Breastfeeding and Breast Cancer Risk Bibliography

Bibliography on breastfeeding and the risk of breast cancerBibliography on breastfeeding and the risk of breast cancer. Includes review articles, human studies, studies on breast cancer incidence in breast-fed babies, other resource materials, and articles on the chemical contamination of breast milk.United States Department of Agriculture CSREES, and the New York State Department of Healt

"D'ogni legge nemico e d'ogni fede"

In un verso di Ariosto, la sorte di Giordano Bruno. SPECIALE V CENTENARIO ORLANDO FURIOSO (1516–2016

In vivo and in vitro evidence that intrinsic upper- and lower-limb skeletal muscle function is unaffected by ageing and disuse in oldest-old humans

Aim: To parse out the impact of advanced ageing and disuse on skeletal muscle function, we utilized both in vivo and in vitro techniques to comprehensively assess upper- and lower-limb muscle contractile properties in 8 young (YG; 25 6 years) and 8 oldest-old mobile (OM; 87 5 years) and 8 immobile (OI; 88 4 years) women. Methods: In vivo, maximal voluntary contraction (MVC), electrically evoked resting twitch force (RT), and physiological cross-sectional area (PCSA) of the quadriceps and elbow flexors were assessed. Muscle biopsies of the vastus lateralis and biceps brachii facilitated the in vitro assessment of single fibre-specific tension (Po). Results: In vivo, compared to the young, both the OM and OI exhibited a more pronounced loss of MVC in the lower limb [OM (60%) and OI (75%)] than the upper limb (OM = 51%; OI = 47%). Taking into account the reduction in muscle PCSA (OM = 10%; OI = 18%), only evident in the lower limb, by calculating voluntary muscle-specific force, the lower limb of the OI (40%) was more compromised than the OM (13%). However, in vivo, RT in both upper and lower limbs (approx. 9.8 N m cm 2) and Po (approx. 123 mN mm 2), assessed in vitro, implies preserved intrinsic contractile function in all muscles of the oldest-old and were well correlated (r = 0.81). Conclusion: These findings suggest that in the oldest-old, neither advanced ageing nor disuse, per se, impacts intrinsic skeletal muscle function, as assessed in vitro. However, in vivo, muscle function is attenuated by age and exacerbated by disuse, implicating factors other than skeletal muscle, such as neuromuscular control, in this diminution of function. Keywords in vitro, in vivo, oldest-old, sarcopeni

ChantSong pour Mont Ségur

Traduzione poetica dall’italiano in inglese di tre poems del poeta italiano Daniel Maria Mancini: “ChantSong Pour Mont Ségur” sez. I, II e IV”, per un volume antologico che raccoglie l’omaggio poetico dedicato al poeta americano Ezra Pound (Sala Capizucchi, Roma) in occasione della 23^ Ezra Pound International Conference “Roma Amor: Pound, Love and Rome” (Roma: 30 giugno-4 luglio 2009)Poetic translation from Italian into English of three poems of the Italian poet Daniel Maria Mancini: “ChantSong Pour Mont Ségur” parts I, II e IV, for a volume anthology collecting poetic homages to Ezra Pound read in a special poetry reading (Sala Capizucchi, Rome) during the 23rd Ezra Pound International Conference “Roma Amor: Pound, Love and Rome” (Rome: 30 June- 4 July 2009

Allosteric modulation of zinc speciation by fatty acids

Background: Serum albumin is the major protein component of blood plasma and is responsible for the circulatory transport of a range of small molecules that include fatty acids, hormones, metal ions and drugs. Studies examining the ligand-binding properties of albumin make up a large proportion of the literature. However, many of these studies do not address the fact that albumin carries multiple ligands (including metal ions) simultaneously in vivo. Thus the binding of a particular ligand may influence both the affinity and dynamics of albumin interactions with another. Scope of review: Here we review the Zn2 + and fatty acid transport properties of albumin and highlight an important interplay that exists between them. Also the impact of this dynamic interaction upon the distribution of plasma Zn2 +, its effect upon cellular Zn2 + uptake and its importance in the diagnosis of myocardial ischemia are considered. Major conclusions: We previously identified the major binding site for Zn2 + on albumin. Furthermore, we revealed that Zn2 +-binding at this site and fatty acid-binding at the FA2 site are interdependent. This suggests that the binding of fatty acids to albumin may serve as an allosteric switch to modulate Zn2 +-binding to albumin in blood plasma. General significance: Fatty acid levels in the blood are dynamic and chronic elevation of plasma fatty acid levels is associated with some metabolic disorders such as cardiovascular disease and diabetes. Since the binding of Zn2 + to albumin is important for the control of circulatory/cellular Zn2 + dynamics, this relationship is likely to have important physiological and pathological implications. This article is part of a Special Issue entitled Serum Albumin

Restos humanos do povoado pré-histórico de Leceia : estudos da antropologia física

Fez-se o estudo de material osteológico e dentário, com a sua inventariação, observação osteométrica e exames radiológicos, à lupa binocular e ao microscópio electrónico de reflexão, nas alterações que se revelaram patológicas.info:eu-repo/semantics/publishedVersio

The Religion of Beauty and the Veil of the Graces

Le Grazie, carme materialmente incompiuto, viene qui inteso come un testo organico e compiuto da una prospettiva mitico-simbolica. Si sottolinea come Foscolo intenda il testo poetico come luogo d’origine del bello sensibile. Assolto il testo delle Grazie da ogni forma di decorativismo, l’autore interpreta il carme come fonte di una religione poetica tesa alla rinascita spirituale, culturale e politica dell’Italia. Se nei Sepolcri si celebra il passaggio dalla barbarie alla civiltà, nelle Grazie il mito dell’eros sublimato si manifesta come moderna configurazione della poesia elevata, custode di quella antica