148 research outputs found

    PIZZA: A Powerful Image-only Zero-Shot Zero-CAD Approach to 6 DoF Tracking

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    Estimating the relative pose of a new object without prior knowledge is a hard problem, while it is an ability very much needed in robotics and Augmented Reality. We present a method for tracking the 6D motion of objects in RGB video sequences when neither the training images nor the 3D geometry of the objects are available. In contrast to previous works, our method can therefore consider unknown objects in open world instantly, without requiring any prior information or a specific training phase. We consider two architectures, one based on two frames, and the other relying on a Transformer Encoder, which can exploit an arbitrary number of past frames. We train our architectures using only synthetic renderings with domain randomization. Our results on challenging datasets are on par with previous works that require much more information (training images of the target objects, 3D models, and/or depth data). Our source code is available at https://github.com/nv-nguyen/pizzaComment: 3DV Ora

    Avatars Grow Legs: Generating Smooth Human Motion from Sparse Tracking Inputs with Diffusion Model

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    With the recent surge in popularity of AR/VR applications, realistic and accurate control of 3D full-body avatars has become a highly demanded feature. A particular challenge is that only a sparse tracking signal is available from standalone HMDs (Head Mounted Devices), often limited to tracking the user's head and wrists. While this signal is resourceful for reconstructing the upper body motion, the lower body is not tracked and must be synthesized from the limited information provided by the upper body joints. In this paper, we present AGRoL, a novel conditional diffusion model specifically designed to track full bodies given sparse upper-body tracking signals. Our model is based on a simple multi-layer perceptron (MLP) architecture and a novel conditioning scheme for motion data. It can predict accurate and smooth full-body motion, particularly the challenging lower body movement. Unlike common diffusion architectures, our compact architecture can run in real-time, making it suitable for online body-tracking applications. We train and evaluate our model on AMASS motion capture dataset, and demonstrate that our approach outperforms state-of-the-art methods in generated motion accuracy and smoothness. We further justify our design choices through extensive experiments and ablation studies.Comment: CVPR 2023, project page: https://dulucas.github.io/agrol

    Coupled analysis of non-contacting profiled finger seals taking into account friction effects

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    A computational model for coupled fluid-structure interaction analysis taking into account friction contacts is developed to study lifting capability and leakage performance of non-contacting finger seals. A cyclic finger seal segment consisting of one low-pressure finger, halves of two high-pressure fingers, front and back plates is considered. Compressible air flow in the finger seal is modeled using a computational fluid dynamics approach. A non-linear three-dimensional solid model takes into account friction contacts between the fingers and seal plates

    Multi-channel quantum noise suppression and phase-sensitive modulation in a hybrid optical resonant cavity system

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    Quantum noise suppression and phase-sensitive modulation of continuously variable in vacuum and squeezed fields in a hybrid resonant cavity system are investigated theoretically. Multiple dark windows similar to electromagnetic induction transparency (EIT) are observed in quantum noise fluctuation curve. The effects of pumping light on both suppression of quantum noise and control the widths of dark windows are carefully analyzed, and the saturation point of pumping light for nonlinear crystal conversion is obtained. We find that the noise suppression effect is strongly sensitive to the pumping light power. The degree of noise suppression can be up to 13.9 dB when the pumping light power is 6.5 Beta_th. Moreover, a phase-sensitive modulation scheme is demonstrated, which well fills the gap that multi-channel quantum noise suppression is difficult to realize at the quadrature amplitude of squeezed field. Our result is meaningful for various applications in precise measurement physics, quantum information processing and quantum communications of system-on-a-chip

    PACE Solver Description: Hust-Solver - A Heuristic Algorithm of Directed Feedback Vertex Set Problem

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    A directed graph is formed by vertices and arcs from one vertex to another. The feedback vertex set problem (FVSP) consists in making a given directed graph acyclic by removing as few vertices as possible. In this write-up, we outline the core techniques used in the heuristic feedback vertex set algorithm, submitted to the heuristic track of the 2022 PACE challenge

    Regression of Gastric Cancer by Systemic Injection of RNA Nanoparticles Carrying Both Ligand and siRNA

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    Gastric cancer is the second leading cause of cancer-related death worldwide. RNA nanotechnology has recently emerged as an important field due to recent finding of its high thermodynamic stability, favorable and distinctive in vivo attributes. Here we reported the use of the thermostable three-way junction (3WJ) of bacteriophage phi29 motor pRNA to escort folic acid, a fluorescent image marker and BRCAA1 siRNA for targeting, imaging, delivery, gene silencing and regression of gastric cancer in animal models. In vitro assay revealed that the RNA nanoparticles specifically bind to gastric cancer cells, and knock-down the BRCAA1 gene. Apoptosis of gastric cancer cells was observed. Animal trials confirmed that these RNA nanoparticles could be used to image gastric cancer in vivo, while showing little accumulation in crucial organs and tissues. The volume of gastric tumors noticeably decreased during the course of treatment. No damage to important organs by RNA nanoparticles was detectible. All the results indicated that this novel RNA nanotechnology can overcome conventional cancer therapeutic limitations and opens new opportunities for specific delivery of therapeutics to stomach cancer without damaging normal cells and tissues, reduce the toxicity and side effect, improve the therapeutic effect, and exhibit great potential in clinical tumor therapy

    Climate change : strategies for mitigation and adaptation

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    The sustainability of life on Earth is under increasing threat due to humaninduced climate change. This perilous change in the Earth's climate is caused by increases in carbon dioxide and other greenhouse gases in the atmosphere, primarily due to emissions associated with burning fossil fuels. Over the next two to three decades, the effects of climate change, such as heatwaves, wildfires, droughts, storms, and floods, are expected to worsen, posing greater risks to human health and global stability. These trends call for the implementation of mitigation and adaptation strategies. Pollution and environmental degradation exacerbate existing problems and make people and nature more susceptible to the effects of climate change. In this review, we examine the current state of global climate change from different perspectives. We summarize evidence of climate change in Earth’s spheres, discuss emission pathways and drivers of climate change, and analyze the impact of climate change on environmental and human health. We also explore strategies for climate change mitigation and adaptation and highlight key challenges for reversing and adapting to global climate change

    Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial

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    Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049
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