Development and validation of an advanced low-order panel method

A low-order potential-flow panel code, PMARC, for modeling complex three-dimensional geometries, is currently being developed at NASA Ames Research Center. The PMARC code was derived from a code named VSAERO that was developed for Ames Research Center by Analytical Methods, Inc. In addition to modeling potential flow over three-dimensional geometries, the present version of PMARC includes several advanced features such as an internal flow model, a simple jet wake model, and a time-stepping wake model. Data management within the code was optimized by the use of adjustable size arrays for rapidly changing the size capability of the code, reorganization of the output file and adopting a new plot file format. Preliminary versions of a geometry preprocessor and a geometry/aerodynamic data postprocessor are also available for use with PMARC. Several test cases are discussed to highlight the capabilities of the internal flow model, the jet wake model, and the time-stepping wake model

Fundamental noise limitations to supercontinuum generation in microstructure fiber

Broadband noise on supercontinuum spectra generated in microstructure fiber is shown to lead to amplitude fluctuations as large as 50 % for certain input laser pulse parameters. We study this noise using both experimental measurements and numerical simulations with a generalized stochastic nonlinear Schroedinger equation, finding good quantitative agreement over a range of input pulse energies and chirp values. This noise is shown to arise from nonlinear amplification of two quantum noise inputs: the input pulse shot noise and the spontaneous Raman scattering down the fiber.Comment: 16 pages with 6 figure

Potential flow theory and operation guide for the panel code PMARC

The theoretical basis for PMARC, a low-order potential-flow panel code for modeling complex three-dimensional geometries, is outlined. Several of the advanced features currently included in the code, such as internal flow modeling, a simple jet model, and a time-stepping wake model, are discussed in some detail. The code is written using adjustable size arrays so that it can be easily redimensioned for the size problem being solved and the computer hardware being used. An overview of the program input is presented, with a detailed description of the input available in the appendices. Finally, PMARC results for a generic wing/body configuration are compared with experimental data to demonstrate the accuracy of the code. The input file for this test case is given in the appendices

Men’s Perspectives of a Gender-Sensitized Health Promotion Program Targeting Healthy Eating, Active Living, and Social Connectedness

© The Author(s) 2018. Men in high income countries have poorer dietary habits and higher rates of overweight and obesity than women. A major challenge with engaging men in health promotion is the perception that attention to one’s health runs counter to masculine identities. Contemporary health promotion programs are believed to hold little “manly” appeal and often fail to engage and retain men. The HAT TRICK program was designed to engage men with their health by delivering an intervention in collaboration with a semi-professional ice hockey team. The program included 12 weekly sessions promoting healthy eating, active living, and social connectedness among men. Gender-sensitized elements were reflected in the program design, setting, content, and delivery. Semistructured telephone interviews were conducted with 23 men to explore perspectives of their participation in the gender-sensitized intervention. Participants were white (100%) with a mean age of 53 years (SD ± 9.9), Body Mass Index (BMI) of 37 kg/m2 (SD ± 6.8), and waist circumference of 127 centimeters (SD ± 14.5). Inductive thematic analysis revealed three overarching themes, including: (a) Harnessing nostalgia for past masculinities: “Closet athletes from 30 years ago,” (2) Offsetting resistance to change with sensible health advice: “Don’t give up drinking beer, just have less,” and (3) Gendered social spaces for doing health: “A night out with the guys,” The findings support the value of gender-sensitized approaches to men’s health promotion. Further research is needed to identify which gender-sensitized elements are critical to engaging men in healthy lifestyle changes

Observation of a Turbulence-Induced Large Scale Magnetic Field

An axisymmetric magnetic field is applied to a spherical, turbulent flow of liquid sodium. An induced magnetic dipole moment is measured which cannot be generated by the interaction of the axisymmetric mean flow with the applied field, indicating the presence of a turbulent electromotive force. It is shown that the induced dipole moment should vanish for any axisymmetric laminar flow. Also observed is the production of toroidal magnetic field from applied poloidal magnetic field (the omega-effect). Its potential role in the production of the induced dipole is discussed.Comment: 5 pages, 4 figures Revisions to accomodate peer-reviewer concerns; changes to main text including simplification of a proof, Fig. 2 updated, and minor typos and clarifications; Added refrences. Resubmitted to Phys. Rev. Let

Intermittent magnetic field excitation by a turbulent flow of liquid sodium

The magnetic field measured in the Madison Dynamo Experiment shows intermittent periods of growth when an axial magnetic field is applied. The geometry of the intermittent field is consistent with the fastest growing magnetic eigenmode predicted by kinematic dynamo theory using a laminar model of the mean flow. Though the eigenmodes of the mean flow are decaying, it is postulated that turbulent fluctuations of the velocity field change the flow geometry such that the eigenmode growth rate is temporarily positive. Therefore, it is expected that a characteristic of the onset of a turbulent dynamo is magnetic intermittency.Comment: 5 pages, 7 figure

Temporin A and Bombinin H2 antimicrobial peptides exhibit selective cytotoxicity to lung cancer cells

Background. Recently, antimicrobial peptides (AMPs) have been investigated for their use in cancer therapy. They have been reported to selectively target and kill cancer cells whilst leaving normal healthy cells unaffected. Certain Anura AMPs have expressed selective cytotoxicity against tumour cells. Aim. To test the potential of Anura AMPs bombinin H2, bombinin H4, temporin A, and temporin L for use as therapeutic agents for non-small cell lung carcinoma (NSCLC). Methods. Cytotoxic effects on NSCLC cell lines A549 and Calu-3 and normal epithelial cell line Beas-2B were tested using the CellTox Green Cytotoxicity Assay. Their haemolytic effects on human erythrocytes were also tested for their clinical relevance. Cell membrane profiling, using MALDI-TOF, was performed to ascertain if membrane characteristics of the NSCLC and Beas-2B cell lines may contribute to the AMPs mode of action. Results. Bombinin H4 (100-1.5 μM, p<0.05) and temporin A (100-50 μM, p<0.05) showed selective cytotoxicity towards the NSCLC cell lines. Furthermore, they exhibited low levels of haemolytic activity (bombinin H4, 0.061%; temporin A, 0.874%) comparable to untreated cells. Cell membrane profiling showed the phospholipid composition of normal epithelial cell line Beas-2B to be divergent from the cancerous cell lines. However, there was an overlap in the phospholipid profiles of the NSCLC cell lines supporting the hypothesis that the AMPs may have a selective affinity via the membrane composition of cancerous cell lines. Conclusion. These results suggest that bombinin H4 and temporin A show potential for application in lung cancer therapies. Further in vitro and in vivo studies are required to develop a greater understanding of their use as anticancer agents

Bounds on the heat kernel of the Schroedinger operator in a random electromagnetic field

We obtain lower and upper bounds on the heat kernel and Green functions of the Schroedinger operator in a random Gaussian magnetic field and a fixed scalar potential. We apply stochastic Feynman-Kac representation, diamagnetic upper bounds and the Jensen inequality for the lower bound. We show that if the covariance of the electromagnetic (vector) potential is increasing at large distances then the lower bound is decreasing exponentially fast for large distances and a large time.Comment: some technical improvements, new references, to appear in Journ.Phys.