Stability of the Horizontal Curvature of the LHC Cryodipoles During Cold Tests

The LHC will be composed of 1232 horizontally curved, 15 meter long, superconducting dipole magnets cooled at 1.9 K. They are supported within their vacuum vessel by three Glass Fiber Reinforced Epoxy (GFRE) support posts. Each cryodipole is individually cold tested at CERN before its installation and interconnection in the LHC 27 km circumference tunnel. As the magnet geometry under cryogenic operation is extremely important for the LHC machine aperture, a new method has been developed at CERN in order to monitor the magnet curvature change between warm and cold states. It enabled us to conclude that there is no permanent horizontal curvature change of the LHC dipole magnet between warm and cold states, although a systematic horizontal transient deformation during cool-down was detected. This deformation generates loads in the dipole supporting system; further investigation permitted us to infer this behavior to the asymmetric thermal contraction of the rigid magnet thermal shield during cool-down. Controlling the helium flow rate in the thermal shield of the cryomagnet enabled us to reduce the maximal deformation by a factor of approximately two, thus increasing significantly the mechanical safety margin of the supporting system during the CERN cold tests

Forage Yield and Nutritive Value of 30 Cultivars of Maize for Silage in the Highland Valleys of Central Mexico

In Mexico, the selection of maize cultivars for forage has mainly been based on dry matter (DM) yields, not considering nutritional quality as an important evaluation parameter. The objective of this study was to assess forage yield and nutritive value of Highland and Subtropical maize cultivars for silage in the Highland Valleys of Central México

Antagonistic Interaction of Staphylococcus aureus Toward Candida glabrata During in vitro Biofilm Formation Is Caused by an Apoptotic Mechanism

Background: Infections caused by Candida species and Staphylococcus aureus are associated with biofilm formation. C. albicans–S. aureus interactions are synergistic due to the significant increase in mixed biofilms and improved resistance to vancomycin of S. aureus. C. glabrata and S. aureus both are nosocomial pathogens that cause opportunistic infections in similar host niches. However, there is scarce information concerning the interaction between these last microorganisms.Results: The relationship between C. glabrata and S. aureus was evaluated by estimating the viability of both microorganisms in co-culture of planktonic cells and in single and mixed biofilms. An antagonistic behavior of S. aureus and their cell-free bacterial supernatant (CFBS) toward C. glabrata, both in planktonic form and in biofilms, was demonstrated. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), and confocal laser scanning microscopy (CLSM) images showed yeast cells surrounded by bacteria, alterations in intracytoplasmic membranes, and non-viable blastoconidia with intact cell walls. Concomitantly, S. aureus cells remained viable and unaltered. The antagonistic activity of S. aureus toward C. glabrata was not due to cell-to-cell contact but the presence of CFBS, which causes a significant decrement in yeast viability and the formation of numerous lipid droplets (LDs), reactive oxygen species (ROS) accumulation, as well as nuclear alterations, and DNA fragmentation indicating the induction of an apoptotic mechanism.Conclusion: Our results demonstrate that the S. aureus CFBS causes cell death in C. glabrata by an apoptotic mechanism

Guillain-Barré syndrome following the 2009 pandemic monovalent and seasonal trivalent influenza vaccination campaigns in Spain from 2009 to 2011: Outcomes from active surveillance by a neurologist network, and records from a country-wide hospital discharge database

Background: Studies have shown a slight excess risk in Guillain-Barré syndrome (GBS) incidence associated with A(H1N1)pdm09 vaccination campaign and seasonal trivalent influenza vaccine immunisations in 2009-2010. We aimed to assess the incidence of GBS as a potential adverse effect of A(H1N1)pdm09 vaccination. Methods: A neurologist-led network, active at the neurology departments of ten general hospitals serving an adult population of 4.68 million, conducted GBS surveillance in Spain in 2009-2011. The network, established in 1996, carried out a retrospective and a prospective study to estimate monthly alarm thresholds in GBS incidence and tested them in 1998-1999 in a pilot study. Such incidence thresholds additionally to observation of GBS cases with immunisation antecedent in the 42 days prior to clinical onset were taken as alarm signals for 2009-2011, since November 2009 onwards. For purpose of surveillance, in 2009 we updated both the available centres and the populations served by the network. We also did a retrospective countrywide review of hospital-discharged patients having ICD-9-CM code 357.0 (acute infective polyneuritis) as their principal diagnosis from January 2009 to December 2011. Results: Among 141 confirmed of 148 notified cases of GBS or Miller-Fisher syndrome, Brighton 1-2 criteria in 96 %, not a single patient was identified with clinical onset during the 42-day time interval following A(H1N1)pdm09 vaccination. In contrast, seven cases were seen during a similar period after seasonal campaigns. Monthly incidence figures did not, however, exceed the upper 95 % CI limit of expected incidence. A retrospective countrywide review of the registry of hospital-discharged patients having ICD-9-CM code 357.0 (acute infective polyneuritis) as their principal diagnosis did not suggest higher admission rates in critical months across the period December 2009-February 2010. Conclusions: Despite limited power and underlying reporting bias in 2010-2011, an increase in GBS incidence over background GBS, associated with A(H1N1)pdm09 monovalent or trivalent influenza immunisations, appears unlikely

Psicoterapia y problemas actuales. Debates y alternativas

Ante la proliferación de fenómenos psicosociales, como el suicidio, la violencia sexual, los trastornos del comportamiento alimenticio y las crisis de identidad, emerge esta obra, como una respuesta reflexiva que aborda desde una pluralidad de perspectivas el quehacer psicoterapéutico, para favorecer una comprensión amplia de estas situaciones problema y ofrecer, desde la experiencia de sus autores, alternativas de entendimiento y de desarrollo de tratamientos para la atención de quienes las viven. El objetivo es compartir una comprensión innovadora de la práctica del psicoterapeuta, desde una mirada caracterizada por el diálogo interdisciplinario. Ello a partir de la recuperación de las estrategias implementadas frente a distintas coyunturas, así como a través de la reflexión personal en torno a la formación y el ejercicio profesional del psicoterapeuta, que pueden favorecer la retroalimentación y la generación de formas de intervención más adecuadas a la realidad de algunos dilemas contemporáneos y de los entornos en que estos se desenvuelven. Un libro recomendable para estudiantes, docentes y profesionales en el campo de la psicoterapia y la salud psicosocial.ITESO. A.C

Resumen ejecutivo del Documento de Consenso de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC) y de la Asociación Española de Cirujanos (AEC) en profilaxis antibiótica en cirugía

La profilaxis antibiótica en cirugía es una de las medidas más eficaces para la prevención de la infección de localización quirúrgica, aunque su uso es con frecuencia inadecuado, pudiendo incrementar el riesgo de infección, toxicidades y resistencias bacterianas. Debido al avance en las técnicas quirúrgicas y la emergencia de microorganismos multirresistentes las actuales pautas de profilaxis precisan ser revisadas. La Sociedad Española de Enfermedades Infecciosas (SEIMC), conjuntamente con la Asociación Española de Cirujanos (AEC) ha revisado y actualizado las recomendaciones de profilaxis antimicrobiana para adaptarlas a cada tipo de intervención quirúrgica y a la epidemiología actual. En este documento se recogen las recomendaciones de los antimicrobianos utilizados en profilaxis en los diferentes procedimientos, las dosis, la duración, la profilaxis en huéspedes especiales, y en situación epidemiológica de multirresistencia, de tal forma que permitan un manejo estandarizado, un uso racional, seguro y efectivo de los mismos en la cirugía electiva. Antibiotic prophylaxis in surgery is one of the most effective measures for preventing surgical site infection, although its use is frequently inadequate and may even increase the risk of infection, toxicities and antimicrobial resistance. As a result of advances in surgical techniques and the emergence of multidrug-resistant organisms, the current guidelines for prophylaxis need to be revised. The Sociedad Española de Enfermedades Infecciosas (Spanish Society of Infectious Diseases and Clinical Microbiology) (SEIMC) together with the Asociación Española de Cirujanos (Spanish Association of Surgeons) (AEC) have revised and updated the recommendations for antibiotic prophylaxis in surgery to adapt them to any type of surgical intervention and to current epidemiology. This document gathers together the recommendations on antimicrobial prophylaxis in the various procedures, with doses, duration, prophylaxis in special patient groups, and in epidemiological settings of multidrug resistance to facilitate standardized management and the safe, effective and rational use of antibiotics in elective surgery

Contourite depositional system after the exit of a strait: Case study from the late Miocene South Rifian Corridor, Morocco

Idealized facies of bottom current deposits (contourites) have been established for fine-grained contourite drifts in modern deep-marine sedimentary environments. Their equivalent facies in the ancient record however are only scarcely recognized due to the weathered nature of most fine-grained deposits in outcrop. Facies related to the erosional elements (i.e. contourite channels) of contourite depositional systems have not yet been properly established and related deposits in outcrop appear non-existent. To better understand the sedimentary facies and facies sequences of contourites, the upper Miocene contourite depositional systems of the South Rifian Corridor (Morocco) is investigated. This contourite depositional system formed by the dense palaeo-Mediterranean Outflow Water. Foraminifera assemblages were used for age-constraints (7.51 to 7.35 Ma) and to determine the continental slope depositional domains. Nine sedimentary facies have been recognized based on lithology, grain-size, sedimentary structures and biogenic structures. These facies were subsequently grouped into five facies associations related to the main interpreted depositional processes (hemipelagic settling, contour currents and gravity flows). The vertical sedimentary facies succession records the tectonically induced, southward migration of the contourite depositional systems and the intermittent behaviour of the palaeo-Mediterranean Outflow Water, which is mainly driven by precession and millennial-scale climate variations. Tides substantially modulated the palaeo-Mediterranean Outflow Water on a sub-annual scale. This work shows exceptional examples of muddy and sandy contourite deposits in outcrop by which a facies distribution model from the proximal continental slope, the contourite channel to its adjacent contourite drift, is proposed. This model serves as a reference for contourite recognition both in modern environments and the ancient record. Furthermore, by establishing the hydrodynamics of overflow behaviour a framework is provided that improves process-based interpretation of deep-water bottom current deposits

Anales de Edafología y Agrobiología Tomo 36 Número 1-2

Duración efectiva del índice de sequedad, por M. P. Garmendía y J. Garmendía.-- Adsorción y evolución de manganeso en arcillas, por O. Carpena, I. Tovar, A. Lax y F. Costa.-- Ecología de leguminosas en relación con algunos factores ambientales en Guadalajara. I. Aspectos florísticos y relación con la clase ele suelo, por M. Morey.-- Variaciones del contenido de nitrógeno en una plantación de Lolium perenne,por Esther Simón Martínez.-- Predicción de temperaturas máximas diarias, por E. Hernández, J. A. Hernández, J. F. Sánchez y J. Garmendía.-- Efectos del almacenaje sobre las propiedades físicas y biológicas de muestras tamizadas de suelos orgánicos, por F. Díaz-Fierros Viqueiro.-- Morfometría del cuarzo y circón aplicada al estudio genético de un suelo policíclico, por M. C. Villar Celorio.-- Contribución al estudio de la terra rossa española. II. Mineralogía de la fracción arcilla, por L. J. Alías, M. Nieto y J. Albaladejo.-- Entisoles del Campo de Cartagena (Murcia). Características generales y mineralógicas, por L. J. Alías y R. Ortiz Silla.-- Estudio sobre la composición química de variedades de almendra del sureste español, por F. Romojaro, J. F. García y F. J. López Andreu.-- Componentes del plátano canario y sus variaciones durante la maduración, por A. Carlos Blesa, M. A. Rodríguez Raymond y A. Maestre.-- Contribución al estudio de la platanera canaria. Relación entre la actividad respiratoria y la maduración de los plátanos, por A. Carlos Blesa, M. A Rodríguez Raymoud, C. D. Lorenzo e Isabel López.-- Notas.-- Reestructuración del C. S. I. C.-- Nombramiento del Prof. Casas Peláez como Presidente del C. S. I. C. 1.-- Carta del Presidente del C. S. I. C. al personal del mismo.-- Nombramiento del Prof. Snárez y Suárez como Director general de Educación Bastea.-- 6.° Curso Internacional de Fertilidad de Suelos y Nutrición Vegetal.—8ª Reunión Internacional de Micromorfología de Suelos.—19ª Conferencia General de la UNESCO.-- Sociedad Española de Ciencia del Suelo.-- Nombramiento de Secretario del Centro de Edafología y Biología Aplicada de Salamanca.-- Dimisión del Director del Centre de Edafología y Biología Aplicada del Cuarto (Sevilla).-- Propuesta de Director del Centro de Edafología y Biología Aplicada del Cuarto.-- Viaje del Prof. Troncoso.-- Grupo Español de Trabajo del Cuaternario.-- Autorizaciones para realizar función docente.-- Invitaciones a Profesores extranjeros.-- Programa de cooperación internacional con lberoamérica: bolsas de estudio y viaje .-- Conferencia del Prof. Salerno.-- Viaje realizado a Hispanoamérica por el Dr. D. Francisco Girela Vilchez.-- Creación del Centro de Formaci.ón y Promoción de Personal del C. S. I. C. (C. F. P. P.)Peer reviewed2019-08.- CopyBook.- Libnova.- Biblioteca ICA

The European Solar Telescope

The European Solar Telescope (EST) is a project aimed at studying the magnetic connectivity of the solar atmosphere, from the deep photosphere to the upper chromosphere. Its design combines the knowledge and expertise gathered by the European solar physics community during the construction and operation of state-of-the-art solar telescopes operating in visible and near-infrared wavelengths: the Swedish 1m Solar Telescope, the German Vacuum Tower Telescope and GREGOR, the French Télescope Héliographique pour l'Étude du Magnétisme et des Instabilités Solaires, and the Dutch Open Telescope. With its 4.2 m primary mirror and an open configuration, EST will become the most powerful European ground-based facility to study the Sun in the coming decades in the visible and near-infrared bands. EST uses the most innovative technological advances: the first adaptive secondary mirror ever used in a solar telescope, a complex multi-conjugate adaptive optics with deformable mirrors that form part of the optical design in a natural way, a polarimetrically compensated telescope design that eliminates the complex temporal variation and wavelength dependence of the telescope Mueller matrix, and an instrument suite containing several (etalon-based) tunable imaging spectropolarimeters and several integral field unit spectropolarimeters. This publication summarises some fundamental science questions that can be addressed with the telescope, together with a complete description of its major subsystems