2,346 research outputs found

    Screening for antibiotic-producers in soil from a garden

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    Multidrug-resistant pathogens are the leading cause of nosocomial infection, which killed more than 30,000 people in the United States every year. Among these, ESKAPE strains bugs, which comprise six highly drug-resistant bacteria, pose the greatest challenge to the healthcare system. In order to fight the antibiotic-resistant crises, novel antibiotic-producers must be discovered. This project is a collaboration with the Tiny Earth Project Initiative (TEPI), which is a global network of educators and students focused on student sourcing antibiotic discovery from the soil. Pseudomonas was revealed to produce a zone of inhibition against Bacillus subtilis on LB media. The next step will be isolating the active antibiotic compounds and studying their mode of action

    THE IMPACT OF NATIONAL CULTURE ON BILATERAL TRADE IN VIETNAM

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    The purpose of this paper is to examine whether or to what extent national culture influences bilateral trade flows between Vietnam and its trading partners. Using a panel dataset of 52 countries from 2001 till 2011 and six cultural dimensions of Hofstede, the regression analysis performed by gravity model shows that national culture and bilateral trade flows between Vietnam and trading partners are significantly correlated. This study's implications may help macro-policy makers devise better export promotion policies and boost the volume of bilateral trade between Vietnam and other countries around the world

    Estimation of subsurface porosities and thermal conductivities of polygonal tundra by coupled inversion of electrical resistivity, temperature, and moisture content data

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    Studies indicate greenhouse gas emissions following permafrost thaw will amplify current rates of atmospheric warming, a process referred to as the permafrost carbon feedback. However, large uncertainties exist regarding the timing and magnitude of the permafrost carbon feedback, in part due to uncertainties associated with subsurface permafrost parameterization and structure. Development of robust parameter estimation methods for permafrost-rich soils is becoming urgent under accelerated warming of the Arctic. Improved parameterization of the subsurface properties in land system models would lead to improved predictions and a reduction of modeling uncertainty. In this work we set the groundwork for future parameter estimation (PE) studies by developing and evaluating a joint PE algorithm that estimates soil porosities and thermal conductivities from time series of soil temperature and moisture measurements and discrete in-time electrical resistivity measurements. The algorithm utilizes the Model-Independent Parameter Estimation and Uncertainty Analysis toolbox and coupled hydrological-thermal-geophysical modeling. We test the PE algorithm against synthetic data, providing a proof of concept for the approach. We use specified subsurface porosities and thermal conductivities and coupled models to set up a synthetic state, perturb the parameters, and then verify that our PE method is able to recover the parameters and synthetic state. To evaluate the accuracy and robustness of the approach we perform multiple tests for a perturbed set of initial starting parameter combinations. In addition, we varied types and quantities of data to better understand the optimal dataset needed to improve the PE method. The results of the PE tests suggest that using multiple types of data improve the overall robustness of the method. Our numerical experiments indicate that special care needs to be taken during the field experiment setup so that (1) the vertical distance between adjacent measurement sensors allows the signal variability in space to be resolved and (2) the longer time interval between resistivity snapshots allows signal variability in time to be resolved

    Effects of surface contamination on the interfacial properties of CO2/water/calcite systems

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    Understanding the wetting properties of reservoir rocks can be of great benefit for advanced applications such as the effective trapping and geological storage of CO2. Despite their importance, not all mechanisms responsible for wetting mineral surfaces in subsurface environments are well understood. Factors such as temperature, pressure and salinity are often studied, achieving results with little unanimity; other possible factors are left somewhat unexplored. One such factor is the effect of contamination. In the present study, the effects of adding a non-aqueous organic contaminant, ethanol, on the CO2–water interfacial tension (IFT) and the CO2/water/calcite contact angle were investigated using molecular dynamics simulations. Within the conditions studied, relatively small amounts of ethanol cause a significant decrease in the CO2–water IFTs, as well as a pronounced increase in the water-calcite-CO2 three phase contact angle. The latter result is due to the decrease of the IFT between CO2 and water and the strong adsorption of ethanol on the solid substrate. These findings could be helpful for explaining how impurities can affect experimental data and could lead to effective carbon sequestration strategies

    ANALYZING THE FACTORS AFFECTING FACIAL CLEANSER DEMAND AMONG YOUNG PEOPLE IN VIETNAM

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    The research analyzes the factors affecting the demand for made-in-Vietnam facial cleanseramong the Vietnamese youth. Based on the theory of commodity demand, the research team builds a survey form and collects responses from 415 students at high schools and universities in Vietnam on the factors affecting their demand for made-in-Vietnam facial cleansers. The synthesis and analysis of survey data show that the demand for face wash products among Vietnamese young people is influenced by many factors such as the price of the products, income, interests, prices of related goods, expectations of themarket, etc. Besides, the research team also considers the advantages of Vietnamese face wash products compared to imported products and young consumers' expectations for the products as well as their beliefs and supportfor made-in-Vietnam facial cleanser products in the future

    Robust multicolor single photon emission from point defects in hexagonal boron nitride

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    © 2017 IEEE. We demonstrates engineering of quantum emitters in hBN multi-layers using either electron beam irradiation or annealing. The defects exhibit a broad range of multicolor room-temperature single photon emissions across the visible and the near-infrared ranges

    Glycosylation characterization of therapeutic mAbs by top- and middle-down mass spectrometry

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    A reference monoclonal antibody IgG1 and a fusion IgG protein were analyzed by top- and middle-down mass spectrometry with multiple fragmentation techniques including electron transfer dissociation (ETD) and matrix-assisted laser desorption ionization in-source decay (MALDI-ISD) to investigate heterogeneity of glycosylated protein species. Specifically, glycan structure, sites, relative abundance levels, and termini structural conformation were investigated by use of Fourier transform ion cyclotron resonance (FT-ICR) or high performance liquid chromatography electrospray ionization (HPLC-ESI) linked to an Orbitrap. Incorporating a limited enzymatic digestion by immunoglobulin G-degrading enzyme Streptococcus pyogenes (IdeS) with MALDI-ISD analysis extended sequence coverage of the internal region of the proteins without pre-fractionation. The data in this article is associated with the research article published in Journal of Proteomics (Tran et al., 2015)

    An instability criterion for nonlinear standing waves on nonzero backgrounds

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    A nonlinear Schr\"odinger equation with repulsive (defocusing) nonlinearity is considered. As an example, a system with a spatially varying coefficient of the nonlinear term is studied. The nonlinearity is chosen to be repelling except on a finite interval. Localized standing wave solutions on a non-zero background, e.g., dark solitons trapped by the inhomogeneity, are identified and studied. A novel instability criterion for such states is established through a topological argument. This allows instability to be determined quickly in many cases by considering simple geometric properties of the standing waves as viewed in the composite phase plane. Numerical calculations accompany the analytical results.Comment: 20 pages, 11 figure
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