4,322 research outputs found
The determination and evaluation of Nitinol constitutive models for finite element analysis
Superelastic Ni-Ti (Nitinol) is a member of the shape memory alloy (SMA) family of metals. The physical properties of Nitinol are highly dependant on a number of factors, including manufacturing method, subsequent processing, operating temperature, and strain rate. These factors complicate the prescription of material constitutive models, leading to complexities in the computational analysis of Nitinol components. The current work explores the limitations in the Nitinol material model available in existing commercial finite element (FE) software using a series of specially design experimental tests and representative FE models
SACOC: A spectral-based ACO clustering algorithm
The application of ACO-based algorithms in data mining is growing over the last few years and several supervised and unsupervised learning algorithms have been developed using this bio-inspired approach. Most recent works concerning unsupervised learning have been focused on clustering, where ACO-based techniques have showed a great potential. At the same time, new clustering techniques that seek the continuity of data, specially focused on spectral-based approaches in opposition to classical centroid-based approaches, have attracted an increasing research interest–an area still under study by ACO clustering techniques. This work presents a hybrid spectral-based ACO clustering algorithm inspired by the ACO Clustering (ACOC) algorithm. The proposed approach combines ACOC with the spectral Laplacian to generate a new search space for the algorithm in order to obtain more promising solutions. The new algorithm, called SACOC, has been compared against well-known algorithms (K-means and Spectral Clustering) and with ACOC. The experiments measure the accuracy of the algorithm for both synthetic datasets and real-world datasets extracted from the UCI Machine Learning Repository
Appearance-based localization for mobile robots using digital zoom and visual compass
This paper describes a localization system for mobile robots moving in dynamic indoor environments, which uses probabilistic integration of visual appearance and odometry information. The approach is based on a novel image matching algorithm for appearance-based place recognition that integrates digital zooming, to extend the area of application, and a visual compass. Ambiguous information used for recognizing places is resolved with multiple hypothesis tracking and a selection procedure inspired by Markov localization. This enables the system to deal with perceptual aliasing or absence of reliable sensor data. It has been implemented on a robot operating in an office scenario and the robustness of the approach demonstrated experimentally
The transition of smooth muscle cells from a contractile to a migratory, phagocytic phenotype : direct demonstration of phenotypic modulation
Atherosclerotic plaques are populated with smooth muscle cells (SMCs) and macrophages. SMCs are thought to accumulate in plaques because fully-differentiated, contractile SMCs reprogram into a ‘synthetic’ migratory phenotype, so-called phenotypic modulation, whilst plaque macrophages are thought to derive from blood-borne myeloid cells. Recently, these views have been challenged, with reports that SMC phenotypic modulation may not occur during vascular remodelling and that plaque macrophages may not be of haematopoietic origin. Following the fate of SMCs is complicated by the lack of specific markers for the migratory phenotype and direct demonstrations of phenotypic modulation are lacking. Therefore, we employed long-term, high-resolution, time-lapse microscopy to track the fate of unambiguously identified, fully-differentiated, contractile SMCs in response to the growth factors present in serum. Phenotypic modulation was clearly observed. The highly-elongated, contractile SMCs initially rounded up, for 1-3 days, before spreading outwards. Once spread, the SMCs became motile and displayed dynamic cell-cell communication behaviours. Significantly, they also displayed clear evidence of phagocytic activity. This macrophage-like behaviour was confirmed by their internalisation of 1µm fluorescent latex beads. However, migratory SMCs did not uptake acetylated low-density lipoprotein or express the classic macrophage marker CD68. These results directly demonstrate that SMCs may rapidly undergo phenotypic modulation and develop phagocytic capabilities. Resident SMCs may provide a potential source of macrophages in vascular remodelling
Replicators in Fine-grained Environment: Adaptation and Polymorphism
Selection in a time-periodic environment is modeled via the two-player
replicator dynamics. For sufficiently fast environmental changes, this is
reduced to a multi-player replicator dynamics in a constant environment. The
two-player terms correspond to the time-averaged payoffs, while the three and
four-player terms arise from the adaptation of the morphs to their varying
environment. Such multi-player (adaptive) terms can induce a stable
polymorphism. The establishment of the polymorphism in partnership games
[genetic selection] is accompanied by decreasing mean fitness of the
population.Comment: 4 pages, 2 figure
Statistical significance of communities in networks
Nodes in real-world networks are usually organized in local modules. These
groups, called communities, are intuitively defined as sub-graphs with a larger
density of internal connections than of external links. In this work, we
introduce a new measure aimed at quantifying the statistical significance of
single communities. Extreme and Order Statistics are used to predict the
statistics associated with individual clusters in random graphs. These
distributions allows us to define one community significance as the probability
that a generic clustering algorithm finds such a group in a random graph. The
method is successfully applied in the case of real-world networks for the
evaluation of the significance of their communities.Comment: 9 pages, 8 figures, 2 tables. The software to calculate the C-score
can be found at http://filrad.homelinux.org/cscor
The adaptations of a quality of life questionnaire for routine use in clinical practice: the Chronic Respiratory Disease Questionnaire in Cystic Fibrosis.
A Standard Input Format for Multiperiod Stochastic Linear Programs
Data conventions for the automatic input of multiperiod stochastic linear programs are described. The input format is based on the MPSX standard and is designed to promote the efficient conversion of originally deterministic problems by introducing stochastic variants in separate files. A flexible "header" syntax generates a useful variety of stochastic dependencies. An extension using the NETGEN format is proposed for stochastic network programs
Histopathologic alterations associated with the transplanted homologous dog liver
Homotransplanted livers in dogs developed mononuclear, lymphocytic and plasmacytic infiltration and hepatic cell degeneration roughly paralleling survival time. Extensive histologic alterations of host reticuloendothelial structures occurred. Proliferation and infiltration of mononuclear cells, principally plasmacytes, were noted in lung, kidney, perirenal supportive tissue, bone marrow, and lymph nodes. Lymph nodes, in addition, were characterized by cortical and follicular depletion. These changes were considered to represent extensive host reticuloendothelial mobilization coincident to liver homotransplant rejection. The relation between these alterations and those found in other hypersensitivity states is discussed. © 1962
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