Does input trade liberalization boost downstream firms’ exports? Theory and firm-level evidence

We analyze the impact of input tariffs on the export status and export performance of heterogeneous processing firms. Using a theoretical model with downstream firms exhibiting different levels of productivity, we show that lower input tariffs may increase the export sales of high-productivity firms at the expense of low-productivity firms and may decrease the probability of firms entering foreign markets. We compare the predictions of the theoretical model with firm-level data from the French agrifood sector by developing a two-stage estimation procedure that uses an equation for selection into export markets in the first stage and an exports equation in the second stage. The liberalization of agricultural trade appears to favor the reallocation of market share from low- to high-productivity agrifood firms. In addition, our results suggest that, whether lower input tariffs increase total exports sales (and jobs), a large fraction of the least productive exporting firms may lose from an additional decrease in agricultural input tariffs

Limits on Low Energy Photon-Photon Scattering from an Experiment on Magnetic Vacuum Birefringence

Experimental bounds on induced vacuum magnetic birefringence can be used to improve present photon-photon scattering limits in the electronvolt energy range. Measurements with the PVLAS apparatus (E. Zavattini {\it et al.}, Phys. Rev. D {\bf77} (2008) 032006) at both $\lambda = 1064$ nm and 532 nm lead to bounds on the parameter {\it A$_{e}$}, describing non linear effects in QED, of $A_{e}^{(1064)} < 6.6\cdot10^{-21}$ T$^{-2}$ @ 1064 nm and $A_{e}^{(532)} < 6.3\cdot10^{-21}$ T$^{-2}$ @ 532 nm, respectively, at 95% confidence level, compared to the predicted value of $A_{e}=1.32\cdot10^{-24}$ T$^{-2}$. The total photon-photon scattering cross section may also be expressed in terms of $A_e$, setting bounds for unpolarized light of $\sigma_{\gamma\gamma}^{(1064)} < 4.6\cdot10^{-62}$ m$^{2}$ and $\sigma_{\gamma\gamma}^{(532)} < 2.7\cdot10^{-60}$ m$^{2}$. Compared to the expected QED scattering cross section these results are a factor of $\simeq2\cdot10^{7}$ higher and represent an improvement of a factor about 500 on previous bounds based on ellipticity measurements and of a factor of about $10^{10}$ on bounds based on direct stimulated scattering measurements

New PVLAS results and limits on magnetically induced optical rotation and ellipticity in vacuum

IIn 2006 the PVLAS collaboration reported the observation of an optical rotation generated in vacuum by a magnetic field. To further check against possible instrumental artifacts several upgrades to the PVLAS apparatus have been made during the last year. Two data taking runs, at the wavelength of 1064 nm, have been performed in the new configuration with magnetic field strengths of 2.3 T and 5 T. The 2.3 T field value was chosen in order to avoid stray fields. The new observations do not show the presence of a rotation signal down to the levels of $1.2\cdot 10^{-8}$ rad at 5 T and $1.0\cdot 10^{-8}$ rad at 2.3 T (at 95% c.l.) with 45000 passes in the magnetic field zone. In the same conditions no ellipticity signal was detected down to $1.4\cdot 10^{-8}$ at 2.3 T (at 95% c.l.), whereas at 5 T a signal is still present. The physical nature of this ellipticity as due to an effect depending on $B^2$ can be excluded by the measurement at 2.3 T. These new results completely exclude the previously published magnetically induced vacuum dichroism results, indicating that they were instrumental artifacts. These new results therefore also exclude the particle interpretation of the previous PVLAS results as due to a spin zero boson. The background ellipticity at 2.3 T can be used to determine a new limit on the total photon-photon scattering cross section of $\sigma_{\gamma\gamma} < 4.5 \cdot10^{-34}$ barn at 95% c.l..Comment: 25 pages, 7 figures Main changes rel. to v.2: minor changes to abstract, replaced Figures 4,5,6, corrected typographical errors. Paper submitted to Physical Review

requirements for naive CD4+ T cell stimulation

Human primary dendritic cells (DCs) are heterogeneous by phenotype, function, and tissue localization and distinct from inflammatory monocyte-derived DCs. Current information regarding the susceptibility and functional role of primary human DC subsets to Mycobacterium tuberculosis (Mtb) infection is limited. Here, we dissect the response of different primary DC subsets to Mtb infection. Myeloid CD11c+ cells and pDCs (C-type lectin 4C+ cells) were located in human lymph nodes (LNs) of tuberculosis (TB) patients by histochemistry. Rare CD141hi DCs (C-type lectin 9A+ cells) were also identified. Infection with live Mtb revealed a higher responsiveness of myeloid CD1c+ DCs compared to CD141hi DCs and pDCs. CD1c+ DCs produced interleukin (IL)-6, tumor necrosis factor α, and IL-1β but not IL-12p70, a cytokine important for Th1 activation and host defenses against Mtb. Yet, CD1c+ DCs were able to activate autologous naïve CD4+ T cells. By combining cell purification with fluorescence-activated cell sorting and gene expression profiling on rare cell populations, we detected in responding CD4+ T cells, genes related to effector-cytolytic functions and transcription factors associated with Th1, Th17, and Treg polarization, suggesting multifunctional properties in our experimental conditions. Finally, immunohistologic analyses revealed contact between CD11c+ cells and pDCs in LNs of TB patients and in vitro data suggest that cooperation between Mtb-infected CD1c+ DCs and pDCs favors stimulation of CD4+ T cells

Advanced Differentiated Thyroid Cancer. A Complex Condition Needing a Tailored Approach

Differentiated thyroid cancers (DTCs) are slow-growing malignant tumours, including papillary and follicular carcinomas. Overall, prognosis is good, although it tends to worsen when local invasion occurs with bulky cervical nodes, or in the case of distant metastases. Surgery represents the main treatment for DTCs. However, radical excision is challenging and significant morbidity and functional loss can follow the treatment of the more advanced forms. Literature on advanced thyroid tumours, both differentiated and undifferentiated, does not provide clear and specific guidelines. This emerges the need for a tailored and multidisciplinary approach. In the present study, we report our single-centre experience of 111 advanced (local, regional, and distant) DTCs, investigating the rate of radical excision, peri-procedural and post-procedural complications, quality of life, persistence, recurrence rates, and survival rates. Results are critically appraised and compared to the existing published evidence review

Comparison of the LUNA 3He(alpha,gamma)7Be activation results with earlier measurements and model calculations

Recently, the LUNA collaboration has carried out a high precision measurement on the 3He(alpha,gamma)7Be reaction cross section with both activation and on-line gamma-detection methods at unprecedented low energies. In this paper the results obtained with the activation method are summarized. The results are compared with previous activation experiments and the zero energy extrapolated astrophysical S factor is determined using different theoretical models.Comment: Accepted for publication in Journal of Physics

Activation measurement of the 3He(alpha,gamma)7Be cross section at low energy

The nuclear physics input from the 3He(alpha,gamma)7Be cross section is a major uncertainty in the fluxes of 7Be and 8B neutrinos from the Sun predicted by solar models and in the 7Li abundance obtained in big-bang nucleosynthesis calculations. The present work reports on a new precision experiment using the activation technique at energies directly relevant to big-bang nucleosynthesis. Previously such low energies had been reached experimentally only by the prompt-gamma technique and with inferior precision. Using a windowless gas target, high beam intensity and low background gamma-counting facilities, the 3He(alpha,gamma)7Be cross section has been determined at 127, 148 and 169 keV center-of-mass energy with a total uncertainty of 4%. The sources of systematic uncertainty are discussed in detail. The present data can be used in big-bang nucleosynthesis calculations and to constrain the extrapolation of the 3He(alpha,gamma)7Be astrophysical S-factor to solar energies

The 3He(alpha,gamma)7Be S-factor at solar energies: the prompt gamma experiment at LUNA

The 3He(alpha,gamma)7Be process is a key reaction in both Big-Bang nucleosynthesis and p-p chain of Hydrogen Burning in Stars. A new measurement of the 3He(alpha,gamma)7Be cross section has been performed at the INFN Gran Sasso underground laboratory by both the activation and the prompt gamma detection methods. The present work reports full details of the prompt gamma detection experiment, focusing on the determination of the systematic uncertainty. The final data, including activation measurements at LUNA, are compared with the results of the last generation experiments and two different theoretical models are used to obtain the S-factor at solar energies.Comment: Accepted for publication in Nucl. Phys.