1,119 research outputs found
Nuclear magnetic resonance measurements reveal the origin of the Debye process in monohydroxy alcohols
Monohydroxy alcohols show a structural relaxation and at longer time scales a
Debye-type dielectric peak. From spin-lattice relaxation experiments using
different nuclear probes an intermediate, slower-than-structural dynamics is
identified for n-butanol. Based on these findings and on diffusion
measurements, a model of self-restructuring, transient chains is proposed. The
model is demonstrated to explain consistently the so far puzzling observations
made for this class of hydrogen-bonded glass forming liquids.Comment: 4 pages, 4 figure
Low-Density Granulocytes Are a Novel Immunopathological Feature in Both Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder
Objective: To investigate whether low-density granulocytes (LDGs) are an immunophenotypic feature of patients with multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD).
Methods: Blood samples were collected from 20 patients with NMOSD and 17 patients with MS, as well as from 15 patients with Systemic Lupus Erythematosus (SLE) and 23 Healthy Donors (HD). We isolated peripheral blood mononuclear cells (PBMCs) with density gradient separation and stained the cells with antibodies against CD14, CD15, CD16, and CD45, and analyzed the cells by flow cytometry or imaging flow cytometry. We defined LDGs as CD14-CD15(high) and calculated their share in total PBMC leukocytes (CD45+) as well as the share of CD16(hi) LDGs. Clinical data on disease course, medication, and antibody status were obtained.
Results: LDGs were significantly more common in MS and NMOSD than in HDs, comparable to SLE samples (median values HD 0.2%, MS 0.9%, NMOSD 2.1%, SLE 4.3%). 0/23 of the HDs, but 17/20 NMOSD and 11/17 MS samples as well as 13/15 SLE samples had at least 0.7 % LDGs. NMOSD patients without continuous immunosuppressive treatment had significantly more LDGs compared to their treated counterparts. LDG nuclear morphology ranged from segmented to rounded, suggesting a heterogeneity within the group.
Conclusion: LDGs are a feature of the immunophenotype in some patients with MS and NMOSD
Classical and Quantum Gravity in 1+1 Dimensions, Part I: A Unifying Approach
We provide a concise approach to generalized dilaton theories with and
without torsion and coupling to Yang-Mills fields. Transformations on the space
of fields are used to trivialize the field equations locally. In this way their
solution becomes accessible within a few lines of calculation only. In this
first of a series of papers we set the stage for a thorough global
investigation of classical and quantum aspects of more or less all available 2D
gravity-Yang-Mills models.Comment: 24 pages, no figures, some sign errors in Eqs. 52--59 have been
corrected (according to the Erratum
Two-dimensional interactions between a BF-type theory and a collection of vector fields
Consistent interactions that can be added to a two-dimensional, free abelian
gauge theory comprising a special class of BF-type models and a collection of
vector fields are constructed from the deformation of the solution to the
master equation based on specific cohomological techniques. The deformation
procedure modifies the Lagrangian action, the gauge transformations, as well as
the accompanying algebra of the interacting model.Comment: LaTeX 2e, 31 page
2d Gauge Theories and Generalized Geometry
We show that in the context of two-dimensional sigma models minimal coupling
of an ordinary rigid symmetry Lie algebra leads naturally to the
appearance of the "generalized tangent bundle" by means of composite fields. Gauge transformations of the composite
fields follow the Courant bracket, closing upon the choice of a Dirac structure
(or, more generally, the choide of a "small
Dirac-Rinehart sheaf" ), in which the fields as well as the symmetry
parameters are to take values. In these new variables, the gauge theory takes
the form of a (non-topological) Dirac sigma model, which is applicable in a
more general context and proves to be universal in two space-time dimensions: A
gauging of of a standard sigma model with Wess-Zumino term
exists, \emph{iff} there is a prolongation of the rigid symmetry to a Lie
algebroid morphism from the action Lie algebroid
into (or the algebraic analogue of the morphism in the case of
). The gauged sigma model results from a pullback by this morphism
from the Dirac sigma model, which proves to be universal in two-spacetime
dimensions in this sense.Comment: 22 pages, 2 figures; To appear in Journal of High Energy Physic
Ca2+-calmodulin-dependent modification of smooth-muscle myosin light-chain kinase leading to its co-operative activation by calmodulin
String-Inspired Gravity Coupled to Yang-Mills Fields
String-inspired 1+1-dimensional gravity is coupled to Yang-Mills fields in
the Cangemi-Jackiw gauge-theoretical formulation, based on the extended
Poincar\'e group. A family of couplings, which involves metrics obtainable from
the physical metric with a conformal rescaling, is considered, and the
resulting family of models is investigated both at the classical and the
quantum level. In particular, also using a series of Kirillov-Kostant phases,
the wave functionals that solve the constraints are identified.Comment: 15 pages, LaTex
Anharmonic Evolution of the Cosmic Axion Density Spectrum
We present analytic solutions to the spatially homogeneous axion field
equation, using a model potential which strongly resembles the standard
anharmonic potential, but contains only a piece-wise second
order term. Our exactly soluble model for spans the entire range
. In particular, we are able to confirm (i) Turner's numeric
correction factors \cite{Turner} to the adiabatic and harmonic analytic
treatments of homogeneous axion oscillations, and (ii) Lyth's estimate
\cite{Lyth} valid near the metastable misalignment angle at the peak of
the potential. We compute the enhancement of axion density fluctuations that
occurs when the axion mass becomes significant at GeV. We find that
the anharmonicity amplifies density \mbox{f}luctuations, but only significantly
for relatively large initial misalignment angles. The enhancement factor is
(2,3,4,13) for .Comment: 26 pages, 6 figures appended as a ps-file, Latex, DAMTP-94-21,
VAND-TH-94-
Functional Schroedinger and BRST Quantization of (1+1)--Dimensional Gravity
We discuss the quantization of pure string--inspired dilaton--gravity in
--dimensions, and of the same theory coupled to scalar matter. We
perform the quantization using the functional Schroedinger and BRST formalisms.
We find, both for pure gravity and the matter--coupled theory, that the two
quantization procedures give inequivalent ``physical'' results.Comment: 40 pages, Late
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