько групп методов исследования: общенаучные, специально-исторические, специальные методы журналистского анализа. Эмпирическим материалом послужили выпуски «Протоколов Омского медицинского общества ». Хронологический период исследования — 1883–1911 гг.The study of the regional press of Siberia in its historical and functional development is quite relevant today. Omsk press in the end of XIX — beginning of XX centuries, including specialized one, in comparison with other regional publications has not been studied enough. This factor explains the relevance of the work. The object of the study is “Protocols of the Omsk Medical Society”, “Medical and sanitary chronicle of the city of Omsk”. The subject is the genre-thematic specificity and functional originality of Omsk pre-revolutionary medical periodicals. The goal is to reveal the content and genre originality of the pre-revolutionary medical periodicals of Omsk as the administrative center of the Steppe region. To achieve this goal, it is necessary to complete a number of research tasks: to study the history of the organization of the Omsk healthcare system, including its sanitary part; in the course of content analysis to determine the content, genre and functional specificity of the analyzed publications. Several groups of research methods were used in the work: general scientific, special-historical, special methods of journalistic analysis. Issues of the “Protocols of the Omsk Medical Society” served as empirical material. The chronological period of the study is 1883–1911

FinTech & New Digital Instruments. Post-Crisis Developments: Russia and Europe

The article examines 2020 post-crisis results and 2021 trends in FinTech regulation development. FinTech, being a relatively new term, has become a completely new industry, which combines rapidly developing technologies and financial products (including digital assets) or services. The year 2020, despite the pandemic and localization (and maybe even more so), seems as significant, if not more so, for market change and further development. The world has changed, and new technologies are vital for successful competition among financial players and even for their survival. Most of the leading international financial centers have focused on regulating FinTech and the use of innovations in classic highly regulated areas. In the article we address the pros and cons of technology regulation and make a comparative analysis of the leading revolutionary trends. The most revolutionary developments have appeared in smaller European countries, which the leaders are forced to follow. Law harmonization has become a natural step forward for Europe to regulate blockchain businesses and to agree on terminology and risk prevention measures for innovation support. The research examines the development and regulation of FinTech in such jurisdictions as Switzerland, Malta, Liechtenstein, Gibraltar and the United States. The approach is interdisciplinary, linking Russian legal norms, applicable rules, and expected results. The main methods used in the research are analysis, comparative-legal, and formal-legal methods

Spinal dural arteriovenous fistulas: Pathogenesis, clinical manifestations, diagnosis, treatment

The paper describes spinal dural arteriovenous fistulas (SDAVF), the most common type of spinal cord vascular anomalies. SDAVFs account for 60–80% of the spinal cord vascular anomalies. The causes of SDAVFs, the specific features of their hemodynamics, and their classification remain the subject matter of disputes.SDAVFs form in dura mater tissue, on the dorsal surface of radicular cuffs. The pathogenesis of neurological disorders in SDAVF has determined the name «venous hypertensive myelopathy», a spinal cord injury occurring in their presence. Pain and paresthesias, cacesthesia (more commonly in their distal parts), and motor disorders as flail legs are observed at the onset of SDAVF in typical cases. On average, 12 to 44 months elapse to establish its diagnosis. In addition of motor and sensory disorders, sphincter impairments and sexual dysfunction are detected in the patients at the time of diagnosis. By this time, most patients have already neurological disability.The paper presents the history of studying SDAVF, the existing classifications of arteriovenous malformations and fistulas, the clinical manifestations of venous hypertensive myelopathy in SDAVF, neuroimaging findings, and treatment options

Regression of lumbar disk herniation

Compression of the spinal nerve root, giving rise to pain and sensory and motor disorders in the area of its innervation is the most vivid manifestation of herniated intervertebral disk. Different treatment modalities, including neurosurgery, for evolving these conditions are discussed. There has been recent evidence that spontaneous regression of disk herniation can regress. The paper describes a female patient with large lateralized disc extrusion that has caused compression of the nerve root S1, leading to obvious myotonic and radicular syndrome. Magnetic resonance imaging has shown that the clinical manifestations of discogenic radiculopathy, as well myotonic syndrome and morphological changes completely regressed 8 months later. The likely mechanism is inflammation-induced resorption of a large herniated disk fragment, which agrees with the data available in the literature. A decision to perform neurosurgery for which the patient had indications was made during her first consultation. After regression of discogenic radiculopathy, there was only moderate pain caused by musculoskeletal diseases (facet syndrome, piriformis syndrome) that were successfully eliminated by minimally invasive techniques

Single-molecule techniques in biophysics : a review of the progress in methods and applications

Single-molecule biophysics has transformed our understanding of the fundamental molecular processes involved in living biological systems, but also of the fascinating physics of life. Far more exotic than a collection of exemplars of soft matter behaviour, active biological matter lives far from thermal equilibrium, and typically covers multiple length scales from the nanometre level of single molecules up several orders of magnitude to longer length scales in emergent structures of cells, tissues and organisms. Biological molecules are often characterized by an underlying instability, in that multiple metastable free energy states exist which are separated by energy levels of typically just a few multiples of the thermal energy scale of kBT, where kB is the Boltzmann constant and T the absolute temperature, implying complex, dynamic inter-conversion kinetics across this bumpy free energy landscape in the relatively hot, wet environment of real, living biological matter. The key utility of single-molecule biophysics lies in its ability to probe the underlying heterogeneity of free energy states across a population of molecules, which in general is too challenging for conventional ensemble level approaches which measure mean average properties. Parallel developments in both experimental and theoretical techniques have been key to the latest insights and are enabling the development of highly-multiplexed, correlative techniques to tackle previously intractable biological problems. Experimentally, technological developments in the sensitivity and speed of biomolecular detectors, the stability and efficiency of light sources, probes and microfluidics, have enabled and driven the study of heterogeneous behaviours both in vitro and in vivo that were previously undetectable by ensemble methods..

An Agent-Based Model of a Hepatic Inflammatory Response to Salmonella: A Computational Study under a Large Set of Experimental Data

Citation: Shi, Z. Z., Chapes, S. K., Ben-Arieh, D., & Wu, C. H. (2016). An Agent-Based Model of a Hepatic Inflammatory Response to Salmonella: A Computational Study under a Large Set of Experimental Data. Plos One, 11(8), 39. doi:10.1371/journal.pone.0161131We present an agent-based model (ABM) to simulate a hepatic inflammatory response (HIR) in a mouse infected by Salmonella that sometimes progressed to problematic proportions, known as "sepsis". Based on over 200 published studies, this ABM describes interactions among 21 cells or cytokines and incorporates 226 experimental data sets and/or data estimates from those reports to simulate a mouse HIR in silico. Our simulated results reproduced dynamic patterns of HIR reported in the literature. As shown in vivo, our model also demonstrated that sepsis was highly related to the initial Salmonella dose and the presence of components of the adaptive immune system. We determined that high mobility group box-1, C-reactive protein, and the interleukin-10: tumor necrosis factor-a ratio, and CD4+ T cell: CD8+ T cell ratio, all recognized as biomarkers during HIR, significantly correlated with outcomes of HIR. During therapy-directed silico simulations, our results demonstrated that anti-agent intervention impacted the survival rates of septic individuals in a time-dependent manner. By specifying the infected species, source of infection, and site of infection, this ABM enabled us to reproduce the kinetics of several essential indicators during a HIR, observe distinct dynamic patterns that are manifested during HIR, and allowed us to test proposed therapy-directed treatments. Although limitation still exists, this ABM is a step forward because it links underlying biological processes to computational simulation and was validated through a series of comparisons between the simulated results and experimental studies

The case of necrobiosis lipoidica in a child

The case of necrobiosis lipoidica in a girl of twelve is described. The clinical picture is presented by skin changes occurred on the patient's shins during 2 years. The changes on the shins are considered as post traumatic. Here there are some data about the pathogenesis, clinical forms and treatment

Staffing of agricultural organizations of Ryazan region in conditions of economy digitalization

The article presents the main problems of the introduction of digital technologies in agroindustrial complex. It is revealed that at present there is no single integrated solution for agricultural enterprises, which would integrate solutions for various branches of agriculture. It is substantiated that the task of creating a digital platform, with the help of which various digital solutions of specific business processes will be integrated, is a top priority. The tools for managing the digital transformation and innovation activities of the dairy industry enterprises and the platform solutions being created are considered on the example of Europe’s largest robotic animal husbandry complex in the dairy sector

ECONOMIC SCIENCES РАЗРАБОТКА КОМПЛЕКСА МЕР ДЛЯ ПОВЫШЕНИЯ РЕЗУЛЬТАТИВНОСТИ КОММЕРЧЕСКОГО ИСПОЛЬЗОВАНИЯ ИННОВАЦИОННОЙ СИСТЕМЫ СПЕКТРАЛЬНОЙ ОПТИЧЕСКОЙ КОГЕРЕНТНОЙ МИКРОСКОПИИ THE DEVELOPMENT OF COMPLEX MEASURES TO IMPROVE THE EFFICIENCY OF COMMERCIAL USE

В связи с активным развитием рынка научно-технической продукции актуальной проблемой стано-вится изыскание рациональных способов коммерциализации результатов научных разработок, в том числе и тех, которые изначально создавались как некоммерческие продукты. В статье авторы разрабатывают ме-ханизм вывода на рынок научно-технической разработки (системы оптической когерентной микроскопии (ОКМ)) с целью коммерческого использования, рассматривают и анализируют приемлемые формы коммер-циализации, формируют практические рекомендации, направленные на повышение результативности ком-мерческого использования системы ОКМ. Приведенная модель коммерциализации позволит в дальнейшем повысить перспективность новых исследований в данной области. Цель статьи заключается в разработке методических аспектов и практических рекомендаций по созданию и реализации комплекса мероприятий для повышения результативности коммерческого использования систем спектральной оптической когерент-ной микроскопии. Ключевые слова: коммерциализация, научно-техническая продукция, системы спектральной оптической когерентной микроскопии THE DEVELOPMENT OF COMPLEX MEASURES TO IMPROVE THE EFFICIENCY OF COMMERCIAL USE THE INNOVATION SYSTEM SPECTRAL OPTICAL COHERENT MICROSCOPY Tsukanova O.A., Shashkova E.V. Mechanics and Optics, St. Petersburg, e-mail: [email protected] In connection with active development of the market of scientifi c and technical products, the actual problem becomes the fi nding a rational ways of commercialization the results of scientifi c developments, including those which were originally created as a non-profi t products. In the article the authors develop a mechanism of a conclusion to the market of scientifi c and technical workings out (optical coherent microscopy (OCM)) with the purpose of commercial utilization, analyze acceptable forms of commercialization, form of practical recommendations aimed at improving the effi ciency of commercial use of the OCM. The model of commercialization will further enhance the prospects of new researches in this fi eld. The goal of this paper is to develop a methodological aspects and practical recommendations for creation and implementation of complex measures to improve the effi ciency of commercial use of the systems of spectral optical coherent microscopy. St. Petersburg National Research University of Information Technologies, Keywords: commercialization, scientifi c and technical products, systems spectral optical coherent microscopy В последние годы все большее значение во многих областях науки приобретает спек-тральная оптическая когерентная томография. Это высокоточный метод исследования, с по-мощью которого стало возможным получать изображение поперечного среза исследуемых биологических тканей с высокой разрешаю-щей способностью Коммерциализация представляет собой процесс разработки и реализации ряда ме-роприятий, с помощью которых результаты научных исследований и опытно-конструк-торских разработок можно предложить на рынках товаров и услуг с коммерческими целями [6]. Использование систем ОКМ с целью получения прибыли может иметь место в различных отраслях медицины, в области материаловедения и диагностики старинных предметов искусства. Одним из разработчиков новых систем ОКМ является НИУ ИТМО, где ведутся ис-следования в области создания нового оп-тического когерентного микроскопа. При этом в настоящее время коммерциализация результатов научной деятельности явля-ется одним из направлений деятельности университета. Для результативной коммер-циализации научно-технической разработ-ки необходимо создать четкий механизм трансфера технологии. Коммерциализация системы спектраль-ной ОКМ может быть осуществлена по схе-ме, представленной на рисунке