Dust detection by the wave instrument on STEREO: nanoparticles picked up by the solar wind?

The STEREO/WAVES instrument has detected a very large number of intense voltage pulses. We suggest that these events are produced by impact ionisation of nanoparticles striking the spacecraft at a velocity of the order of magnitude of the solar wind speed. Nanoparticles, which are half-way between micron-sized dust and atomic ions, have such a large charge-to-mass ratio that the electric field induced by the solar wind magnetic field accelerates them very efficiently. Since the voltage produced by dust impacts increases very fast with speed, such nanoparticles produce signals as high as do much larger grains of smaller speeds. The flux of 10-nm radius grains inferred in this way is compatible with the interplanetary dust flux model. The present results may represent the first detection of fast nanoparticles in interplanetary space near Earth orbit.Comment: In press in Solar Physics, 13 pages, 5 figure

Modifying effect of dual antiplatelet therapy on incidence of stent thrombosis according to implanted drug-eluting stent type

Aim To investigate the putative modifying effect of dual antiplatelet therapy (DAPT) use on the incidence of stent thrombosis at 3 years in patients randomized to Endeavor zotarolimus-eluting stent (E-ZES) or Cypher sirolimus-eluting stent (C-SES). Methods and results Of 8709 patients in PROTECT, 4357 were randomized to E-ZES and 4352 to C-SES. Aspirin was to be given indefinitely, and clopidogrel/ticlopidine for ≥3 months or up to 12 months after implantation. Main outcome measures were definite or probable stent thrombosis at 3 years. Multivariable Cox regression analysis was applied, with stent type, DAPT, and their interaction as the main outcome determinants. Dual antiplatelet therapy adherence remained the same in the E-ZES and C-SES groups (79.6% at 1 year, 32.8% at 2 years, and 21.6% at 3 years). We observed a statistically significant (P = 0.0052) heterogeneity in treatment effect of stent type in relation to DAPT. In the absence of DAPT, stent thrombosis was lower with E-ZES vs. C-SES (adjusted hazard ratio 0.38, 95% confidence interval 0.19, 0.75; P = 0.0056). In the presence of DAPT, no difference was found (1.18; 0.79, 1.77; P = 0.43). Conclusion A strong interaction was observed between drug-eluting stent type and DAPT use, most likely prompted by the vascular healing response induced by the implanted DES system. These results suggest that the incidence of stent thrombosis in DES trials should not be evaluated independently of DAPT use, and the optimal duration of DAPT will likely depend upon stent type (Clinicaltrials.gov number NCT00476957

The Feasibility of Launching Small Satellites with a Light Gas Gun

This paper summarizes a study conducted for the Defense Advanced Research Projects Agency of the technical and economic feasibility of using a light gas gun to launch small satellites. The launcher concept is based upon a distributed-injection gun, which, in principle, can produce high muzzle velocities at relatively low acceleration levels. To establish initial system requirements for the launcher and spacecraft, the deployment of a large constellation of telecommunications satellites is chosen as a reference mission. This choice reflects the dominance of telecommunications in current commercial LEO market projections, but the results obtained for this mission are later generalized to encompass other applications. The spacecraft mass budget is most affected by large mass fraction allocations for structure and power subsystems. High acceleration loads are responsible for the increase in structural mass, and the increase in battery mass is tied to volume limitations that restrict the battery technology that can be used. The results of the financial analysis suggest that achieving a competitive specific launch cost requires a launch rate beyond current market projections. But a low-volume launch business could provide an attractive total mission cost relative to current systems

Observation of relativistic electron microbursts in conjunction with intense radiation belt whistler-mode waves

We present multi-satellite observations indicating a strong correlation between large amplitude radiation belt whistler-mode waves and relativistic electron precipitation. On separate occasions during the Wind petal orbits and STEREO phasing orbits, Wind and STEREO recorded intense whistler-mode waves in the outer nightside equatorial radiation belt with peak-to-peak amplitudes exceeding 300 mV/m. During these intervals of intense wave activity, SAMPEX recorded relativistic electron microbursts in near magnetic conjunction with Wind and STEREO. The microburst precipitation exhibits a bursty temporal structure similar to that of the observed large amplitude wave packets, suggesting a connection between the two phenomena. Simulation studies corroborate this idea, showing that nonlinear wave--particle interactions may result in rapid energization and scattering on timescales comparable to those of the impulsive relativistic electron precipitation.Comment: This paper has been withdrawn by the author

Equal Access Is Quality: an Update on the State of Disparities Research in Trauma

Purpose of Review: Over the past 5 years, disparities in the access to and quality of trauma care have expanded on the relatively nascent body of literature. Recent Findings: This review summarizes the newest findings in trauma disparities research, identifying 47 original research articles that either illuminate disparities that had not been previously described or augment our understanding of a known disparity. Furthermore, the current literature on trauma disparities establishes the importance of investigating disparities in pre and post-hospital quality metrics and refining the approach to quality measurement for trauma care in pediatric and geriatric populations in particular. A new development on the study of trauma disparities is the effort to establish the mechanisms by which racial/ethnic and socioeconomic disparities occur. Summary: The authors conclude from this evidence-based review that, as new disparities in trauma care continue to emerge, novel approaches to measuring and eliminating these disparities are needed