2,729 research outputs found

    Dynamic Model Derivation of a 3RRR Robot Based in Screw Theory

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    In this article a technique to obtain a dynamic model of a 3RRR robot from its kinematic model based on screw theory is proposed, which allows to obtain the open or closed robot kinematics. First the kinematic model is obtained in a compact form and then the dynamic model is obtained from the Euler Lagrange method, with this the simplicity and compactness characteristics are transferred to the dynamic model. The dynamic model is obtained initially for the actuated joints and then for the effector coordinates through its interrelations. To prove the effectiveness of this theoretical derivation the obtained model is tested with a proportional-derivative controller (PD) because it provides a simple control strategy that can be extended later to more effective controllers

    Enzymatic extraction of hydroxycinnamic acids from coffee pulp

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    Ferulic, caffeic, p-coumaric and chlorogenic acids are classified as hydroxycinnamic acids, presenting anticarcinogenic, anti-inflammatory and antioxidant properties. In this work, enzymatic extraction has been studied in order to extract high value-added products like hydroxycinnamic acids from coffee pulp. A commercial pectinase and enzyme extract produced by Rhizomucor pusillus strain 23aIV in solid-state fermentation using olive oil or coffee pulp (CP) as an inducer of the feruloyl esterase activity were evaluated separately and mixed. The total content (covalently linked and free) of ferulic, caffeic, p-coumaric and chlorogenic acids was 5276 mg per kg of coffee pulp. Distribution was as follows (in %): chlorogenic acid 58.7, caffeic acid 37.6, ferulic acid 2.1 and p-coumaric acid 1.5. Most of the hydroxycinnamic acids were covalently bound to the cell wall (in %): p-coumaric acid 97.2, caffeic acid 94.4, chlorogenic acid 76.9 and ferulic acid 73.4. The content of covalently linked hydroxycinnamic acid was used to calculate the enzyme extraction yield. The maximum carbon dioxide rate for the solid-state fermentation using olive oil as an inducer was higher and it was reached in a short cultivation time. Nevertheless, the feruloyl esterase (FAE) activity (units per mg of protein) obtained in the fermentation using CP as an inducer was 31.8 % higher in comparison with that obtained in the fermentation using olive oil as the inducer. To our knowledge, this is the first report indicating the composition of both esterified and free ferulic, caffeic, p-coumaric and chlorogenic acids in coffee pulp. The highest yield of extraction of hydroxycinnamic acids was obtained by mixing the produced enzyme extract using coffee pulp as an inducer and a commercial pectinase. Extraction yields were as follows (in %): chlorogenic acid 54.4, ferulic acid 19.8, p-coumaric acid 7.2 and caffeic acid 2.3. An important increase in the added value of coffee pulp was mainly due to the extraction of chlorogenic acid

    Real-time Soundprism

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    [EN] This paper presents a parallel real-time sound source separation system for decomposing an audio signal captured with a single microphone in so many audio signals as the number of instruments that are really playing. This approach is usually known as Soundprism. The application scenario of the system is for a concert hall in which users, instead of listening to the mixed audio, want to receive the audio of just an instrument, focusing on a particular performance. The challenge is even greater since we are interested in a real-time system on handheld devices, i.e., devices characterized by both low power consumption and mobility. The results presented show that it is possible to obtain real-time results in the tested scenarios using an ARM processor aided by a GPU, when this one is present.This work has been supported by the "Ministerio de Economia y Competitividad" of Spain and FEDER under projects TEC2015-67387-C4-{1,2,3}-R.Muñoz-Montoro, AJ.; Ranilla, J.; Vera-Candeas, P.; Combarro, EF.; Alonso-Jordá, P. (2019). Real-time Soundprism. The Journal of Supercomputing. 75(3):1594-1609. https://doi.org/10.1007/s11227-018-2703-0S15941609753Alonso P, Cortina R, Rodríguez-Serrano FJ, Vera-Candeas P, Alonso-González M, Ranilla J (2017) Parallel online time warping for real-time audio-to-score alignment in multi-core systems. J Supercomput 73:126. https://doi.org/10.1007/s11227-016-1647-5Carabias-Orti JJ, Cobos M, Vera-Candeas P, Rodríguez-Serrano FJ (2013) Nonnegative signal factorization with learnt instrument models for sound source separation in close-microphone recordings. EURASIP J Adv Signal Process 2013:184. https://doi.org/10.1186/1687-6180-2013-184Carabias-Orti JJ, Rodriguez-Serrano FJ, Vera-Candeas P, Canadas-Quesada FJ, Ruiz-Reyes N (2015) An audio to score alignment framework using spectral factorization and dynamic time warping. In: 16th International Society for Music Information Retrieval Conference, pp 742–748Díaz-Gracia N, Cocaña-Fernández A, Alonso-González M, Martínez-Zaldívar FJ, Cortina R, García-Mollá VM, Alonso P, Ranilla J (2014) NNMFPACK: a versatile approach to an NNMF parallel library. In: Proceedings of the 2014 International Conference on Computational and Mathematical Methods in Science and Engineering, pp 456–465Díaz-Gracia N, Cocaña-Fernández A, Alonso-González M, Martínez-Zaldívar FJ, Cortina R, García-Mollá VM, Vidal AM (2015) Improving NNMFPACK with heterogeneous and efficient kernels for β\beta β -divergence metrics. J Supercomput 71:1846–1856. https://doi.org/10.1007/s11227-014-1363-yDriedger J, Grohganz H, Prätzlich T, Ewert S, Müller M (2013) Score-informed audio decomposition and applications. In: Proceedings of the 21st ACM International Conference on Multimedia, pp 541–544Duan Z, Pardo B (2011) Soundprism: an online system for score-informed source separation of music audio. IEEE J Sel Top Signal Process 5(6):1205–1215Duong NQ, Vincent E, Gribonval R (2010) Under-determined reverberant audio source separation using a full-rank spatial covariance model. IEEE Trans Audio Speech 18(7):1830–1840. https://doi.org/10.1109/TASL.2010.2050716Ewert S, Müller M (2011) Estimating note intensities in music recordings. In: Proceedings of the IEEE International Conference on Acoustics, Speech, and Signal Processing, pp 385–388Ewert S, Pardo B, Mueller M, Plumbley MD (2014) Score-informed source separation for musical audio recordings: an overview. IEEE Signal Process Mag 31:116–124. https://doi.org/10.1109/MSP.2013.2296076Fastl H, Zwicker E (2007) Psychoacoustics. Springer, BerlinGanseman J, Scheunders P, Mysore GJ, Abel JS (2010) Source separation by score synthesis. Int Comput Music Conf 2010:1–4Goto M, Hashiguchi H, Nishimura T, Oka R (2002) RWC music database: popular, classical and jazz music databases. In: ISMIR, vol 2, pp 287–288Goto M (2004) Development of the RWC music database. In: Proceedings of the 18th International Congress on Acoustics (ICA 2004), ppp 553–556Hennequin R, David B, Badeau R (2011) Score informed audio source separation using a parametric model of non-negative spectrogram. In: 2011 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP) pp 45–48. https://doi.org/10.1109/ICASSP.2011.5946324Itoyama K, Goto M, Komatani K et al (2008) Instrument equalizer for query-by-example retrieval: improving sound source separation based on integrated harmonic and inharmonic models. In: ISMIR. https://doi.org/10.1136/bmj.324.7341.827Marxer R, Janer J, Bonada J (2012) Low-latency instrument separation in polyphonic audio using timbre models. In: International Conference on Latent Variable Analysis and Signal Separation, pp 314–321Miron M, Carabias-Orti JJ, Janer J (2015) Improving score-informed source separation for classical music through note refinement. In: ISMIR, pp 448–454Ozerov A, Févotte C (2010) Multichannel nonnegative matrix factorization in convolutive mixtures for audio source separation. IEEE Trans Audio Speech Lang Process 18:550–563. https://doi.org/10.1109/TASL.2009.2031510Ozerov A, Vincent E, Bimbot F (2012) A general flexible framework for the handling of prior information in audio source separation. IEEE Trans Audio Speech Lang Process 20:1118–1133. https://doi.org/10.1109/TASL.2011.2172425Pätynen J, Pulkki V, Lokki T (2008) Anechoic recording system for symphony orchestra. Acta Acust United Acust 94:856–865. https://doi.org/10.3813/AAA.918104Raphael C (2008) A classifier-based approach to score-guided source separation of musical audio. Comput Music J 32:51–59. https://doi.org/10.1162/comj.2008.32.1.51Rodriguez-Serrano FJ, Duan Z, Vera-Candeas P, Pardo B, Carabias-Orti JJ (2015) Online score-informed source separation with adaptive instrument models. J New Music Res 44:83–96. https://doi.org/10.1080/09298215.2014.989174Rodriguez-Serrano FJ, Carabias-Orti JJ, Vera-Candeas P, Martinez-Munoz D (2016) Tempo driven audio-to-score alignment using spectral decomposition and online dynamic time warping. ACM Trans Intell Syst Technol 8:1–20. https://doi.org/10.1145/2926717Sawada H, Araki S, Makino S (2011) Underdetermined convolutive blind source separation via frequency bin-wise clustering and permutation alignment. IEEE Trans Audio Speech Lang Process 19(3):516–527. https://doi.org/10.1109/TASL.2010.2051355Vincent E, Araki S, Theis F et al (2012) The signal separation evaluation campaign (2007–2010): achievements and remaining challenges. Signal Process 92:1928–1936. https://doi.org/10.1016/j.sigpro.2011.10.007Vincent E, Bertin N, Gribonval R, Bimbot F (2014) From blind to guided audio source separation: how models and side information can improve the separation of sound. IEEE Signal Process Mag 31:107–115. https://doi.org/10.1109/MSP.2013.229744

    Characterization of Mycobacterium tuberculosis Beijing isolates from the Mediterranean area

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    <p>Abstract</p> <p>Background</p> <p>The Beijing lineage of <it>Mycobacterium tuberculosis </it>is causing concern due to its global distribution and its involvement in severe outbreaks. Studies focused on this lineage are mainly restricted to geographical settings where its prevalence is high, whereas those in other areas are scarce. In this study, we analyze Beijing isolates in the Mediterranean area, where this lineage is not prevalent and is mainly associated with immigrant cases.</p> <p>Results</p> <p>Only 1% (N = 26) of the isolates from two population-based studies in Spain corresponded to Beijing strains, most of which were pan-susceptible and from Peruvian and Ecuadorian patients. Restriction fragment length polymorphism typing with the insertion sequence IS<it>6110 </it>identified three small clusters (2-3 cases). Mycobacterial interspersed repetitive unit-variable number tandem repeat typing (MIRU-15) offered low discriminatory power, requiring the introduction of five additional loci. A selection of the Beijing isolates identified in the Spanish sample, together with a sample of Beijing strains from Italy, to broaden the analysis context in the Mediterranean area, were assayed in an infection model with THP-1 cells. A wide range of intracellular growth rates was observed with only two isolates showing an increased intracellular replication, in both cases associated with contained production of TNF-α. No correlation was observed between virulence and the Beijing phylogenetic group, clustered/orphan status, or resistance. The Beijing strain responsible for extensive spread on Gran Canaria Island was also identified in Madrid, but did not lead to secondary cases and did not show high infectivity in the infection model.</p> <p>Conclusions</p> <p>The Beijing lineage in our area is a non-homogeneous family, with only certain highly virulent representatives. The specific characterization of Beijing isolates in different settings could help us to accurately identify the virulent representatives before making general assumptions about this lineage.</p
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