25 research outputs found
Timing is everything, but does it really matter? Impact of 8-weeks morning versus evening iron supplementation in ballet and contemporary dancers
The effectiveness of a morning versus evening oral iron supplement strategy to increase iron stores was explored. Ballet and contemporary dancers with serum ferritin (sFer) \u3c 50 g/L (n = 14), were supplemented daily with 105 mg elemental oral iron in either the morning (FeAM) or evening (FePM) for 8 weeks. A control group (n = 6) with sFer \u3e 50 g/L were given no supplement over the same period. Dancersâ sFer were measured at baseline and post-intervention. Assessment of daily training load, dietary intake, and menstruation were made. A significant interaction (p \u3c 0.001) showed the within group sFer change over the 8-week intervention in FeAM (+25.9 ± 10.5 g/L) and FePM, (+22.3 ± 13.6 g/L) was significantly different to CON (â30.17 ± 28.7 g/L; both p = 0.001). This change was not different between FeAM and FePM (p = 0.778). sFer levels within FeAM and FePM significantly increased over the 8-weeks; however, they significantly decreased in the CON group (all p \u3c 0.05). Post-intervention sFer levels were no longer different between the three groups (p \u3e 0.05). Training load, dietary intake, and number of menstrual cycles incurred were similar between FeAM and FePM (p \u3e 0.05). Oral iron supplementation in either the morning or evening appears equally effective in increasing sFer levels in dancers with sub-optimal iron status
Dietary iron and the elite dancer
Dancers are an athlete population at high risk of developing iron deficiency (ID). The aesthetic nature of the discipline means dancers potentially utilise dietary restriction to meet physique goals. In combination with high training demands, this means dancers are susceptible to problems related to low energy availability (LEA), which impacts nutrient intake. In the presence of LEA, ID is common because of a reduced mineral content within the low energy diet. Left untreated, ID becomes an issue that results in fatigue, reduced aerobic work capacity, and ultimately, iron deficient anaemia (IDA). Such progression can be detrimental to a dancerâs capacity given the physically demanding nature of training, rehearsal, and performances. Previous literature has focused on the manifestation and treatment of ID primarily in the context of endurance athletes; however, a dance-specific context addressing the interplay between dance training and performance, LEA and ID is essential for practitioners working in this space. By consolidating findings from identified studies of dancers and other relevant athlete groups, this review explores causal factors of ID and potential treatment strategies for dancers to optimise absorption from an oral iron supplementation regime to adequately support health and performance
Dietary iron and the elite dancer
Dancers are an athlete population at high risk of developing iron deficiency (ID). The aesthetic nature of the discipline means dancers potentially utilise dietary restriction to meet physique goals. In combination with high training demands, this means dancers are susceptible to problems related to low energy availability (LEA), which impacts nutrient intake. In the presence of LEA, ID is common because of a reduced mineral content within the low energy diet. Left untreated, ID becomes an issue that results in fatigue, reduced aerobic work capacity, and ultimately, iron deficient anaemia (IDA). Such progression can be detrimental to a dancerâs capacity given the physically demanding nature of training, rehearsal, and performances. Previous literature has focused on the manifestation and treatment of ID primarily in the context of endurance athletes; however, a dance-specific context addressing the interplay between dance training and performance, LEA and ID is essential for practitioners working in this space. By consolidating findings from identified studies of dancers and other relevant athlete groups, this review explores causal factors of ID and potential treatment strategies for dancers to optimise absorption from an oral iron supplementation regime to adequately support health and performance
Session II
Session 2: Poster Session 7:00-8:00pm: Enjoy some coffee and refreshments with the students of ENC 6942 Empirical Research in Composition as they present their empirical research design posters
Non-erythropoiesis stimulating agent, non-iron therapies for the management of anaemia: a protocol for a scoping review
Systematic review and metaâanalysis of intravenous iron therapy for adults with nonâanaemic iron deficiency: An abridged Cochrane review
Abstract Iron is an essential nutrient for oxygen supply and aerobic metabolism. Iron deficiency impacts cellular respiration and mitochondrial energy metabolism, which can lead to reduced skeletal muscle function and muscle mass, causing sarcopenia. Intravenous iron offers the ability to rapidly correct iron deficiency, but the functional impact on patient mental and physical health is unclear. We assessed the effects of intravenous iron therapy on physical function and quality of life in the treatment of adults with nonâanaemic iron deficiency. An update and reanalysis of a previously published Cochrane systematic review was performed to assess randomized controlled trials that compared any intravenous iron preparation with placebo in adults. The primary functional outcome measure was physical performance as defined by the trial authors. Secondary outcome measures included fatigue and qualityâofâlife scores, and adverse effects at the end of followâup. Biochemical efficacy was assessed by change in serum ferritin and haemoglobin concentration levels. Twentyâone randomized controlled trials, comprising 3514 participants, were included. Intravenous iron compared with placebo resulted in significantly increased physical function measured by mean peak oxygen consumption (mean difference [MD] 1.77 mL/kg/min, 95% confidence interval [CI] 0.57 to 2.97). An overall improvement in fatigue was seen (standardized MD 0.30, 95% CI â0.52 to â0.09) but no overall difference in quality of life (MD 0.15, 95% CI â0.01 to 0.31). Biochemically, intravenous iron resulted in improved serum ferritin (MD 245.52 Όg/L, 95% CI 152.1 to 338.9) and haemoglobin levels (MD 4.65 g/L, 95% CI 2.53 to 6.78). There was a higher risk of developing mild adverse events in the intravenous iron group compared with the placebo group (risk ratio 1.77, 95% CI 1.10 to 2.83); however, no differences were seen in serious adverse events (risk difference 0, 95% CI â0.01 to 0.01). The quality of evidence was rated âlowâ and âvery lowâ for all outcome variables, except for fatigue, mainly due to most studies being judged as having a high risk of bias. In nonâanaemic ironâdeficient adults, the use of intravenous iron compared with placebo improved physical function and reduced fatigue scores. However, we remain uncertain about the efficacy in this population due to lowâquality evidence, and there is a need for further studies to address potential impact on overall quality of life
Reversible C-C Bond Formation between Redox-Active Pyridine Ligands in Iron Complexes
This manuscript describes the formally iron(I) complexes LMeFe(Py-R)2 (LMe = bulky ÎČ-diketiminate; R = H, 4-tBu), in which the basal pyridine ligands preferentially accept significant unpaired spin density. Structural, spectroscopic, and computational studies on the complex with 4-tert-butylpyridine (tBupy) indicate that the S = 3/2 species is a resonance hybrid between descriptions as (a) high-spin iron(II) with antiferromagnetic coupling to a pyridine anion radical and (b) high-spin iron(I). When the pyridine lacks the protection of the tert-butyl group, it rapidly and reversibly undergoes radical coupling reactions that form new CâC bonds. In one reaction, the coordinated pyridine couples to triphenylmethyl radical, and in another, it dimerizes to give a pyridine-derived dianion that bridges two iron(II) ions. The rapid, reversible CâC bond formation in the dimer stores electrons from the formally reduced metal as a CâC bond in the ligands, as demonstrated by using the coupled diiron(II) complex to generate products that are known to come from iron(I) precursors. [from publisher\u27s website]
Synthesis, Spectroscopy, and Hydrogen/Deuterium Exchange in High-Spin Iron(II) Hydride Complexes
Very
few hydride complexes are known in which the metals have a
high-spin electronic configuration. We describe the characterization
of several high-spin ironÂ(II) hydride/deuteride isotopologues and
their exchange reactions with one another and with H<sub>2</sub>/D<sub>2</sub>. Though the hydride/deuteride signal is not observable in NMR spectra,
the choice of isotope has an influence on the chemical shifts of distant
protons in the dimers through the paramagnetic isotope effect on chemical
shift. This provides the first way to monitor the exchange of H and
D in the bridging positions of these hydride complexes. The rate of
exchange depends on the size of the supporting ligand, and this is
consistent with the idea that H<sub>2</sub>/D<sub>2</sub> exchange
into the hydrides occurs through the dimeric complexes rather than
through a transient monomer. The understanding of H/D exchange mechanisms
in these high-spin iron hydride complexes may be relevant to postulated
nitrogenase mechanisms