Crotalus ruber

Number of Pages: 17Integrative BiologyGeological Science

Bacterial Ecology of Strip Mine Areas and Its Relationship to the Production of Acidic Mine Drainage

Author Institution: Department of Microbiology, The Ohio State UniversityDUGAN, PATRICK R. Bacterial ecology of strip mine areas and its relationship to the production of acidic mine drainage. Ohio J. Sci. 75(6): 266, 1975

Reduction of leukocyte microvascular adherence and preservation of blood-brain barrier function by superoxide-lowering therapies in a piglet model of neonatal asphyxia

Background: Asphyxia is the most common cause of brain damage in newborns. Substantial evidence indicates that leukocyte recruitment in the cerebral vasculature during asphyxia contributes to this damage. We tested the hypothesis that superoxide radical (O2⋅_) promotes an acute post-asphyxial inflammatory response and blood-brain barrier (BBB) breakdown. We investigated the effects of removing O2⋅_ by superoxide dismutase (SOD) or C3, the cell-permeable SOD mimetic, in protecting against asphyxia-related leukocyte recruitment. We also tested the hypothesis that xanthine oxidase activity is one source of this radical.Methods: Anesthetized piglets were tracheostomized, ventilated, and equipped with closed cranial windows for the assessment of post-asphyxial rhodamine 6G-labeled leukocyte-endothelial adherence and microvascular permeability to sodium fluorescein in cortical venules. Asphyxia was induced by discontinuing ventilation. SOD and C3 were administered by cortical superfusion. The xanthine oxidase inhibitor oxypurinol was administered intravenously.Results: Leukocyte-venular adherence significantly increased during the initial 2 h of post-asphyxial reperfusion. BBB permeability was also elevated relative to non-asphyxial controls. Inhibition of O2⋅_ production by oxypurinol, or elimination of O2⋅_ by SOD or C3, significantly reduced rhodamine 6G-labeled leukocyte-endothelial adherence and improved BBB integrity, as measured by sodium fluorescein leak from cerebral microvessels.Conclusion: Using three different strategies to either prevent formation or enhance elimination of O2⋅_ during the post-asphyxial period, we saw both reduced leukocyte adherence and preserved BBB function with treatment. These findings suggest that agents which lower O2⋅_ in brain may be attractive new therapeutic interventions for the protection of the neonatal brain following asphyxia

Rotational and vibrational effects in ion- dipole collisions

Rotational and vibration effects in ion dipole collisions demonstrated in color motion pictur

The XV-15 tilt rotor research aircraft

The design characteristics of the XV-15 Tilt rotor research aircraft are presented. Particular attention is given to the following: control system; conversion system; and propulsion system. Flight test results are also reported

A piloted simulator study on augmentation systems to improve helicopter flying qualities in terrain flight

Four basic single-rotor helicopters, one teetering, on articulated, and two hingeless, which were found to have a variety of major deficiencies in a previous fixed-based simulator study, were selected as baseline configurations. The stability and control augmentation systems (SCAS) include simple control augmentation systems to decouple pitch and yaw responses due to collective input and to quicken the pitch and roll control responses; SCAS of rate-command type designed to optimize the sensitivity and damping and to decouple the pitch-roll due to aircraft angular tate; and attitude-command type SCAS. Pilot ratings and commentary are presented as well as performance data related to the task. SCAS control usages and their gain levels associated with specific rotor types are also discussed

A comparison of the middle English Ywain and Gawain with its old French source

The purpose of this study is to examine the differences between the Middle English romance, Ywain and Gawain, and its Old French source, Chretien de Troyes\u27 Yvain. Changes made by the English author prove that he was not merely translating Chretian\u27s work, but also adapting it to his own purposes, and can thereby be considered a poet in his own right