Body dissatisfaction, internalized weight bias and quality of life in young men and women

Purpose:We examined the relative importance of body dissatisfaction (BD) and internalized weight bias (IWB) in accounting for variance in quality of life (QoL) impairment in an ethnically diverse sample of college students (n = 630) and potential moderation of these associations by sex.Methods:Participants completed an online survey that included established measures of BD, IWB and QoL. Regression models were used to examine the relative contributions of BD and IWB in accounting for variance in physical and mental QoL impairment.Results:BD and IWB were highly correlated with bivariate analysis in both women (r = .76) and men (r = .60). In multivariable analysis, IWB was found to be associated with both physical (b = − 1.33, 95% CI − 1.93, − 0.72) and mental (b = − 2.58, 95% CI − 3.45, − 1.72) QoL impairment, whilst BD was not associated with impairment in either physical (b = − 0.29, 95% CI − 0.68, 0.09) or mental (b = − 0.48, 95% CI − 1.03, 0.07) QoL. While levels of both BD and IWB were higher for women than for men, sex did not moderate the association between either BD or IWB and either physical or mental QoL.Conclusions:The findings support the view that IWB warrants greater attention in interventions seeking to reduce the adverse impact of BD in both women and men and both normal-weight and overweight individuals

Age-related memory impairment associated with loss of parietal deactivation but preserved hippocampal activation

The neural underpinnings of age-related memory impairment remain to be fully elucidated. Using a subsequent memory face–name functional MRI (fMRI) paradigm, young and old adults showed a similar magnitude and extent of hippocampal activation during successful associative encoding. Young adults demonstrated greater deactivation (task-induced decrease in BOLD signal) in medial parietal regions during successful compared with failed encoding, whereas old adults as a group did not demonstrate a differential pattern of deactivation between trial types. The failure of deactivation was particularly evident in old adults who performed poorly on the memory task. These low-performing old adults demonstrated greater hippocampal and prefrontal activation to achieve successful encoding trials, possibly as a compensatory response. Findings suggest that successful encoding requires the coordination of neural activity in hippocampal, prefrontal, and parietal regions, and that age-related memory impairment may be primarily related to a loss of deactivation in medial parietal regions