519 research outputs found
Scaling Laws for Advection Dominated Flows: Applications to Low Luminosity Galactic Nuclei
We present analytical scaling laws for self-similar advection dominated
flows. The spectra from these systems range from 10 - 10 Hz, and
are determined by considering cooling of electrons through synchrotron,
bremsstrahlung, and Compton processes. We show that the spectra can be quite
accurately reproduced without detailed numerical calculations, and that there
is a strong testable correlation between the radio and X-ray fluxes from these
systems. We describe how different regions of the spectrum scale with the mass
of the accreting black hole, , the accretion rate of the gas, , and
the equilibrium temperature of the electrons, . We show that the universal
radio spectral index of 1/3 observed in most elliptical galaxies (Slee et al.
1994) is a natural consequence of self-absorbed synchrotron radiation from
these flows. We also give expressions for the total luminosity of these flows,
and the critical accretion rate, , above which the advection
solutions cease to exist. We find that for most cases of interest the
equilibrium electron temperature is fairly insensitive to , , and
parameters in the model. We apply these results to low luminosity black holes
in galactic nuclei. We show that the problem posed by Fabian & Canizares (1988)
of whether bright elliptical galaxies host dead quasars is resolved, as pointed
out recently by Fabian & Rees (1995), by considering advection-dominated flows.Comment: 30 pages, 5 postscript files. Accepted to ApJ. Also available
http://cfa-www.harvard.edu/~rohan/publications.htm
The Spectrum and Variability of Circular Polarization in Sagittarius A* from 1.4 to 15 GHz
We report here multi-epoch, multi-frequency observations of the circular
polarization in Sagittarius A*, the compact radio source in the Galactic
Center. Data taken from the VLA archive indicate that the fractional circular
polarization at 4.8 GHz was -0.31% with an rms scatter of 0.13% from 1981 to
1998, in spite of a factor of 2 change in the total intensity. The sign
remained negative over the entire time range, indicating a stable magnetic
field polarity. In the Summer of 1999 we obtained 13 epochs of VLA A-array
observations at 1.4, 4.8, 8.4 and 15 GHz. In May, September and October of 1999
we obtained 11 epochs of Australia Telescope Compact Array observations at 4.8
and 8.5 GHz. In all three of the data sets, we find no evidence for linear
polarization greater than 0.1% in spite of strong circular polarization
detections. Both VLA and ATCA data sets support three conclusions regarding the
fractional circular polarization: the average spectrum is inverted with a
spectral index ~0.5 +/- 0.2; the degree of variability is roughly constant on
timescales of days to years; and, the degree of variability increases with
frequency. We also observed that the largest increase in fractional circular
polarization was coincident with the brightest flare in total intensity.
Significant variability in the total intensity and fractional circular
polarization on a timescale of 1 hour was observed during this flare,
indicating an upper limit to the size of 70 AU at 15 GHz. The fractional
circular polarization at 15 GHz reached -1.1% and the spectral index is
strongly inverted during this flare. We conclude that the spectrum has two
components that match the high and low frequency total intensity components.
(abridged)Comment: Accepted for publication in ApJ, 40 pages, 18 figure
Ram pressure stripping and galaxy orbits: The case of the Virgo cluster
We investigate the role of ram pressure stripping in the Virgo cluster using
N-body simulations. Radial orbits within the Virgo cluster's gravitational
potential are modeled and analyzed with respect to ram pressure stripping. The
N-body model consists of 10000 gas cloud complexes which can have inelastic
collisions. Ram pressure is modeled as an additional acceleration on the clouds
located at the surface of the gas distribution in the direction of the galaxy's
motion within the cluster. We made several simulations changing the orbital
parameters in order to recover different stripping scenarios using realistic
temporal ram pressure profiles. We investigate systematically the influence of
the inclination angle between the disk and the orbital plane of the galaxy on
the gas dynamics. We show that ram pressure can lead to a temporary increase of
the central gas surface density. In some cases a considerable part of the total
atomic gas mass (several 10^8 M_solar) can fall back onto the galactic disk
after the stripping event. A quantitative relation between the orbit parameters
and the resulting HI deficiency is derived containing explicitly the
inclination angle between the disk and the orbital plane. The comparison
between existing HI observations and the results of our simulations shows that
the HI deficiency depends strongly on galaxy orbits. It is concluded that the
scenario where ram pressure stripping is responsible for the observed HI
deficiency is consistent with all HI 21cm observations in the Virgo cluster.Comment: 29 pages with 21 figures. Accepted for publication in Ap
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PNIPAM coated biopolymer multilayers for temperature-mediated drug release
Shape matters: effects of silver nanospheres and wires on human alveolar epithelial cells
<p>Abstract</p> <p>Background</p> <p>In nanotoxicology, the exact role of particle shape, in relation to the composition, on the capacity to induce toxicity is largely unknown. We investigated the toxic and immunotoxic effects of silver wires (length: 1.5 - 25 ÎŒm; diameter 100 - 160 nm), spherical silver nanoparticles (30 nm) and silver microparticles (<45 ÎŒm) on alveolar epithelial cells (A549).</p> <p>Methods</p> <p>Wires and nanoparticles were synthesized by wet-chemistry methods and extensively characterized. Cell viability and cytotoxicity were assessed and potential immunotoxic effects were investigated. To compare the effects on an activated and a resting immune system, cells were stimulated with rhTNF-α or left untreated. Changes in intracellular free calcium levels were determined using calcium imaging. Finally, ion release from the particles was assessed by ICP-MS and the effects of released ions on cell viability and cytotoxicity were tested.</p> <p>Results</p> <p>No effects were observed for the spherical particles, whereas the silver wires significantly reduced cell viability and increased LDH release from A549 cells. Cytokine promoter induction and NF-ÎșB activation decreased in a concentration dependent manner similar to the decrease seen in cell viability. In addition, a strong increase of intracellular calcium levels within minutes after addition of wires was observed. This toxicity was not due to free silver ions, since the samples with the highest ion release did not induce toxicity and ion release control experiments with cells treated with pre-incubated medium did not show any effects either.</p> <p>Conclusions</p> <p>These data showed that silver wires strongly affect the alveolar epithelial cells, whereas spherical silver particles had no effect. This supports the hypothesis that shape is one of the important factors that determine particle toxicity.</p
Multi-fractional analysis of molecular diffusion in polymer multilayers by FRAP: a new simulation-based approach
Comprehensive analysis of the multifractional molecular diffusion provides a deeper understanding of the diffusion phenomenon in the fields of material science, molecular and cell biology, advanced biomaterials, etc. Fluorescence recovery after photobleaching (FRAP) is commonly employed to probe the molecular diffusion. Despite FRAP being a very popular method, it is not easy to assess multifractional molecular diffusion due to limited possibilities of approaches for analysis. Here we present a novel simulation-optimization-based approach (S-approach) that significantly broadens possibilities of the analysis. In the S-approach, possible fluorescence recovery scenarios are primarily simulated and afterward compared with a real measurement while optimizing parameters of a model until a sufficient match is achieved. This makes it possible to reveal multifractional molecular diffusion. Fluorescent latex particles of different size and fluorescein isothiocyanate in an aqueous medium were utilized as test systems. Finally, the S-approach has been used to evaluate diffusion of cytochrome c loaded into multilayers made of hyaluronan and polylysine. Software for evaluation of multifractional molecular diffusion by S-approach has been developed aiming to offer maximal versatility and user-friendly way for analysis
HI deficiency in the galaxy cluster ACO 3627. ATCA observations in the Great Attractor region
ATCA 21 cm HI observations of the rich galaxy cluster ACO 3627 in the Great
Attractor region are presented. Three fields of 30' diameter located within one
Abell radius of ACO 3627 were observed with a resolution of 15'' and an rms
noise of \sim 1 mJy/beam. Only two galaxies were detected in these fields. We
compare their HI distribution to new optical R-band images and discuss their
velocity fields. The first galaxy is a gas-rich unperturbed spiral whereas the
second shows a peculiar HI distribution. The estimated 3-sigma HI mass limit of
our observations is \sim 7 x 10^8 M_{\odot} for a line width of 150 km s^{-1}.
The non-detection of a considerable number of luminous spiral galaxies
indicates that the spiral galaxies are HI deficient. The low detection rate is
comparable to the HI deficient Coma cluster (Bravo-Alfaro et al. 2000). ACO
3627 is a bright X-ray cluster. We therefore suspect that ram pressure
stripping is responsible for the HI deficiency of the bright cluster spirals.Comment: 9 pages with 7 figures; A&A, in pres
Temperature effect on the build-up of exponentially growing polyelectrolyte multilayers. An exponential-to-linear transition point
In this study, the effect of temperature on the build-up of exponentially growing polyelectrolyte multilayer films was investigated. It aims at understanding the multilayer growth mechanism as crucially important for the fabrication of tailor-made multilayer films. Model poly(L-lysine)/hyaluronic acid (PLL/HA) multilayers were assembled in the temperature range of 25â85 1C by layer-by-layer deposition using a dipping method. The film growth switches from the exponential to the linear regime at the transition point as a result of limited polymer diffusion into the film. With the increase of the build-up temperature the film growth rate is enhanced in both regimes; the position of the transition point shifts to a higher number of deposition steps confirming the diffusion-mediated growth mechanism. Not only the faster polymer diffusion into the film but also more porous/permeable film structure are responsible for faster film growth at higher preparation temperature. The latter mechanism is assumed from analysis of the film growth rate upon switching of the preparation temperature during the film growth. Interestingly, the as-prepared films are equilibrated and remain intact (no swelling or shrinking) during temperature variation in the range of 25â45 1C. The average activation energy for complexation between PLL and HA in the multilayers calculated from the Arrhenius plot has been found to be about 0.3 kJ mol 1 for monomers of PLL. Finally, the following processes known to be dependent on temperature are discussed with respect to the multilayer growth: (i) polymer diffusion, (ii) polymer conformational changes, and (iii) inter-polymer interactions
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