O ESTATUTO DA PESSOA COM DEFICIÊNCIA E O NOVO CPC

Este trabalho de pesquisa consiste em analisar a Lei nº 13.146/2015, Estatuto da Pessoa com Deficiência, a partir do que diz o novo CPC quanto à questão da autonomia da vontade, o regime de incapacidades e as interdições. Os objetivos específicos compreendem: discutir brevemente a questão doutrinária em relação ao conceito histórico das pessoas com deficiência, enfatizando alguns aspectos do instituto da interdição; analisar conceitualmente a incapacidade absoluta e relativa previstas no CC/02; mostrar as principais críticas relacionadas ao regime da capacidade de exercício da pessoa com deficiência mental ou intelectual. O Estatuto baseia-se na Convenção sobre os Direitos das Pessoas com Deficiência, comumente conhecida como Convenção de New York e incorporada no ordenamento jurídico brasileiro com a finalidade precípua de inovar ao garantir a plena participação da pessoa com deficiência na sociedade. É notório que a intenção do legislador consistiu em amparar todas as espécies de deficiência, inovando nas questões e problemas relacionados à ordem psicológica. Assim, visando responder ao questionamento de quais os impactos que a Lei nº 13.146/2015, Estatuto da Pessoa com Deficiência, traz em face do novo CPC, no que diz respeito à questão da autonomia da vontade e o regime de incapacidade, optou-se pelo caminho metodológico da pesquisa bibliográfica, através do emprego da técnica descritiva; tendo como fontes utilizadas as secundárias de estudos já feitos, bem como a legislação pertinente, quando se contemplou discussões de doutrinadores e estudiosos na temática, com a intenção de chegar a uma conclusão ampliada sobre o tema

Representações sociais elaborada pela mídia sobre diabetes infantil

Objective: To understand the social representations produced by the media about childhood diabetes. Method: Study of social representations with documental basis. The search for news was carried out in two newspapers from Ceará - Diário do Nordeste and O Povo - and in two printed magazines: Veja and IstoÉ. Results: 19 news items were identified. The textual content resulting from the news was processed and analyzed through the IRAMUTEQ software. Descending Hierarchical Classification (DHC) divided the set of journalistic contents into six classes, named according to their content. Conclusion: The media uses different approaches to represent the same social phenomenon, affecting the way of production and/or modification of how society confronts the phenomena of daily life and the way it interprets them.Objetivo: Identificar las representaciones sociales producidas por los medios de comunicación acerca de la diabetes infantil. Método: Estudio de las representaciones sociales con base documental. La búsqueda de materiales se llevó a cabo en dos periódicos cearenses: Jornal Diário do Nordeste y el diario O Povo, y en dos revistas impresas: Veja e IstoÉ. Resultados: Se identificaron 19 artículos periodísticos. El contenido textual procedente de los reportajes periodísticos fue procesado y analizado por el software IRAMUTEQ. La clasificación Jerárquica Descendente (CJD) dividió el conjunto de contenidos de las noticias en seis clases, nombrados según su contenido. Conclusión: Los medios de comunicación hacen uso de diferentes enfoques para representar el mismo fenómeno social, lo que repercute en el modo de producción y / o modificación de cómo la sociedad se enfrenta a los fenómenos cotidianos y la forma cómo los interpreta.Objetivo: Apreender as representações sociais produzidas pela mídia sobre o diabetes infantil. Método: Estudo de representações sociais com base documental. A busca por matérias foi realizada em dois jornais cearenses: Jornal Diário do Nordeste e Jornal O Povo, e em duas revistas impressas: Veja e IstoÉ. Resultados: Foram identificadas 19 matérias jornalísticas. O conteúdo textual decorrente das reportagens jornalísticas foi processado e analisado por meio do software IRAMUTEQ. A Classificação Hierárquica Descentemente (CHD) dividiu o conjunto de conteúdos das matérias jornalísticas em seis classes, nomeados conforme seu conteúdo. Conclusão: A mídia faz uso de diferentes abordagens ao representarem o mesmo fenômeno social, repercutindo no modo de produção e/ou modificação de como a sociedade confronta os fenômenos do cotidiano e a forma como os interpreta

Betanin loaded nanocarriers based on quinoa seed 11S globulin. Impact on the protein structure and antioxidant activity

The objective of the present contribution was to design and characterize betanin (Bt) loaded in a nanovehicle of 11S quinoa seed protein. 11S was isolated from quinoa seed floor. Protein purification was performed by Size-Exclusion Chromatography. MALDI-TOF (Matrix-Assisted Laser Desorption/Ionization-Time-Of- Flight) analysis confirmed the identity of 11S. Nanocarriers (11S-Bt) were generated at pH 8 at different ionic strength. Globulin intrinsic fluorescence spectra showed a quenching effect exerted by Bt, demonstrating in turn protein-bioactive interaction. Stern-Volmer and Scatchard models application confirmed static quenching and allow obtaining parameters that described 11S and betanincomplexation process. Bt-11S globulin interactions seem to be more probably of physical type. Protein solubility was increased after complexation with Bt. 11S betanin-loaded nanocarrier showed additive effect in terms of both, antiradical or reducing power capacity in comparison to Bt as evaluated by two methods, 2,2 -azino-bis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS), and by ferric reducing antioxidant power (FRAP). Interestingly 11S globulin quaternary structure was modified by the bioactive, experimenting hexamer dissociation. This nanocolloid could have the potentiality to exert the Bt controlled delivery for pharmaceutical and nutraceutical products. Bt could also be protected from light and oxygen in such systems.Fil: Martínez, María Jimena. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Velázquez Duarte, Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Burrieza, Hernán Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Biodiversidad y Biología Experimental y Aplicada. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Biodiversidad y Biología Experimental y Aplicada; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental; ArgentinaFil: Martínez, Karina Dafne. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Industrias. Instituto de Tecnología de Alimentos y Procesos Químicos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Tecnología de Alimentos y Procesos Químicos; ArgentinaFil: Domínguez Rubio, Ana Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; ArgentinaFil: dos Santos Ferreira, Cristina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Orgánica; ArgentinaFil: del Pilar Buera, María. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Industrias. Instituto de Tecnología de Alimentos y Procesos Químicos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Tecnología de Alimentos y Procesos Químicos; ArgentinaFil: Perez, Oscar Edgardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina. Universidad Nacional de Lanús; Argentin

“They kicked me out of my house, I started working on the street”: intersectionality and occupational apartheid in sex work. A case study

Introduction: Women who have engaged in sex work have been a stigmatized, marginalized, and socially alienated community. Particularly, in the case of trans women, there is a bigger percentage of violence. Objective: To analyze the life story of a trans woman who works in sex work, based on an intersectional and occupational analysis. Method: We used a qualitative study based on the Life History research technique, considering elements of the occupational narrative interview. Results: From her history, we can see that there are elements that have intersected throughout her life, such as the domains: structural, disciplinary, hegemonic, and interpersonal. And that her occupational choices have been strongly influenced by her context within occupational apartheid, seeking to generate spaces of resistance and agency in the face of different adversities. Conclusions: These situations make her living conditions precarious and alert the influences of economic, political, and heteronormative systems, among others, in determining people's lives

Aspectos sociais e culturais envolvidos no processo de transição identitária da população trans

The separation between sex and gender, materialized by the notion of gender identity, was crucial to establish the needs of trans people. However, the influence of the cisnormative matrix can still be seen. Based on this premise, this study, as a qualitative research, aimed to deepen the knowledge and understanding of individual and, above all, social aspects, linked to the process of identity transition of this public, for this, an exploratory and descriptive research was carried out. Fourteen transgender people living in the city of Mossoró/RN were interviewed. Four categories of analysis were found: The fortifications of history and support, and lost basic rights, religion and affective relationships. Thus, the consequences of the imposition of heteronormativity and gender binarism in the lives of transgender people were discussed.A separação entre sexo e gênero, materializada pela noção de identidade de gênero, foi crucial para estabelecer as necessidades das pessoas trans. No entanto, vê-se ainda a influência da matriz cisnormativa. Partindo dessa premissa, esse estudo, enquanto pesquisa qualitativa, teve por objetivo aprofundar o conhecimento e o entendimento dos aspectos individuais, sobretudo, sociais, ligados ao processo de transição identitária deste público, para isso, realizou-se uma pesquisa exploratória e descritiva. Foram entrevistadas 14 pessoas transgêneros residentes no município de Mossoró/RN Encontrou-se 4 categorias de análise: As fortificações da história e do apoio e, direitos básicos perdidos, religião e relacionamentos afetivos. Assim, discutiu-se as consequências da imposição da heteronormatividade e do binarismo de gênero na vida das pessoas transgênero

The exposure to formaldehyde causes renal dysfunction, inflammation and redox imbalance in rats.

Twenty-eight Fischer male rats were divided into four groups: control group (CG), exposed to the ambient air, and groups exposed to formaldehyde (FA) at concentrations of 1% (FA1%), 5% (FA5%) and 10% (FA10%). Kidney function was assessed by dosage of uric acid, creatinine and urea. Morphometry was performed on the thickness of the lumen of Bowman's capsule and diameter of the lumen of the renal tubules. We evaluated the redox imbalance through the catalase and superoxide dismutase activity as well as oxidative damage by lipid peroxidation. Inflammatory chemokines CCL2, CCL3 and CCL5 were analyzed by enzyme immunoassays. There was an increase in the concentration of urea in FA10% compared with CG and FA1%. The levels of creatinine, renal lumen and lipid peroxidation increased in all FA-treated groups compared with CG. The concentration of uric acid in FA10% was lower compared with all other groups. There was an increase in the space of Bowman's capsule in FA5% and FA10% compared with CG and FA1%. However, the superoxide dismutase activity was higher in FA5% compared with other groups while CCL5 was higher in FA1% compared with CG. The exposure to formaldehyde in a short period of time leads to changes in the kidney function, inflammation and morphology, as well as promoted the increase of superoxide dismutase activity and oxidative damage

Serviços de atenção básica frente à pandemia de covid-19 / Basic care services in front of the covid-19 pandemic

Objetivo: analisar a literatura científica acerca do papel dos serviços de atenção básica frente à pandemia da COVID-19. Método: trata-se de uma revisão integrativa, realizada no período de outubro e novembro de 2020, a partir de fontes secundárias, selecionadas nas bases de dados da MEDLINE, LILACS, BVS, PUBMED e SciELO. Os dados obtidos foram organizados em quadro e fluxograma. Resultados: Dos treze artigos selecionados para este estudo, 100% dos artigos foram publicados em 2020, sendo 69% em periódicos internacionais e 31% em periódicos nacionais. Em relação à base de dados/ biblioteca virtual selecionada, 92% dos artigos podem ser encontrados na BVS, 42% na SciElo e 8% na PubMed. Conclusão: O papel dos serviços de atenção básica frente à pandemia do COVID-19 consiste em monitorar, notificar e fornecer dados sobre a doença. Devendo agir com rapidez na detecção dos sintomas e encaminhamento dos pacientes que ocasionalmente evoluem de uma infecção leve ou moderada para grave, para unidades hospitalares de referência.

Rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART): Study protocol for a randomized controlled trial

Background: Acute respiratory distress syndrome (ARDS) is associated with high in-hospital mortality. Alveolar recruitment followed by ventilation at optimal titrated PEEP may reduce ventilator-induced lung injury and improve oxygenation in patients with ARDS, but the effects on mortality and other clinical outcomes remain unknown. This article reports the rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART). Methods/Design: ART is a pragmatic, multicenter, randomized (concealed), controlled trial, which aims to determine if maximum stepwise alveolar recruitment associated with PEEP titration is able to increase 28-day survival in patients with ARDS compared to conventional treatment (ARDSNet strategy). We will enroll adult patients with ARDS of less than 72 h duration. The intervention group will receive an alveolar recruitment maneuver, with stepwise increases of PEEP achieving 45 cmH(2)O and peak pressure of 60 cmH2O, followed by ventilation with optimal PEEP titrated according to the static compliance of the respiratory system. In the control group, mechanical ventilation will follow a conventional protocol (ARDSNet). In both groups, we will use controlled volume mode with low tidal volumes (4 to 6 mL/kg of predicted body weight) and targeting plateau pressure <= 30 cmH2O. The primary outcome is 28-day survival, and the secondary outcomes are: length of ICU stay; length of hospital stay; pneumothorax requiring chest tube during first 7 days; barotrauma during first 7 days; mechanical ventilation-free days from days 1 to 28; ICU, in-hospital, and 6-month survival. ART is an event-guided trial planned to last until 520 events (deaths within 28 days) are observed. These events allow detection of a hazard ratio of 0.75, with 90% power and two-tailed type I error of 5%. All analysis will follow the intention-to-treat principle. Discussion: If the ART strategy with maximum recruitment and PEEP titration improves 28-day survival, this will represent a notable advance to the care of ARDS patients. Conversely, if the ART strategy is similar or inferior to the current evidence-based strategy (ARDSNet), this should also change current practice as many institutions routinely employ recruitment maneuvers and set PEEP levels according to some titration method.Hospital do Coracao (HCor) as part of the Program 'Hospitais de Excelencia a Servico do SUS (PROADI-SUS)'Brazilian Ministry of Healt

Political parties and congressional processes in Spain. An approach from participant observation and political communication to the Congresses of PSOE and Podemos.

El funcionamiento de los partidos políticos, sus asambleas y elecciones internas se han ido adaptando a las nuevas formas de comunicación política y al establecimiento de la campaña permanente. Los procesos congresuales, si bien se conciben como una fórmula para reflexionar sobre el funcionamiento de las organizaciones, también se diseñan como eventos con los que fidelizar lealtades y posibilitar el encuentro entre militantes. Así, y en términos de estrategia, movilización de afiliados y comunicación interna guardan similitudes con los periodos electorales en cuanto a visibilidad mediática e importancia organizativa en parte por su capacidad para condicionar el funcionamiento de las organizaciones en periodos entre elecciones. En el siguiente artículo se presentan los resultados de realizar observación participante en los congresos nacionales para la elección de líderes y programas en dos de los principales partidos políticos en España: PSOE y Podemos. El objetivo reside en comprender e identificar las motivaciones de los participantes compartiendo su medio natural así como el desarrollo de estos eventos desde la perspectiva de la comunicación política. Como conclusión, el artículo expone las dificultades halladas para la aplicación de este tipo de metodología, así como la identificación de estos congresos como eventos culturales, de “ocio político” y mediáticos.Inner workings of political parties, assemblies and internal elections have been adapted to new forms of political communication and the establishment of the permanent campaign. Despite of being conceived as a formula to reflect on the internal operations of organizations, congressional processes are also designed as events where the electorate meets and loyalizes with the party and its leader. Thus, affiliate mobilization and internal communication bear similarities with the electoral periods in terms of media visibility and organizational importance. In terms of strategy, this is due to their ability to condition the functioning of organizations in periods between elections. The following article presents the results of participant observation in national congresses for the election of leaders and programs in PSOE and Podemos. The main objective is to identify the motivations of the participants by sharing their natural environment. Another purpose is to understand the development of these events from the perspective of political communication. This investigation exposes the difficulties encountered for the application of this type of methodology as well as the identification of these congresses as cultural exhibitions, “political leisure” activities and media events