174 research outputs found
Juvenile justice through a gender variant lens : an exploratory study of the experience of providers working with gender variant youth in California juvenile justice facilities
This qualitative study aimed to explore the experience of service providers in juvenile justice facilities in the San Francisco Bay Area, specifically with regard to their work with gender variant youth. Additionally, it focused on how SB 518, the CA Juvenile Justice Safety and Protection Act, impacted service provision within the juvenile justice system. Qualitative interviews were conducted with 13 providers who were employed at the time of SB 518 passing. The findings suggest that gender variant youth are present in juvenile justice facilities and face multiple challenges while navigating the juvenile justice system. Providers interviewed did not have an awareness of the passing of SB 518, nor of ways in which it impacted service provision with the gender variant population. Providers were unaware of any existing systems, policies, or procedures in juvenile justice facilities designed to support the needs of gender variant youth. Moreover, providers interviewed for the purposes of this study held varying impressions about ways in which they provided services to gender variant youth in their care. Much of what the limited existing data on this topic conveys is similar to that of what these study findings imply
Evaluating the criteria for successful elections in post-conflict countries : a case study including Iraq, Sierra Leone, and Bosnia and Herzegovina
Indiana University-Purdue University Indianapolis (IUPUI)Previous research on post-conflict elections has found several criteria important in determining if an area is ready to hold elections and whether or not it is likely to succeed. Although rarely ranked in any determination of importance, several concepts are present in most post-conflict election research. Additionally, there is not an agreed set of standard criteria upon which success can be assumed. When researching the post-conflict election literature two questions arise: (1) is there a set of criteria established to determine if an area is ready to conduct post-conflict elections, and (2) do all criteria need to be present in order to ensure successful post-conflict elections? Most research agrees on common criteria but highlights or researches one dominant criterion, to which is then often attributed to the success of an election. This is found in Krishna Kumarâs focus on international assistance (Kumar, 1998), Staffan Lindbergâs attribution of success to repetition of the election process (Lindberg, 2006), Paul Collierâs focus on per capita income (Collier, 2009), and Marie-Soleil Frereâs research on post-conflict elections and the media (Frere, 2011). When reviewing multiple research sources, it is likely several factors at various times and in various elections will be credited with being the single source criterion for success. This kind of past research is well supported and conclusively argued, but still fails to provide a scope of understanding outside of a single event. In other words, it is case specific and not comparatively applicable across cases. Although this thesis does not intend to âMcDonaldizeâ (Ritzer, 2009) the process of democratization, it does propose to define a common set of criteria necessary, even if in varying degrees, to conduct successful elections in post-conflict environments
Treating to target in psoriatic arthritis: assessing real-world outcomes and optimising therapeutic strategy for adults with psoriatic arthritis-study protocol for the MONITOR-PsA study, a trials within cohorts study design.
BACKGROUND: The Tight Control of psoriatic arthritis (TICOPA) trial confirmed improved clinical outcomes with a treat to target (T2T) strategy in psoriatic arthritis (PsA). This consisted of 4-weekly review and escalation of 'step up' therapy (single disease modifying therapy (DMARD), combination DMARDs and then biologics) based on remission criteria. Based on this, a T2T approach is supported by European PsA treatment recommendations. However, it is not commonly implemented in routine care primarily due to feasibility and cost concerns. In the TICOPA trial, the same treatment regime was used for all participants regardless of their disease profile. Despite the recognition of PsA as a highly heterogeneous condition, no studies have tailored which drugs are used depending on disease severity. The cohort will establish real world outcomes for the T2T approach in PsA and also form the basis of a trials within cohorts (TWiCs) design to test alternative therapeutic approaches within embedded clinical trials providing an evidence base for treatment strategy in PsA. METHODS: The Multicentre Observational Initiative in Treat to target Outcomes in Psoriatic Arthritis (MONITOR-PsA) cohort will apply a T2T approach within routine care. It will recruit newly diagnosed adult patients with PsA starting systemic therapies. The cohort is observational allowing routine therapeutic care within NHS clinics but a T2T approach will be supported when monitoring treatment within the cohort. Eligible participants will be adults (â„18âyears) with active PsA with â„ 1 tender or swollen joints or enthesis who have not previously had treatment with DMARDs for articular disease. DISCUSSION: This study is the first TWiC designed to support a fully powered randomised drug trial. The results from the observational cohort will be compared with those observed in the TICOPA trial investigating the clinical effectiveness and health care costs of the pragmatic T2T approach. Nested trials will provide definitive RCT evidence establishing the optimal management of PsA within the T2T approach. The TWiCs design allows robust generalizability to routine healthcare, avoids disappointment bias, aids recruitment and in future will allow assessment of longer-term outcomes. TRIAL REGISTRATION: ClinicalTrials.gov NCT03531073 . Retrospectively registered on 21 May 2018
Angular Momentum Evolution in Dark Matter Halos
We have analyzed high resolution N-body simulations of dark matter halos,
focusing specifically on the evolution of angular momentum. We find that not
only is individual particle angular momentum not conserved, but the angular
momentum of radial shells also varies over the age of the Universe by up to
factors of a few. We find that torques from external structure are the most
likely cause for this distribution shift. Since the model of adiabatic
contraction that is often applied to model the effects of galaxy evolution on
the dark-matter density profile in a halo assumes angular momentum
conservation, this variation implies that there is a fundamental limit on the
possible accuracy of the adiabatic contraction model in modeling the response
of DM halos to the growth of galaxies.Comment: 16 pages, 9 figures, accepted for publication in MNRA
East Bay Coalition for the Homeless: Branding Study and Marketing Strategy
There are a number of potential positioning strategies. The two which make the most sense for the EBCH are to âposition the EBCH away from others in the categoryâ and to âposition the EBCH as unique.â These strategies have the advantage of setting the EBCH apart from the other organizations that address homelessness. Occupying its own âpositionâ in the minds of potential and current donors is not only an effective communications/marketing strategy but also a less costly one because it avoids head-to-head competition and comparisons
Case-finding and genetic testing for familial hypercholesterolaemia in primary care
Objective: Familial Hypercholesterolaemia (FH) is a common inherited disorder causing premature heart disease and death. We have developed novel case-finding algorithms (FAMCAT version 1 & 2) for application in primary care, to improve detection of FH and have evaluated their performance, at 95% specificity, to detect genetically-confirmed FH in the general population. We also compared these algorithms to established clinical case-finding criteria. Methods: Prospective validation study, in 14 general practices, recruiting participants from the general adult population with cholesterol documented. For 260 participants with available health records, we determined possible FH cases based on FAMCAT thresholds, Dutch Lipid Clinic Network (DLCN) score, Simon-Broome criteria and national recommended cholesterol thresholds (total cholesterol > 9.0 mmol/L if â„30 years or > 7.5 mmol/L i
The Origin of Extended Disk Galaxies at z=2
Galaxy formation models typically assume that the size and rotation speed of
galaxy disks are largely dictated by the mass, concentration, and spin of their
surrounding dark matter haloes. Equally important, however, are the fraction of
baryons in the halo that collect into the central galaxy, as well as the net
angular momentum that they are able to retain during its assembly process. We
explore the latter using a set of four large cosmological N-body/gasdynamical
simulations drawn from the OWLS (OverWhelmingly Large Simulations) project.
These runs differ only in their implementation of feedback from supernovae. We
find that, when expressed as fractions of their virial values, galaxy mass and
net angular momentum are tightly correlated. Galaxy mass fractions,
m_d=M_gal/M_vir, depend strongly on feedback, but only weakly on halo mass or
spin over the halo mass range explored here (M_vir>1e11 h^{-1}M_sun). The
angular momentum of a galaxy, j_d=J_gal/J_vir, correlates with m_d in a manner
that is insensitive to feedback and that deviates strongly from the simple j_d
= m_d assumption often adopted in semi-analytic models of galaxy formation. The
m_d-j_d correlation implies that, in a given halo, galaxy disk size is maximal
when the central galaxy makes up a substantial fraction (~20%-30%) of all
baryons within the virial radius. At z=2, such systems may host gaseous disks
with radial scale lengths as large as those reported for star-forming disks by
the SINS survey, even in moderately massive haloes of average spin. Extended
disks at z=2 may thus signal the presence of systems where galaxy formation has
been particularly efficient, rather than the existence of haloes with unusually
high spin parameter.Comment: 5 pages, 4 figures. Accepted for publication in MNRAS Letters. Minor
changes to match published versio
Factors influencing routine cognitive impairment screening in older atârisk drinkers: Findings from a qualitative study in the United Kingdom
Cognitive Impairment (CI) screening is recommended for those engaged in harmful levels of alcohol use. However, there is a lack of evidence on implementation. This paper explores the barriers and facilitators to CI screening experienced across a service specifically for older drinkers. The findings draw on data gathered as part of an evaluation of a multilevel programme to reduce alcoholârelated harm in adults aged 50 and over in five demonstration areas across the United Kingdom. It is based on qualitative interviews and focus groups with 14 service providers and 22 service users. Findings are presented thematically under the section headings: acceptability of screening, interpretation and making sense of screening and treatment options. It is suggested that engagement with CI screening is most likely when its fit with agency culture and its purpose is clear; where service providers have the technical skills to administer and discuss the results of screening with service users; and where those undertaking screening have had the opportunity to reflect on their own experience of being screened. Engagement with CI screening is also most likely where specific intervention pathways and engagement practices can be accessed to respond to assessed need
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