15,085 research outputs found
Water vapor in the lower stratosphere measured from aircraft flight
Water vapor in the lower stratosphere was measured in situ by two aluminum oxide hygrometers mounted on the nose of an RB57 aircraft. Data were taken nearly continuously from January to May 1974 from an altitude of approximately 11 km to 19 km as the aircraft flew between 70 deg N and 50 deg S over the land areas in the Western Hemisphere. Pseudomeridional cross sections of water vapor and temperature are derived from the flight data and show mixing ratios predominantly between 2 and 4 micron gm/gm with an extreme range of 1 to 8 micron gm/gm. Measurement precision is estimated by comparing the simultaneously measured values from the two flight hygrometer systems. Accuracy is estimated to be about + or - 40 percent at 19 km. A height-averaged latitudinal cross section of water vapor shows symmetry of wet and dry zones
Long-duration exercise at moderate work loads
Metabolic effects of long duration exercise at moderate work loads including tables of heart rate, rectal temperature, minute volume, water balance, and respiratory quotien
On the Use of Group Theoretical and Graphical Techniques toward the Solution of the General N-body Problem
Group theoretic and graphical techniques are used to derive the N-body wave
function for a system of identical bosons with general interactions through
first-order in a perturbation approach. This method is based on the maximal
symmetry present at lowest order in a perturbation series in inverse spatial
dimensions. The symmetric structure at lowest order has a point group
isomorphic with the S_N group, the symmetric group of N particles, and the
resulting perturbation expansion of the Hamiltonian is order-by-order invariant
under the permutations of the S_N group. This invariance under S_N imposes
severe symmetry requirements on the tensor blocks needed at each order in the
perturbation series. We show here that these blocks can be decomposed into a
basis of binary tensors invariant under S_N. This basis is small (25 terms at
first order in the wave function), independent of N, and is derived using
graphical techniques. This checks the N^6 scaling of these terms at first order
by effectively separating the N scaling problem away from the rest of the
physics. The transformation of each binary tensor to the final normal
coordinate basis requires the derivation of Clebsch-Gordon coefficients of S_N
for arbitrary N. This has been accomplished using the group theory of the
symmetric group. This achievement results in an analytic solution for the wave
function, exact through first order, that scales as N^0, effectively
circumventing intensive numerical work. This solution can be systematically
improved with further analytic work by going to yet higher orders in the
perturbation series.Comment: This paper was submitted to the Journal of Mathematical physics, and
is under revie
Feshbach Resonance Cooling of Trapped Atom Pairs
Spectroscopic studies of few-body systems at ultracold temperatures provide
valuable information that often cannot be extracted in a hot environment.
Considering a pair of atoms, we propose a cooling mechanism that makes use of a
scattering Feshbach resonance. Application of a series of time-dependent
magnetic field ramps results in the situation in which either zero, one, or two
atoms remain trapped. If two atoms remain in the trap after the field ramps are
completed, then they have been cooled. Application of the proposed cooling
mechanism to optical traps or lattices is considered.Comment: 5 pages, 3 figures; v.2: major conceptual change
Analytic, Group-Theoretic Density Profiles for Confined, Correlated N-Body Systems
Confined quantum systems involving identical interacting particles are to
be found in many areas of physics, including condensed matter, atomic and
chemical physics. A beyond-mean-field perturbation method that is applicable,
in principle, to weakly, intermediate, and strongly-interacting systems has
been set forth by the authors in a previous series of papers. Dimensional
perturbation theory was used, and in conjunction with group theory, an analytic
beyond-mean-field correlated wave function at lowest order for a system under
spherical confinement with a general two-body interaction was derived. In the
present paper, we use this analytic wave function to derive the corresponding
lowest-order, analytic density profile and apply it to the example of a
Bose-Einstein condensate.Comment: 15 pages, 2 figures, accepted by Physics Review A. This document was
submitted after responding to a reviewer's comment
Disorder-induced microscopic magnetic memory
Using coherent x-ray speckle metrology, we have measured the influence of
disorder on major loop return point memory (RPM) and complementary point memory
(CPM) for a series of perpendicular anisotropy Co/Pt multilayer films. In the
low disorder limit, the domain structures show no memory with field cycling--no
RPM and no CPM. With increasing disorder, we observe the onset and the
saturation of both the RPM and the CPM. These results provide the first direct
ensemble-sensitive experimental study of the effects of varying disorder on
microscopic magnetic memory and are compared against the predictions of
existing theories.Comment: 4 pages, 4 figures. Accepted for publication in Physical Review
Letters in Nov. 200
Noise in laser speckle correlation and imaging techniques
We study the noise of the intensity variance and of the intensity correlation
and structure functions measured in light scattering from a random medium in
the case when these quantities are obtained by averaging over a finite number N
of pixels of a digital camera. We show that the noise scales as 1/N in all
cases and that it is sensitive to correlations of signals corresponding to
adjacent pixels as well as to the effective time averaging (due to the finite
sampling time) and spatial averaging (due to the finite pixel size). Our
results provide a guide to estimation of noise level in such applications as
the multi-speckle dynamic light scattering, time-resolved correlation
spectroscopy, speckle visibility spectroscopy, laser speckle imaging etc.Comment: submitted 14 May 201
Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors
PURPOSE: Subsets of pituitary tumors exhibit an aggressive clinical courses and recur despite surgery, radiation, and chemotherapy. Because modulation of the immune response through inhibition of T-cell checkpoints has led to durable clinical responses in multiple malignancies, we explored whether pituitary adenomas express immune-related biomarkers that could suggest suitability for immunotherapy. Specifically, programmed death ligand 1 (PD-L1) has emerged as a potential biomarker whose expression may portend more favorable responses to immune checkpoint blockade therapies. We thus investigated the expression of PD-L1 in pituitary adenomas. METHODS: PD-L1 RNA and protein expression were evaluated in 48 pituitary tumors, including functioning and non-functioning adenomas as well as atypical and recurrent tumors. Tumor infiltrating lymphocyte populations were also assessed by immunohistochemistry. RESULTS: Pituitary tumors express variable levels of PD-L1 transcript and protein. PD-L1 RNA and protein expression were significantly increased in functioning (growth hormone and prolactin-expressing) pituitary adenomas compared to non-functioning (null cell and silent gonadotroph) adenomas. Moreover, primary pituitary adenomas harbored higher levels of PD-L1 mRNA compared to recurrent tumors. Tumor infiltrating lymphocytes were observed in all pituitary tumors and were positively correlated with increased PD-L1 expression, particularly in the functional subtypes. CONCLUSIONS: Human pituitary adenomas harbor PD-L1 across subtypes, with significantly higher expression in functioning adenomas compared to non-functioning adenomas. This expression is accompanied by the presence of tumor infiltrating lymphocytes. These findings suggest the existence of an immune response to pituitary tumors and raise the possibility of considering checkpoint blockade immunotherapy in cases refractory to conventional management
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