Understanding jumping to conclusions in patients with persecutory delusions: working memory and intolerance of uncertainty

Background. Persecutory delusions are a key psychotic experience. A reasoning style known as ‘jumping to conclusions’ (JTC) – limited information gathering before reaching certainty in decision making – has been identified as a contributory factor in the occurrence of delusions. The cognitive processes that underpin JTC need to be determined in order to develop effective interventions for delusions. In the current study two alternative perspectives were tested: that JTC partially results from impairment in information-processing capabilities and that JTC is a motivated strategy to avoid uncertainty.Method. A group of 123 patients with persistent persecutory delusions completed assessments of JTC (the 60:40 beads task), IQ, working memory, intolerance of uncertainty, and psychiatric symptoms. Patients showing JTC were compared with patients not showing JTC.Results. A total of 30 (24%) patients with delusions showed JTC. There were no differences between patients who did and did not jump to conclusions in overall psychopathology. Patients who jumped to conclusions had poorer working memory performance, lower IQ, lower intolerance of uncertainty and lower levels of worry.Working memory and worry independently predicted the presence of JTC.Conclusions. Hasty decision making in patients with delusions may partly arise from difficulties in keeping information in mind. Interventions for JTC are likely to benefit from addressing working memory performance, while in vivo techniques for patients with delusions will benefit from limiting the demands on working memory. The study provides little evidence for a contribution to JTC from top down motivational beliefs about uncertainty

Investigating Heating and Cooling in the BCS & B55 Cluster Samples

We study clusters in the BCS cluster sample which are observed by Chandra and are more distant than redshift, z>0.1. We select from this subsample the clusters which have both a short central cooling time and a central temperature drop, and also those with a central radio source. Six of the clusters have clear bubbles near the centre. We calculate the heating by these bubbles and express it as the ratio r_heat/r_cool=1.34+/-0.20. This result is used to calculate the average size of bubbles expected in all clusters with central radio sources. In three cases the predicted bubble sizes approximately match the observed radio lobe dimensions. We combine this cluster sample with the B55 sample studied in earlier work to increase the total sample size and redshift range. This extended sample contains 71 clusters in the redshift range 0<z<0.4. The average distance out to which the bubbles offset the X-ray cooling in the combined sample is at least r_heat/r_cool=0.92+/-0.11. The distribution of central cooling times for the combined sample shows no clusters with clear bubbles and t_cool>1.2Gyr. An investigation of the evolution of cluster parameters within the redshift range of the combined samples does not show any clear variation with redshift.Comment: 12 pages, 9 figures, accepted for publication in MNRA

Rasch analysis of the 23-item version of the Roland Morris Disability Questionnaire

Objective: To determine the psychometric properties of the 23-item version of the Roland Morris Disability Questionnaire (RMDQ-23) and to quantify their stability across 2 cultures/languages and 2 types of care-settings. Methods: Rasch analysis of data from 1,000 patients with low back pain from primary care (UK and Denmark) and secondary care (Denmark). Results: The RMDQ-23 is unidimensional if local item dependency issues are accommodated, but contains several misfitting or overdiscriminating items, some poor targeting of items, and the scoring of 4-5 items is differentially affected by common clinical characteristics (such as age, gender, pain intensity, pain duration and care setting), depending on the country. Conclusion: As similar results have been found for the RMDQ-24, we believe it is timely to reconsider whether: (i) the RMDQ should be reconstructed using an item-response theory-based approach that includes consideration of new items and response options; or (ii) the use of alternative questionnaires should be recommended, such as the Oswestry Disability Index, that have shown evidence of fitting the Rasch model; or (iii) a completely new condition-specific questionnaire should be developed, perhaps utilizing a computerized adaptive testing platform

Development of Red Clover with High Levels of Resistance to Root-Knot Nematodes

Red clover (Trifolium pratense L.), is grown in many areas of the world, but production in subtropical regions may be limited by susceptibility to root-knot nematodes (Meloidogyne spp.) (RKN). Selection for early vigor in RKN infested soils resulted in moderate RKN tolerance in ‘Cherokee’. However, improved RKN resistance in red clover was needed. Seven additional cycles of greenhouse selection using Cherokee as a base population developed a population (FLMR7) with high RKN resistance. When FLMR7 was infested with M. arenaria, M. hapla, M. incognita, or M. javanica, numbers of galls and egg masses were lower than on Cherokee or an earlier cycle of selection (FLMR6). The resistance mechanisms appeared to delay and reduce RKN maturation at all life stages, including reduction in number of egg masses per plant. Preliminary evidence suggests that resistance may interact with higher soil temperatures

AGN-Induced Cavities in NGC 1399 and NGC 4649

We present an analysis of archival Chandra and VLA observations of the E0 galaxy NGC 1399 and the E2 galaxy NGC 4649 in which we investigate cavities in the surrounding X-ray emitting medium caused by the central AGN. We calculate the jet power required for the AGN to evacuate these cavities and find values of ~8x10^{41} erg/s and ~14x10^{41} erg/s for the lobes of NGC 1399 and ~7x10^{41} erg/s and ~6x10^{41} erg/s for those of NGC 4649. We also calculate the k/f values for each cavity, where k is the ratio of the total particle energy to that of electrons radiating in the range of 10 MHz to 10 GHz, and f is the volume filling factor of the plasma in the cavity. We find that the values of k/f for the lobes of NGC 1399 are ~93 and ~190, and those of the lobes of NGC 4649 are ~15000 and ~12000. We conclude that the assumed spectrum describes the electron distribution in the lobes of NGC 1399 reasonably well, and that there are few entrained particles. For NGC 4649, either there are many entrained particles or the model spectrum does not accurately describe the population of electrons.Comment: 8 pages, 2 figures, accepted for publication in MNRA

Ethnic discrimination in private rental housing markets in Australia

Over the last two decades new and significant demographic, economic, social and environmental changes and challenges have shaped the production and consumption of housing in Australia and the policy settings that attempt to guide these processes. These changes and challenges, as outlined in this book, are many and varied. While these issues are new they raise timeless questions around affordability, access, density, quantity, type and location of housing needed in Australian towns and cities. The studies presented in this text also provide a unique insight into a range of housing production, consumption and policy issues that, while based in Australia, have implications that go beyond this national context. For instance how do suburban-based societies adjust to the realities of aging populations, anthropogenic climate change and the significant implications such change has for housing? How has policy been translated and assembled in specific national contexts? Similarly, what are the significantly different policy settings the production and consumption of housing in a post-Global Financial Crisis period require? Framed in this way this book accounts for and responds to some of the key housing issues of the 21st century

Multilingual assessment of early child development: Analyses from repeated observations of children in Kenya.

In many low- and middle-income countries, young children learn a mother tongue or indigenous language at home before entering the formal education system where they will need to understand and speak a countrys official language(s). Thus, assessments of children before school age, conducted in a nations official language, may not fully reflect a childs development, underscoring the importance of test translation and adaptation. To examine differences in vocabulary development by language of assessment, we adapted and validated instruments to measure developmental outcomes, including expressive and receptive vocabulary. We assessed 505 2-to-6-year-old children in rural communities in Western Kenya with comparable vocabulary tests in three languages: Luo (the local language or mother tongue), Swahili, and English (official languages) at two time points, 5-6&nbsp;weeks apart, between September 2015 and October 2016. Younger children responded to the expressive vocabulary measure exclusively in Luo (44%-59% of 2-to-4-year-olds) much more frequently than did older children (20%-21% of 5-to-6-year-olds). Baseline receptive vocabulary scores in Luo (β&nbsp;=&nbsp;0.26, SE&nbsp;=&nbsp;0.05, p&nbsp;&lt;&nbsp;0.001) and Swahili (β&nbsp;=&nbsp;0.10, SE&nbsp;=&nbsp;0.05, p&nbsp;=&nbsp;0.032) were strongly associated with receptive vocabulary in English at follow-up, even after controlling for English vocabulary at baseline. Parental Luo literacy at baseline (β&nbsp;=&nbsp;0.11, SE&nbsp;=&nbsp;0.05, p&nbsp;=&nbsp;0.045) was associated with child English vocabulary at follow-up, while parental English literacy at baseline was not. Our findings suggest that multilingual testing is essential to understanding the developmental environment and cognitive growth of multilingual children