139 research outputs found

    Sustainable Retirement: A Look At Consumer Desires

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    This paper examines the findings of the research project, 'Retirement Savings: Drivers and Desires', commissioned by the Investment and Financial Services Association Ltd (IFSA) in 2001. The paper investigates retirement savings decision-making and retirement income product stream choice. This paper presents a quantitative analysis of questionnaire data relating to decision-making and product stream choice and discusses these issues in the context of established research findings about retirement income. The paper consists of five sections. The first is a brief review of the 'Drivers and Desires' research project conducted in 2001. An important theme to emerge from the initial project was that participants reported a high level of risk aversion and a strong desire to obtain the publicly funded age pension. Based on the findings of the initial project, the remaining sections of this paper focuses on consumer preferences, particularly relating to risk aversion and demand for the age pension. The second section focuses on a specific issue emanating from the initial project, specifically the market for annuities. The third section considers retirement income streams in terms of risks to investors. The fourth section carries out a quantitative analysis of consumer preferences toward the identified risks in previous sections, and specifically considers various trade-offs in the decision-making process. The fifth section outlines various policy alternatives and issues for future consideration.

    Wireless Networking

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    Requires RealPlayer to view.The University Archives has determined that this item is of continuing value to OSU's history.Presentation at Technology for the Rest of Us: What Every Librarian Should Understand about the Technologies that Affect Us, May 24-27, 2004.This project is funded in part through an Institute of Museum and Library Services LSTA grant awarded by the State Library of Ohi

    Assessment of Failure of colostral Absorption Among Well-Managed Herds Using a Simple Screening Test

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    Failure of calves to ingest colostrum early in life is associated with an increased risk of illness and death. Colostral antibody absorption can be easily estimated with a blood sample collected after the calf is 24 hours old. This study was conducted to determine the proportion of calves born at the four SDSU beef units that were affected with inadequate passive transfer (IPT) as a result of inadequate colostral antibody absorption. Of the 333 calves, 44 were affected with IPT (1 3.2%). There were significant differences in IPT between units, suggesting that environmental factors unique to each unit may have a role in contributing to IPT. Calves of first calf heifers tended to be affected with IPT in a greater proportion than calves born to cows. Females that required assistance at birth produced calves that were 2.5 times as likely to be affected with IPT as females requiring no assistance (P = .058). Calves born during the late evening hours tended to be at greater risk for IPT compared to calves born in the early morning or during the work day. The incidence of IPT appeared to vary among herds, suggesting that control of IPT is possible

    Astrometry with the Keck-Interferometer: the ASTRA project and its science

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    The sensitivity and astrometry upgrade ASTRA of the Keck Interferometer is introduced. After a brief overview of the underlying interferometric principles, the technology and concepts of the upgrade are presented. The interferometric dual-field technology of ASTRA will provide the KI with the means to observe two objects simultaneously, and measure the distance between them with a precision eventually better than 100 uas. This astrometric functionality of ASTRA will add a unique observing tool to fields of astrophysical research as diverse as exo-planetary kinematics, binary astrometry, and the investigation of stars accelerated by the massive black hole in the center of the Milky Way as discussed in this contribution.Comment: 22 pages, 10 figures (low resolution), contribution to the summerschool "Astrometry and Imaging with the Very Large Telescope Interferometer", 2 - 13 June, 2008, Keszthely, Hungary, corrected authorlis

    Heterologous Expression and Purification Systems for Structural Proteomics of Mammalian Membrane Proteins

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    Membrane proteins (MPs) are responsible for the interface between the exterior and the interior of the cell. These proteins are implicated in numerous diseases, such as cancer, cystic fibrosis, epilepsy, hyperinsulinism, heart failure, hypertension and Alzheimer's disease. However, studies on these disorders are hampered by a lack of structural information about the proteins involved. Structural analysis requires large quantities of pure and active proteins. The majority of medically and pharmaceutically relevant MPs are present in tissues at very low concentration, which makes heterologous expression in large-scale production-adapted cells a prerequisite for structural studies. Obtaining mammalian MP structural data depends on the development of methods that allow the production of large quantities of MPs. This review focuses on the different heterologous expression systems, and the purification strategies, used to produce large amounts of pure mammalian MPs for structural proteomics

    University Reporter Issue 4

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    Alaska Methodist University Back in Business By: Jim Kelly (2) Readers/Writers By: Unknown (2) Students Speak Out: By: Unknown (2) Editorial Educational Alternatives By: Unknown (2) No One’s In Charge By: Bill Parker (3) Surviving As a Public Servant By: Gene Johnson (3) More Than 2500 UAA Students Benefit A Guide To Financial Aid By: Unknown (4) Glossary – The Language of Financial Aid By: Unknown (5) The Myth of Objectivity By: Unknown (6) Recommended Readings By: Unknown (7) LAO TZU And TAI CHI CHUAN Oriental Guide To Eternal Youth BY; Frank Marino (8) Local Doctor Says Good Health Is Simpler Than You Think A Naturopath’s Perspective By: Doris M. Williams (9) Good Food at Good Prices How To Start A Food Co-op By: Unknown (10) Free of Charge Open Door Clinic Serves Community By: Jim Kelly (10) Knowles Says ‘Deck Stacked’ in Unification Report Anchorage Government Reviewed By: Tony Knowles (11) Student Challenges Professional Medical Establishment Health care For People Not Profit By: Megan Andersen (12) Women Alive! By: Sue Drew (14) Hormone Cycles By: Unknown (14) One Proud Homeowner’s Story Anchorage Tipi Dwellers Live Close To The Land By: Jim Ellis (15) A Meditation For Survival By: Nirvair Singh Gibbs (17) ACC Teacher & Student Tackle Mt. McKinley By: Unknown (17) True Cheating By: Barbara Jackson (17) The Student Ombudsman Tell It To Ray BY: Ray Huard (18) Theatre Is a Better Way of Living Than Living Is By: Kim DeLong (18) Visual Arts Center Asks For Help By: Unknown (19) Academy Award Winner, Hearts and Minds, To Show On Campus By: Unknown (19) Majors’ to be offered Alaska Methodist University By: Unknown (20) The Mission Of AMU By: Unknown (21) Simple Guide TO Earthquake Survival By: Unknown (21) Could you be a nuclear expert? By: Unknown (21) Corrections (22) Foreign Students Must Work Hard to Survive By: Unknown (22) The Print Switchboard (23) Community Calendar (24

    The extraordinary evolutionary history of the reticuloendotheliosis viruses

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    The reticuloendotheliosis viruses (REVs) comprise several closely related amphotropic retroviruses isolated from birds. These viruses exhibit several highly unusual characteristics that have not so far been adequately explained, including their extremely close relationship to mammalian retroviruses, and their presence as endogenous sequences within the genomes of certain large DNA viruses. We present evidence for an iatrogenic origin of REVs that accounts for these phenomena. Firstly, we identify endogenous retroviral fossils in mammalian genomes that share a unique recombinant structure with REVs—unequivocally demonstrating that REVs derive directly from mammalian retroviruses. Secondly, through sequencing of archived REV isolates, we confirm that contaminated Plasmodium lophurae stocks have been the source of multiple REV outbreaks in experimentally infected birds. Finally, we show that both phylogenetic and historical evidence support a scenario wherein REVs originated as mammalian retroviruses that were accidentally introduced into avian hosts in the late 1930s, during experimental studies of P. lophurae, and subsequently integrated into the fowlpox virus (FWPV) and gallid herpesvirus type 2 (GHV-2) genomes, generating recombinant DNA viruses that now circulate in wild birds and poultry. Our findings provide a novel perspective on the origin and evolution of REV, and indicate that horizontal gene transfer between virus families can expand the impact of iatrogenic transmission events

    International society of sports nutrition position stand: tactical athlete nutrition

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    This position stand aims to provide an evidence-based summary of the energy and nutritional demands of tactical athletes to promote optimal health and performance while keeping in mind the unique challenges faced due to work schedules, job demands, and austere environments. After a critical analysis of the literature, the following nutritional guidelines represent the position of the International Society of Sports Nutrition (ISSN)

    Overcoming bottlenecks in the membrane protein structural biology pipeline

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    Membrane proteins account for a third of the eukaryotic proteome, but are greatly under-represented in the Protein Data Bank. Unfortunately, recent technological advances in X-ray crystallography and EM cannot account for the poor solubility and stability of membrane protein samples. A limitation of conventional detergent-based methods is that detergent molecules destabilize membrane proteins, leading to their aggregation. The use of orthologues, mutants and fusion tags has helped improve protein stability, but at the expense of not working with the sequence of interest. Novel detergents such as glucose neopentyl glycol (GNG), maltose neopentyl glycol (MNG) and calixarene-based detergents can improve protein stability without compromising their solubilizing properties. Styrene maleic acid lipid particles (SMALPs) focus on retaining the native lipid bilayer of a membrane protein during purification and biophysical analysis. Overcoming bottlenecks in the membrane protein structural biology pipeline, primarily by maintaining protein stability, will facilitate the elucidation of many more membrane protein structures in the near future
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