10,391 research outputs found
Prospects for measuring the electric dipole moment of the electron using electrically trapped polar molecules
Heavy polar molecules can be used to measure the electric dipole moment of
the electron, which is a sensitive probe of physics beyond the Standard Model.
The value is determined by measuring the precession of the molecule's spin in a
plane perpendicular to an applied electric field. The longer this precession
evolves coherently, the higher the precision of the measurement. For molecules
in a trap, this coherence time could be very long indeed. We evaluate the
sensitivity of an experiment where neutral molecules are trapped electrically,
and compare this to an equivalent measurement in a molecular beam. We consider
the use of a Stark decelerator to load the trap from a supersonic source, and
calculate the deceleration efficiency for YbF molecules in both strong-field
seeking and weak-field seeking states. With a 1s holding time in the trap, the
statistical sensitivity could be ten times higher than it is in the beam
experiment, and this could improve by a further factor of five if the trap can
be loaded from a source of larger emittance. We study some effects due to field
inhomogeneity in the trap and find that rotation of the electric field
direction, leading to an inhomogeneous geometric phase shift, is the primary
obstacle to a sensitive trap-based measurement.Comment: 22 pages, 7 figures, prepared for Faraday Discussion 14
Stochastic multi-channel lock-in detection
High-precision measurements benefit from lock-in detection of small signals.
Here we discuss the extension of lock-in detection to many channels, using
mutually orthogonal modulation waveforms, and show how the the choice of
waveforms affects the information content of the signal. We also consider how
well the detection scheme rejects noise, both random and correlated. We address
the particular difficulty of rejecting a background drift that makes a
reproducible offset in the output signal and we show how a systematic error can
be avoided by changing the waveforms between runs and averaging over many runs.
These advances made possible a recent measurement of the electron's electric
dipole moment.Comment: 11 pages, 3 figure
Evaluation of anomalies observed on film from S-190A flight system calibration test
Due to a persistent problem of scratched film from testing of the Skylab S-190A system, a series of tests were designed to identify the cause of the film scratching. The procedures followed in this test for pretest handling and packaging of the film, the makeup of the rolls for processing, and the results of the processed film evaluation are reported
Pulsed beams as field probes for precision measurement
We describe a technique for mapping the spatial variation of static electric,
static magnetic, and rf magnetic fields using a pulsed atomic or molecular
beam. The method is demonstrated using a beam designed to measure the electric
dipole moment of the electron. We present maps of the interaction region,
showing sensitivity to (i) electric field variation of 1.5 V/cm at 3.3 kV/cm
with a spatial resolution of 15 mm; (ii) magnetic field variation of 5 nT with
25 mm resolution; (iii) radio-frequency magnetic field amplitude with 15 mm
resolution. This new diagnostic technique is very powerful in the context of
high-precision atomic and molecular physics experiments, where pulsed beams
have not hitherto found widespread application.Comment: 6 pages, 12 figures. Figures heavily compressed to comply with
arxiv's antediluvian file-size polic
Franck-Condon Factors and Radiative Lifetime of the A^{2}\Pi_{1/2} - X^{2}\Sigma^{+} Transition of Ytterbium Monoflouride, YbF
The fluorescence spectrum resulting from laser excitation of the
A^{2}\Pi_{1/2} - X^{2}\Sigma^{+} (0,0) band of ytterbium monofluoride, YbF, has
been recorded and analyzed to determine the Franck-Condon factors. The measured
values are compared with those predicted from Rydberg-Klein-Rees (RKR)
potential energy curves. From the fluorescence decay curve the radiative
lifetime of the A^{2}\Pi_{1/2} state is measured to be 28\pm2 ns, and the
corresponding transition dipole moment is 4.39\pm0.16 D. The implications for
laser cooling YbF are discussed.Comment: 5 pages, 5 figure
Interplanetary Trajectory Optimization with Powerlimited Propulsion Systems
A trajectory-optimization process is described in which the optimum thrust equations are derived using the calculus of variations. The magnitude of the thrust is constrained within an upper and a lower bound, but the thrust direction is arbitrary. This formulation allows both the constant-thrust program and the variable-thrust program to be considered. For the constant-thrust program, certain propulsion-system parameters are optimized for maximum final vehicle mass. This theory has been used to study interplanetary missions to Venus and Mars using a power-limited propulsion system. Both one-way and round trip rendezvous trajectories are considered. The analysis employs a two-body inverse-square force-field model of three dimensions. An iterative routine used to solve the two-point boundary-value problem is described in the Appendix
Augmented Sparse Reconstruction of Protein Signaling Networks
The problem of reconstructing and identifying intracellular protein signaling
and biochemical networks is of critical importance in biology today. We sought
to develop a mathematical approach to this problem using, as a test case, one
of the most well-studied and clinically important signaling networks in biology
today, the epidermal growth factor receptor (EGFR) driven signaling cascade.
More specifically, we suggest a method, augmented sparse reconstruction, for
the identification of links among nodes of ordinary differential equation (ODE)
networks from a small set of trajectories with different initial conditions.
Our method builds a system of representation by using a collection of integrals
of all given trajectories and by attenuating block of terms in the
representation itself. The system of representation is then augmented with
random vectors, and minimization of the 1-norm is used to find sparse
representations for the dynamical interactions of each node. Augmentation by
random vectors is crucial, since sparsity alone is not able to handle the large
error-in-variables in the representation. Augmented sparse reconstruction
allows to consider potentially very large spaces of models and it is able to
detect with high accuracy the few relevant links among nodes, even when
moderate noise is added to the measured trajectories. After showing the
performance of our method on a model of the EGFR protein network, we sketch
briefly the potential future therapeutic applications of this approach.Comment: 24 pages, 6 figure
Unraveling the molecular basis of subunit specificity in P pilus assembly by mass spectrometry
P pili are multisubunit fibers essential for the attachment of uropathogenic Escherichia coli to the kidney. These fibers are formed by the noncovalent assembly of six different homologous subunit types in an array that is strictly defined in terms of both the number and order of each subunit type. Assembly occurs through a mechanism termed “donor-strand exchange (DSE)” in which an N-terminal extension (Nte) of one subunit donates a β-strand to an adjacent subunit, completing its Ig fold. Despite structural determination of the different subunits, the mechanism determining specificity of subunit ordering in pilus assembly remained unclear. Here, we have used noncovalent mass spectrometry to monitor DSE between all 30 possible pairs of P pilus subunits and their Ntes. We demonstrate a striking correlation between the natural order of subunits in pili and their ability to undergo DSE in vitro. The results reveal insights into the molecular mechanism by which subunit ordering during the assembly of this complex is achieved
Iodine sorption study on the proposed use of Viton A in a shuttle galley water accumulator
The installation of a Viton A accumulator in the Shuttle galley has been proposed to prevent overpressurization of the hot water supply system. A laboratory study has been conducted to determine if there would be any interaction between the Viton A material and the iodine used to disinfect the water. Coupons of Viton A were exposed for 24 hours to aqueous iodine solutions similar in quality to the Shuttle's potable water. Changes in the iodine residual were monitored to determine the rate of iodine sorption by the coupon. Total organic carbon (TOC) was monitored to determine the rate of desorption of organic materials from the Viton A. The same coupons were then soaked in reagent-grade water for 24 hours, and iodine was monitored to determine the rate of iodine desorption. The coupons were again exposed to iodine solutions for 24 hours and iodine and TOC were monitored. No significant change in the iodine sorption rate was detected between the first and second exposures. A triangle taste test indicated at a 1 percent confidence level that the water exposed to Viton A had a different taste which was less acceptable to the panelists
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