Eastern Policy of the EU: the Visegrad Countries' Perspective. OSW Point of View, February 2003

1. After its enlargement, scheduled for 2004, the European Union will face a completely new situation at its eastern borders. This new situation calls for a new concept of the EU eastern activities, i.e. for development of the new Eastern Policy of the EU. 2. Due to a number of specific features such as geographical location, closeness of ties, direct risk factors etc., the Visegrad countries will and should be particularly interested in the process of formulating the new EU Eastern Policy. Consequently, they should be the co-makers of this policy. 3. The new EU Eastern Policy should differ fundamentally from the Union's traditional eastern relations. Firstly, its scope should not cover the entire CIS area: instead, the policy should focus on some of the European successor states of the former Soviet Union, namely Belarus, Russia and Ukraine, as well as Moldova, following the accession of Romania. It does not seem advisable to exclude the Russian Federation from this policy and to develop and implement a separate policy towards it. The new Eastern Policy should be an autonomous component and one of the most important elements in the overall foreign policy of the EU. 4. Secondly, the new Eastern Policy should be founded on the following two pillars: a region-oriented strategy, which could be called the Eastern Dimension, and reshaped strategies for individual countries. The Eastern Dimension should set up a universal framework of co-operation, defining its basic mechanisms and objectives. These should include: the adaptation assistance programme, JHA, transborder co-operation, social dialogue and transport infrastructures. The approach, however, should be kept flexible, taking into account the specific situation of each country. This purpose should be served by keeping in place the existing bilateral institutional contacts between the EU and each of its eastern neighbours, and by developing a national strategy for each neighbour

Anthropogenic factors driven phosphorus contents in Salto Grande Reservoir sediments, São Paulo State (SE Brazil)

Phosphorus is an essential element for life and, when scarce, this macronutrient is a limiting factor for primary production. Phosphorus (P) is a widely used element in the composition of fertilizers, besides being present in large quantities in domestic effluents. Its accumulation in the springs is related to the proliferation of algae and cyanobacteria. In excess, P is a pollutant that contributes greatly to the eutrophication, development of reduced conditions and deterioration of water bodies. In order to understand how the anthropogenic action affected the accumulation of P in the freshwater reservoir of Salto Grande, Americana City (São Paulo State, Brazil), the evaluation of a temporal sedimentary record was carried out. For this purpose, a sediment core collected in the reservoir of Salto Grande was studied. The sediment core recorded the reservoir history since its filling in 1950. The comparison of P concentrations along the core with the population growth curve indicates that the population growth in the surrounding region has had a direct impact on the accumulation of P in the freshwater reservoir of Salto Grande. The eutrophication history of this major continental ecosystem of São Paulo State, was reflected by this sewage-derived from loading of P

Photodynamics of Bright Subnanosecond Emission from Pure Single-Photon Sources in Hexagonal Boron Nitride

Bright and stable emitters of single indistinguishable photons are crucial for quantum technologies. The origin of the promising bright emitters recently observed in hexagonal boron nitride (hBN) still remains unclear. This study reports pure single-photon sources in multi-layered hBN at room temperature that demonstrate high emission rates. The quantum emitters are introduced with argon beam treatment and air annealing of mechanically exfoliated hBN flakes with thicknesses of 5–100 nm. Spectral and time-resolved measurements reveal the emitters have more than 1 GHz of excited-to-ground state transition rate. The observed photoswitching between dark and bright states indicates the strong sensitivity of the emitter to the electrostatic environment and the importance of the indirect excitation for the photodynamics

Quantitative Morphometric Analysis of Morphologically Similar Species of <i>Fragilaria</i> (Fragilariaceae, Bacillariophyta) Allows Detection of Non-Indigenous Taxa: A Case Study from Lake Ladoga (North of European Russia)

In Lake Ladoga (northwestern Russia), we found a diatom, putatively Fragilaria sublanceolata-baikali, an endemic species from Lake Baikal (southeastern Siberia, Russia). To determine whether this population matches a previously recognized species from Lake Baikal and assess how it differs from other similar Fragilaria taxa, we studied the valve morphology of three morphologically similar Fragilaria populations (the putative F. sublanceolata-baikali, F. pectinalis and F. perminuta) sampled in Lake Ladoga, along with a population of F. sublanceolata-baikali sampled in Lake Baikal. We used light and scanning electron microscopy with a combination of traditional and geometric morphometric methods. To analyze covariation between the valve shape and size (i.e., allometry), we examined differences in the ontogenetic–allometric trajectories at both the interspecific and intraspecific levels. In addition, the effect of size correction of the valve shape on species differentiation was tested. Traditional morphometrics revealed that F. sublanceolata-baikali is distinguished from F. pectinalis and F. perminuta by valve length, while F. pectinalis and F. perminuta are distinguished by striae density. All three species of Fragilaria showed separate and parallel allometric trajectories. In contrast, the two populations of F. sublanceolata-baikali were on a common allometric trajectory, indicating the conspecificity between these populations. Prior to allometric correction, geometric morphometrics was not able fully discriminate between the three Fragilaria species. After allometric correction, the three Fragilaria species were clearly separated in a size-corrected morphospace, whereas the two populations of F. sublanceolata-baikali formed a tightly overlapping group. Thus, we conclude that geometric morphometrics can reliably distinguish between these morphologically similar species of Fragilaria, but only after accounting for allometric shape variation. Our study confirmed morphological similarity between the two geographically distant populations of F. sublanceolata-baikali, which indicates that this taxon can be considered as invasive in Lake Ladoga

A Novel Letrozole Model Recapitulates Both the Reproductive and Metabolic Phenotypes of Polycystic Ovary Syndrome in Female Mice.

Polycystic ovary syndrome (PCOS) pathophysiology is poorly understood, due partly to lack of PCOS animal models fully recapitulating this complex disorder. Recently, a PCOS rat model using letrozole (LET), a nonsteroidal aromatase inhibitor, mimicked multiple PCOS phenotypes, including metabolic features absent in other models. Given the advantages of using genetic and transgenic mouse models, we investigated whether LET produces a similar PCOS phenotype in mice. Pubertal female C57BL/6N mice were treated for 5 wk with LET, which resulted in increased serum testosterone and normal diestrus levels of estradiol, similar to the hyperandrogenemia and follicular phase estrogen levels of PCOS women. As in PCOS, ovaries from LET mice were larger, polycystic, and lacked corpora lutea versus controls. Most LET females were acyclic, and all were infertile. LET females displayed elevated serum LH levels and higher Lhb mRNA in the pituitary. In contrast, serum FSH and Fshb were significantly reduced in LET females, demonstrating differential effects on gonadotropins, as in PCOS. Within the ovary, LET females had higher Cyp17, Cyp19, and Fsh receptor mRNA expression. In the hypothalamus, LET females had higher kisspeptin receptor mRNA expression but lower progesterone receptor mRNA levels. LET females also gained more weight than controls, had increased abdominal adiposity and adipocyte size, elevated adipose inflammatory mRNA levels, and impaired glucose tolerance, mirroring the metabolic phenotype in PCOS women. This is the first report of a LET paradigm in mice that recapitulates both reproductive and metabolic PCOS phenotypes and will be useful to genetically probe the PCOS condition

Managing the flows of gas and rules: Ukraine between the EU and Russia

The article explores the impact of the EU and Russia on domestic change in the gas sector in Ukraine. It seeks to identify the barriers to, and triggers for, Ukraine’s alignment with EU rules against the backdrop of Ukraine’s energy dependence on Russia by focusing on the institutionalization of energy relations. By studying the whole post-Soviet period, this article provides a comprehensive overview of the interplay of domestic and external factors shaping the energy sector in Ukraine and illuminates the often paradoxical effects of external influences on domestic actors’ preferences and strategies. We argue that EU influence was ineffective in overcoming domestic barriers to reforms and that it was Russia’s coercive actions that have led to the adoption of EU rules by Ukraine, despite powerful domestic vested interests and the weaknesses in EU’s policy