20 research outputs found
Umělé smysly
PoÄŤĂtaÄŤem Ĺ™ĂzenĂ© objekty, autorskĂ˝ software/ hardware. Práce je sĂ©rie elektronickĂ˝ch objektĹŻ z kovovĂ˝ch prefabrikovanĂ˝ch komponentĹŻ. Konstrukce jsou automatizovanĂ© a reagujĂ na rĹŻznĂ© podnÄ›ty, jako jsou napĹ™Ăklad drobnĂ© tepelnĂ© nebo svÄ›telnĂ© zmÄ›ny, kterĂ© ležà na hranici vnĂmatelnosti ÄŤlovÄ›ka.Computer-controlled objects, author's software and hardware components. This work is a serie of author's objects created mainly from metal prefabricated components. Constructions are fully automatic and they react to variable stimuly like an air temperature or light intesity differences. This perceptibility lies on the border of sensitivity of human
Diversity of image and motion development
PoÄŤĂtaÄŤem Ĺ™ĂzenĂ© objekty, autorskĂ˝ kĂłd v programu Arduino a hardware. SbÄ›r dat pomocĂ elektronickĂ˝ch komponentĹŻ, zpracovávánĂ a pĹ™etvářenĂ informace pomocĂ algoritmĹŻ v robotickĂ© autonomnĂ jednotce. Práce je sĂ©rie funkÄŤnĂch elektronickĂ˝ch objektĹŻ a generovanĂ©ho obrazu v reálnĂ©m ÄŤase. InspirovanĂ˝ souÄŤasnĂ˝m trendem 3D tiskáren, CNC plotterĹŻ a tvorbou domácĂch robotĹŻ. InspiracĂ se mi stal nejen souÄŤasnĂ˝ umÄ›lec Dmitry Morozov, David Bowen ale takĂ© Petr Vogel, ZdenÄ›k Pešánek, Jean Tinguely a Frieder Nake.Computer-controlled objects, my own hardware and code programmed in Arduino. Data collection by using electronic components. Processing and transformation of information by using algorithms in a robotic autonomous unit. The work is a series of functional electronic objects and generated image (image in real time). Inspired by the current trend of 3D printers, CNC plotters, and the creation of DIY robots. I was inspired not only by contemporary artist Dmitry Morozov, David Bowen but also by Petr Vogel, ZdenÄ›k Pešánek, Jean Tinguely and Frieder Nake
The secret of dry hopped beers – review
Dry hopped beers gain their characteristic flavour from hop products purposely added during the cold stage of production. Although the production of these beers has not so broad a tradition in the Czech Republic as for instant in Great Britain or the United States, their popularity increases every year. This study provides a complete set of theoretical and practical information about the production of dry hopped beers. The relevant sensory active compounds of hops creating the characteristic beer aroma and factors influencing their transfer into beer are introduced. The last part of the study deals with some important risk factors which must be considered during the production of dry hopped beers
Classification of Czech Hops According to their Contents of Prenylflavonoids
The prenylated flavonoids are hop components with the most beneficial health effects. Information about their content and the dynamics of their decrease during hops processing is necessary for the production of beer with an increased content of these substances. This study deals with the long-term monitoring of the prenylflavonoids and α-bitter acids contents and their ratios in the whole spectrum of domestic hop varieties as well as with changes in these parameters during storage and hop processing. It was confirmed that the newly cultivated Agnus and Vital varieties are the varieties with the highest contents of prenylated flavonoids. As a result, the Vital variety is particularly useful in non-brewing applications. Based on the monitoring of the decrease in the levels of these components during hop processing it was recognised that development of new gentler methods, particularly for the hop drying would be necessary. These methods should minimize the risk of thermal and oxidative degradation
Alternative Methods for Shelf Life Extension of Unfi ltered Beers from Microbreweries
At present, a broad range of unfi ltered beers is produced mainly by microbreweries. So far, however, no suitable method exists for ensuring extended shelf life at the industrial scale without damaging the taste. The most widespread method – pasteurization also kills brewery yeasts and, has a thermal impact on beer. This review describes the premises for ensuring effective microbial stabilization that depends particularly on proper sanitization practices. Alternative methods – the high hydrostatic in addition, processing and the pulsed electric fi elds processing have a minimal effect on the beer quality. These techniques were already tested under laboratory conditions and have potential for use at the industrial scale. This article describes these methods in detail
Plasma cell-free DNA methylation analysis for ovarian cancer detection: Analysis of samples from a case-control study and an ovarian cancer screening tria
Analysis of cell-free DNA methylation (cfDNAme), alone or combined with CA125, could help to detect ovarian cancers earlier and may reduce mortality. We assessed cfDNAme in regions of ZNF154, C2CD4D and WNT6 via targeted bisulfite sequencing in diagnostic and early detection (preceding diagnosis) settings. Diagnostic samples were obtained via prospective blood collection in cell-free DNA tubes in a convenience series of patients with a pelvic mass. Early detection samples were matched case-control samples derived from the UK Familial Ovarian Cancer Screening Study (UKFOCSS). In the diagnostic set (ncases  = 27, ncontrols  = 41), the specificity of cfDNAme was 97.6% (95% CI: 87.1%-99.9%). High-risk cancers were detected with a sensitivity of 80% (56.3%-94.3%). Combination of cfDNAme and CA125 resulted in a sensitivity of 94.4% (72.7%-99.9%) for high-risk cancers. Despite technical issues in the early detection set (ncases  = 29, ncontrols  = 29), the specificity of cfDNAme was 100% (88.1%-100.0%). We detected 27.3% (6.0%-61.0%) of high-risk cases with relatively lower genomic DNA (gDNA) contamination. The sensitivity rose to 33.3% (7.5%-70.1%) in samples taken <1 year before diagnosis. We detected ovarian cancer in several patients up to 1 year before diagnosis despite technical limitations associated with archival samples (UKFOCSS). Combined cfDNAme and CA125 assessment may improve ovarian cancer screening in high-risk populations, but future large-scale prospective studies will be required to validate current findings
Short Time PID Autotuner
CĂlem tĂ©to práce je navrhnout pro systĂ©my s jednou dominantnĂ ÄŤasovou konstantou modifikaci momentovĂ©ho autotuneru, která vĂ˝raznÄ› snĂžà čas identifikaÄŤnĂho experimentu. NavrĹľená modifikace je otestována na mnoĹľinÄ› apriornÄ› pĹ™ĂpustnĂ˝ch systĂ©mĹŻ a vymezena oblast vhodnĂ©ho pouĹľitĂ tĂ©to metody. Je provedena analĂ˝za závislosti kvality identifikace na velikosti dominantnĂ ÄŤasovĂ© konstanty a jejĂ vliv na návrh PI a PID regulátoru. Dále jsou analyzovány moĹľnosti rozhodovánĂ o vhodnosti navrĹľenĂ© metody v reálnĂ©m ÄŤase v rámci samotnĂ©ho autotuneru.ObhájenoThe aim of this work is to design a modification of the moment autotuner for systems with one dominant time constant to reduce significantly the time of the identification experiment. The proposed modification is tested on a set of a priori permissible systems. Furthermore, we define the area of suitable usage of this method. The dependence of the quality of identification on the size of the dominant time constant and its influence on the design of PI and PID controllers is analysed. In addition we discuss possibilities of real-time decision-making for using the results provided by this method
Computing of process characteristic numbers from limited experimental data
CĂlem tĂ©to práce je analĂ˝za metod, kterĂ© vedou na odhad charakteristickĂ˝ch ÄŤĂsel, jimiĹľ lze aproximovat skuteÄŤnĂ˝ systĂ©m. PomocĂ momentovĂ© metody bude vygenerována rozsáhlá testovacĂ mnoĹľina, slouĹľĂcĂ k ohodnocenĂ kvality identifikace napĹ™ĂÄŤ nÄ›kolika identifikovanĂ˝mi strukturami, vstupnĂmi signály a sadou testovacĂch monotĂłnnĂch systĂ©mĹŻ. NáslednÄ› bude diskutován vliv šumu na kvalitu identifikace. SoučástĂ práce je tĂ©Ĺľ Ĺ™ešenĂ˝ pĹ™Ăklad, kterĂ˝ podchycuje základy identifikace systĂ©mĹŻ pomocĂ identifikaÄŤnĂho toolboxu v prostĹ™edĂ MATLAB.Katedra kybernetikyObhájenoThe aim of this work is to analyze methods leading up to characteristic numbers estimation. The real system can be approached due to this numbers. We will generate large test set based on the moments method to rate identification quality. For the set of systems there will be tested some of identification structures and input signals. Also the noise influence will be discussed. Part of this work provides an outline how to identify systems in MATLAB by System Identification Toolbox
Marking of axillary lymphatic nodes in breast cancer patients.
Introduction Axillary dissection has little diagnostic and therapeutic benefit in the node-positive breast cancer patients in whom axillary disease has been completely eradicated after neoadjuvant chemotherapy (ypN0). We sought to assess the efficacy of an algorithm used for the identification of the ypN0 patients consisting of intraoperative evaluation of sentinel and tattooed (initially positive) lymph nodes. Methods Included were T1 and T2 breast cancer patients with one to three positive axillary lymph nodes marked with carbon who were referred for neoadjuvant chemotherapy followed by a surgery. Axillary dissection was performed only in the patients with residual axillary disease after neoadjuvant chemotherapy on ultrasound or with metastases described in the sentinel or tattooed lymph nodes either intraoperatively or in the final histology. Results Out of 62 included initially node-positive patients, 15 (24%) were spared axillary dissection. The detection rate of tattooed lymph node after neoadjuvant chemotherapy was 81%. The ypN0 patients were identified with 91% sensitivity and 38% specificity using ultrasound and intraoperative assessment of both sentinel and tattooed lymph node according to the final histology. Discussion/Conclusion Lymph node marking with carbon dye is a useful and..
Hop Phytochemicals and Their Potential Role in Metabolic Syndrome Prevention and Therapy
Historically, hop cones (Humulus lupulus) have been used since ancient times as a remedy for many ailments and, as a source of polyphenols and bitter acids, is very effective in the treatment of metabolic syndrome (MS). Hop flavonoids, particularly xanthohumol (XN), are substances with hypoglycemic, antihyperlipidemic, and antiobesity activities. Iso-α-acids (IAA) and matured hop bitter acids (MHBA) improve health by influencing lipid metabolism, glucose tolerance, and body weight. The modulatory effect of IAA and MHBA on lipid metabolism may also be responsible for a loss in body weight. These results suggest promising applications for IAA, MHBA, and XN in humans, particularly in the prevention of diet-induced obesity and diabetes