2,601 research outputs found

    Institute of Archaeology & Horn Archaeological Museum Newsletter Volume 25.4

    Get PDF
    Triennial Jordan Conference, Paul J. Ray, Jr. Tall Hisban 2004, Bethany J. Walker \u27Umayri 2004, Douglas R. Clark and Larry G. Herr Random Surveyhttps://digitalcommons.andrews.edu/iaham-news/1020/thumbnail.jp

    Evolution of a mafic volcanic field in the central Great Basin, south central Nevada

    Get PDF
    This is the published version. Copyright 2012 American Geophysical Union. All Rights Reserved.Evolution of a mafic volcanic field is investigated through a study of Pliocene age rocks in the Reveille Range in south central Nevada. Pliocene activity began with the eruption of relatively abundant hawaiite (episode 1, 5–6 Ma), which was followed by trachytic volcanism (4.3 Ma) and by a second episode of lower-volume hawaiite and basanite (episode 2, 3.0–4.7 Ma). Incompatible elements indicate an asthenospheric source. Isotopically, episode 2 basalts cluster around 87Sr/86Sr = 0.7035 and εNd = +4.2, but episode 1 samples vary to high 87Si/86Sr (up to 0.7060) over a narrow range of εNd (+0.8 to +4.5). Trachytic rocks (MgO ∼ 0.5%) are isotopically akin to the episode 1 basalts. Geochemical variation requires the addition of a crustal component (high 87Sr/86Sr, Sr/Nd, Pb/La, low εNd) to the episode 1 hawaiites and trachytic samples, probably by assimilation of carbonate-rich sedimentary wall rock. The volcanic field developed in at least two eruptive cycles of approximately equal duration. Basanites (deeper and lower percentage melts) appear only in the younger episode. Eruptive episodes were apparently linked to separate melting events in the mantle. Through time, basalts were produced in diminishing volumes by lower percentage melting, magma generation and storage was at greater depths, and magma ascent was at higher velocities. Spatially, the melting anomalies were large in the Pliocene but progressively diminished in size so that by Pleistocene time, volcanism was restricted to a small area near the northern end of the initial outbreak

    Brush Seals for Cryogenic Applications: Performance, Stage Effects, and Preliminary Wear Results in LN2 and LH2

    Get PDF
    Brush seals are compliant contacting seals and have significantly lower leakage than labyrinth seals in gas turbine applications. Their long life and low leakage make them candidates for use in rocket engine turbopumps. Brush seals, 50.8 mm (2 in.) in diameter with a nominal 127-micron (0.005-in.) radial interference, were tested in liquid nitrogen (LN2) and liquid hydrogen (LH2) at shaft speeds up to 35,000 and 65,000 rpm, respectively, and at pressure drops up to 1.21 MPa (175 psid) per brush. A labyrinth seal was also tested in liquid nitrogen to provide a baseline. The LN2 leakage rate of a single brush seal with an initial radial shaft interference of 127 micron (0.005 in.) measured one-half to one-third the leakage rate of a 12-tooth labyrinth seal with a radial clearance of 127 micron (0.005 in.). Two brushes spaced 7.21 micron (0.248 in.) apart leaked about one-half as much as a single brush, and two brushes tightly packed together leaked about three-fourths as much as a single brush. The maximum measured groove depth on the Inconel 718 rotor with a surface finish of 0.81 micron (32 microinch) was 25 micron (0.0010 in.) after 4.3 hr of shaft rotation in liquid nitrogen. The Haynes-25 bristles wore approximately 25 to 76 micron (0.001 to 0.003 in.) under the same conditions. Wear results in liquid hydrogen were significantly different. In liquid hydrogen the rotor did not wear, but the bristle material transferred onto the rotor and the initial 127 micron (0.005 in.) radial interference was consumed. Relatively high leakage rates were measured in liquid hydrogen. More testing is required to verify the leakage performance, to validate and calibrate analysis techniques, and to determine the wear mechanisms. Performance, staging effects, and preliminary wear results are presented

    Differences in Gene Expression Profiles and Phenotypes of Differentiated SH-SY5Y Neurons Stably Overexpressing Mitochondrial Ferritin

    Get PDF
    Mitochondrial ferritin (FtMt) is an iron-transport protein with ferroxidase properties localized to mitochondria. Levels are generally low in all tissues, while increasing the expression of FtMt in neuronal-like cells has been shown to be protective. To determine whether FtMt has potential as a therapeutic approach, there remains the question of how much FtMt is protective. To address this issue, we transfected SH-SY5Y neuroblastoma cells with a FtMt expression plasmid and isolated cell lines with stable expression of FtMt at high, medium and low levels. Using these cell lines, we examined effects of FtMt on neuronal phenotype, neuroprotective activity and gene expression profiles. The phenotypic properties of high, medium and low FtMt expressors were compared with native untransfected SH-SY5Y cells after differentiation with retinoic acid to a neuronal phenotype. Overexpression of FtMt, even in low expressing cells, showed significant protection from oxidative stress induced by hydrogen peroxide or cobalt chloride. Higher levels of FtMt expression did not appear to offer greater protection, and did not have toxic consequences to cells, even though there were significantly more aggregated mitochondria in the highest expressing clone. The phenotypes differed between cell clones when assessed by cell growth, neurite outgrowth, and expression of neuronal proteins including those associated with neurodegenerative diseases. Microarray analysis of high, medium and negative FtMt-expressing cells identified different patterns of expression of certain genes associated with oxidative stress and neuronal development, amongst others. Validation of microarray analyses was carried out by real time polymerase chain reaction. The results showed significant differences in expression of thioredoxin-interacting protein (TXNIP) and microsomal glutathione transfer-1 (MGST-1), which can have critical roles in the regulation of oxidative stress. Differences in expression of calcitonin-related polypeptide alpha (CALCA), growth differentiation factor-15 (GDF-15) and secretogranin II (SCG2) were also observed. Our findings indicate that even low levels of increased FtMt expression can be protective possibly by alterations of some oxidative stress-related and growth factor genes, while high levels of expression did not appear to offer greater protection from oxidative stress or induce significant toxicity in cells. These experiments provide supporting data that increasing FtMt might be a feasible strategy for therapeutics in certain neurodegenerative and neurological diseases

    The Planetary Nebulae Spectrograph: the green light for Galaxy Kinematics

    Get PDF
    Planetary nebulae are now well established as probes of galaxy dynamics and as standard candles in distance determinations. Motivated by the need to improve the efficiency of planetary nebulae searches and the speed with which their radial velocities are determined, a dedicated instrument - the Planetary Nebulae Spectrograph or PN.S - has been designed and commissioned at the 4.2m William Herschel Telescope. The high optical efficiency of the spectrograph results in the detection of typically ~ 150 PN in galaxies at the distance of the Virgo cluster in one night of observations. In the same observation the radial velocities are obtained with an accuracy of ~ 20 km/sComment: Accepted by PASP, to appear November 2002; the figures have been degraded for archival purpose

    Evolution of extensional basins and basin and range topography west of Death Valley, California

    Get PDF
    This is the published version. Copyright 2010 American Geophysical Union. All Rights Reserved.Neogene extension in the Death Valley region, SE California, has produced a variety of sedimentary basins. Diachronous movements on an array of strike-slip and normal fault systems have resulted in the uplift and preservation of older basins in modern ranges. One of the best exposed of these is the Nova basin on the western flank of the Panamint Mountains. The Nova basin includes over 2000 m of sedimentary and volcanic rocks deposited during denudation of the Panamint Mountains metamorphic core complex in late Miocene (?) – early Pliocene time. The principal growth structure for the basin was the Emigrant detachment, which initiated and moved at a low angle. Modern Panamint Valley, west of the range, developed as a consequence of Late Pliocene - Recent, kinematically linked movement on the right-slip, high-angle Hunter Mountain fault zone and the low-angle Panamint Valley detachment. Detailed mapping of the intersection between the Emigrant and Panamint Valley detachments demonstrates that segments of the earlier system remained active during development of Panamint Valley and, thus, during development of modern Basin and Range topography as well. These results indicate that large-scale extension in the Death Valley region, accommodated by movement on low- to moderate-angle normal fault systems and high-angle strike-slip fault systems, is a continuing process. Basin and Range topography in the Panamint Valley - Death Valley area was generated at least in part by displacements on low-angle detachments rather than high-angle normal faults
    • …
    corecore