5,915 research outputs found

    Flutter: A finite element program for aerodynamic instability analysis of general shells of revolution with thermal prestress

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    Documentation for the computer program FLUTTER is presented. The theory of aerodynamic instability with thermal prestress is discussed. Theoretical aspects of the finite element matrices required in the aerodynamic instability analysis are also discussed. General organization of the computer program is explained, and instructions are then presented for the execution of the program

    Mineral fabrication and golgi apparatus activity in the mouse calvarium

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    There is diverse opinion about the mechanism of bone mineralization with only intermittent reports of any direct organellar role played by the golgi apparatus (juxtanuclear body). Light and laser confocal microscopy was combined with electron microscopy and elemental EDX (energy dispersive X-ray microanalysis) in comparing ā€œyoungā€ osteocytes in situ in fresh and ā€œslamā€ frozen developing mouse calvarium, with similar cells (MC3T3-E1) maintained in vitro. The distribution of ā€œnascentā€ electron dense mineral was examined histochemically (von Kossa, GBHA), including tetracycline (TC) staining as a fluorescent complex with bone salt, while golgi body activity was demonstrated by transfection with a specific green fluorescent construct (GFP/mannosidase II). In tissue culture golgi body activity and mineralization were both blocked by brefeldin A (an established golgi inhibitor) and restored by forskolin, enabling an association with mineral fabrication to be quantified as changing fluorescence intensity (AU) of GFP or TC markers. Results from osteocytes in situ supported previous descriptions of intracellular electron dense objects (microspheres and nanospheres) in a juxtanuclear pattern, containing Ca, P and transitory Si, in a spectrum recapitulated in the calcifying culture after 10 days, when GFP fluorophore surged from 71.7 Ā± 1.4SD to 133.7 Ā± 2.7SD AU by 14 days (p < 0.0001). At this stage TC fluorophore mean intensity was 23.8 Ā± 3.7SD AU (14 days) rising to 45.0 Ā± 5.1SD AU by 17 days, compared to its stationary 21.7 Ā± 3.6SD when treated 3 days previously with BFA golgi inhibitor (p < 0.0001), until forskolin reversal. It was concluded from the changing juxtanuclear morphology, Si mineralization mediation and the variably controlled activity versus stasis that the inorganic phase of bone is a complex golgi-directed fabrication with implications for bone matrix biology and evolution

    A Comparative Analysis of Depolarization Strategies

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    The salience of political polarization has increased rapidly in the last few years as this phenomenon has infiltrated countries across the globe, including the United States. A potential consequence of polarization is democratic decay, or the gradual transition of democracies into more autocratic regimes. Remedies proposed by scholars include electoral system reforms, inclusive rhetorical strategies, and civic dialogue initiatives, among others. This thesis investigates institutional and political remedies, relying on both quantitative and qualitative analyses, to determine whether these approaches to depolarization are effective in practice. The findings are applied to the US case

    Common Benefit Fees in Multidistrict Litigation

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    Two Results in Drawing Graphs on Surfaces

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    In this work we present results on crossing-critical graphs drawn on non-planar surfaces and results on edge-hamiltonicity of graphs on the Klein bottle. We first give an infinite family of graphs that are 2-crossing-critical on the projective plane. Using this result, we construct 2-crossing-critical graphs for each non-orientable surface. Next, we use 2-amalgamations to construct 2-crossing-critical graphs for each orientable surface other than the sphere. Finally, we contribute to the pursuit of characterizing 4-connected graphs that embed on the Klein bottle and fail to be edge-hamiltonian. We show that known 4-connected counterexamples to edge-hamiltonicity on the Klein bottle are hamiltonian and their structure allows restoration of edge-hamiltonicity with only a small change

    Holocene-Neogene volcanism in northeastern Australia: chronology and eruption history

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    Quaternary and late Neogene volcanism is widespread in northeastern Australia, producing at least 397 eruptions covering more than 20,000 km2, including at least 20 flows over 50 km long. Despite this abundance of young volcanism, before this study numerous eruptions had tentative ages or were undated, and the area requires a comprehensive evaluation of eruption patterns through time. To help address these issues we applied multi-collector ARGUS-V 40Ar/39Ar geochronology to determine the age of four of the younger extensive flows: Undara (160 km long, 189 Ā± 4/4 ka; 2Ļƒ, with full analytical/external uncertainties), Murronga (40 km long, 153 Ā± 5/5 ka), Toomba (120 km long, 21 Ā± 3/3 ka), and Kinrara (55 km long, 7 Ā± 2/2 ka). Verbal traditions of the Gugu Badhun Aboriginal people contain features that may potentially describe the eruption of Kinrara. If the traditions do record this eruption, they would have been passed down for 230 Ā± 70 generations ā€“ a period of time exceeding the earliest written historical records. To further examine north Queensland volcanism through time we compiled a database of 337 ages, including 179 previously unpublished K-Ar and radiocarbon results. The compiled ages demonstrate that volcanic activity has occurred without major time breaks since at least 9 Ma. The greatest frequency of eruptions occurred in the last 2 Ma, with an average recurrence interval of <10ā€“22 ka between eruptions. Activity was at times likely more frequent than these calculations indicate, as the geochronologic dataset is incomplete, with undated eruptions, and intraplate volcanism is often episodic. The duration, frequency, and youthfulness of activity indicate that north Queensland volcanism should be considered as potentially still active, and there are now two confirmed areas of Holocene volcanism in eastern Australia ā€“ one at each end of the continent. More broadly, our data provides another example of 40Ar/39Ar geochronology applied to Holocene and latest Pleistocene mafic eruptions, further demonstrating that this method has the ability to examine eruptions and hazards at the youngest volcanoes on Earth

    West Virginia\u27s Pioneer Women Lawyers

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    Body Composition Measurement in Children with Cerebral Palsy, Spina Bifida and Spinal Cord Injury: A Systematic Review of the Literature

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    Pediatric obesity is a major health concern that has an increased prevalence in children with special needs. In order to categorize a childā€™s weight, an assessment of body composition is needed. Obtaining an accurate body composition measurement in children with special needs has many challenges associated with it. This perplexing scenario limits the providerā€™s ability to screen, prevent and treat an abnormal weight status in this vulnerable population. This systematic review summarizes common methods of body composition measurements, their strengths and limitations and reviews the literature when measurements were used in children with cerebral palsy, spina bifida and spinal cord injury. Following PRISMA guidelines, 222 studies were identified. The application of the inclusion and exclusion criteria yielded a final sample of nine studies included in this review. Overall, articles reinforced the inconsistencies of body composition measurement and methodology when used with children with special needs. Concerns include small sample sizes, the need to validate prediction equations for this population, and the lack of controlled trials and reporting of measurement methodology. Healthcare providers need to be aware of the complexities associated with measuring body composition in children with special needs and advocate for further testing of these measurements. Additional studies addressing the reliability and validity of these measures are needed to facilitate appropriate health promotion in children

    Experimental evaluation of mobile phone sensors

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    Smart phone has become an important part of people's daily life. Most of current smart phone are equipped with a rich set of built-in sensors. The mobile applications such as geo-location based video annotation and indoor positioning require precise measurements from sensors. In addition, understanding the sensing performance of a smart phone device is helpful for implementing a mobile application that needs sensor data. This paper presents an experimental evaluation of key sensors in a state of the art smart phone - Google Nexus 4. The sensors chosen in the paper are accelerometer, gyroscope, magnetometer and GPS. Substantial tests have been executed to evaluate the sensors' accuracy, precision, maximum sampling frequency, sampling period jitter, energy consumption
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