20 research outputs found

    Evaluating the Factor Structure and Construct Validity of the Intensions Health-Related Masculine Values Scale: Is It Really a Measure of Health-Related Masculine Values?

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    The Intensions Health-Related Masculine Values Scale (IHRMVS) was recently developed to address the growing interest in examining the associations between strengths-based masculinity and men’s health. However, while the original development and validation work was promising, replication and extension of several aspects of the scale’s validity should be undertaken before the scale can be adopted for widespread use. Using a large sample of British men, aged 18-80 years, exploratory factor analyses revealed a single factor for both the original age grouping (18-29 years, n = 166) and an older group of men (≥ 30 years, n = 404), failing to replicate the two-factor structure proposed in the parent study. Additionally, correlations between scores on the IHRMVS and scores on a measure of traditional male role norms were mostly non-significant or very small. Similar findings emerged in our analyses of the associations between scores on the IHRMVS and indices of depression, anxiety, help-seeking attitudes, sleep disturbance, and smoking. These findings draw into question the utility of the IHRMVS as a measure of positive, health-related masculine values

    Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

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    IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

    Media Images of Objectified Women Can Have a Harmful Effect on Men

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    Even mild images of objectified women can make men feel hostile and anxious.York's Knowledge Mobilization Unit provides services and funding for faculty, graduate students, and community organizations seeking to maximize the impact of academic research and expertise on public policy, social programming, and professional practice. It is supported by SSHRC and CIHR grants, and by the Office of the Vice-President Research & Innovation. [email protected] www.researchimpact.c

    Fear of Pain and Fear of Falling among Younger and Older Adults with Musculoskeletal Pain Conditions

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    BACKGROUND: The fear-avoidance model of pain accounts for the debilitating consequences of strong fear as a component of reactions to painful conditions (eg, movements become anxiety-provoking because they cause pain). The model, which is supported in the literature, posits that fear of pain interferes with recovery because it leads to avoidance of beneficial activity. Despite the high prevalence of pain among the elderly, investigations of fear of pain in this population are scarce. A related construct, fear of falling, has been studied among elderly (but not younger) adults as an age-specific concern

    Evaluation of success in competitive figure skating : an analysis of interjudge reliability

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    Evaluation du niveau d'entente ou de fiabilité entre juges d'élite affectés aux compétitions de patinage artistique internationales. Variations selon la discipline (couples, femmes, hommes), selon le pointage (technique ou artistique), le programme (court ou long)

    Higher-order model of resilience in the Canadian forces.

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