Impact of hypoglycemia on patients with type 2 diabetes mellitus and their quality of life, work productivity, and medication adherence.

BackgroundThe purpose of this study was to determine the characteristics of adults with type 2 diabetes mellitus (T2DM) that correlate with greater risk of hypoglycemia and determine the impact of hypoglycemia on health-related quality of life, work productivity, and medication adherence from a patient perspective.MethodsData from a large web-based survey were retrospectively analyzed. Adults with a diagnosis of T2DM taking antihyperglycemic agents were included in the analysis. Participants with knowledge of their hypoglycemic history were divided into three groups: those experiencing recent hypoglycemia (previous 3 months), those experiencing nonrecent hypoglycemia, and those never experiencing hypoglycemia.ResultsOf the participants with T2DM taking antihyperglycemic agents who were knowledgeable of their hypoglycemia history, 55.7% had ever experienced hypoglycemia. Of those, 52.7% had recent hypoglycemia. Compared with those who never experienced hypoglycemia, those who experienced hypoglycemia tended to: be younger; be more aware of their glycated hemoglobin (HbA1c) levels; have higher HbA1c levels; have a higher body mass index; have higher Charlson Comorbidity Index scores; be on insulin, sulfonylureas, and/or glucagon-like peptide-1 agonists; and be less adherent to their antihyperglycemic agents. Hypoglycemia interfered with social activities, caused more missed work (absenteeism), more impairment while at work (presenteeism), and decreased overall work productivity compared with patients who had never experienced hypoglycemia. Overall health-related quality of life, as determined by the Short Form-36 health questionnaire, was negatively impacted by hypoglycemia. Both Physical and Mental Summary scores were significantly lower for the recent hypoglycemia and nonrecent hypoglycemia groups compared with the never hypoglycemia group.ConclusionHypoglycemia can negatively impact many aspects of life. Greater awareness of those who are at risk for developing hypoglycemia can lead to the development of measures (eg, patient and physician education) to prevent future hypoglycemia episodes

Revision of the genus Philonome Chambers and its proposed reassignment to the family Tineidae (Lepidoptera, Tineoidea)

International audienceThe New World genus Philonome Chambers, 1874 is revised. This genus comprises twelve species, seven of which are described as new: two species, P. nigrescens sp. n. and P. wielgusi sp. n., from the United States; four species, P. albivittata sp. n., P. curvilineata sp. n., P. kawakitai sp. n., and P. lambdagrapha sp. n., from French Guiana; and one species, P. penerivifera sp. n., from Brazil. Lectotypes are designated for Philonome clemensella Chambers, 1874 and P. rivifera Meyrick, 1915. Partially on evidence of their head morphology and particularly from molecular evidence, the genus Philonome, previously associated with Bucculatricidae or Lyonetiidae, is reassigned to Tineidae. A possible systematic position of Philonome within Tineidae is discussed. Eurynome Chambers, 1875, is synonymized with Argyresthia Hübner, 1825 (Argyresthiidae). Photographs of adults and illustrations of genitalia, when available, are provided for all described species of Philo-nome and two species previously misplaced in Philonome, Argyresthia luteella (Chambers, 1875) and Elachista albella (Chambers, 1877). In addition, DNA barcodes were used for the delimitation of most species

Report on OTHER proposals for SSPEX

The only unifying factor among the experiments discussed is that they are all unique Opportunities and/or Techniques for High-caliber Experimental Research (OTHER). Thirteen of the experiments are briefly described

Analisis de las estrategias comerciales del “Auto Lavado Almendarez” ubicado en el municipio de Managua correspondiente al periodo 2019

En la presente tesis se describirá las generalidades de los servicios que ofrece Auto Lavado Almendarez por lo que se elaborara un análisis cualitativo a través de matriz FODA y modelo de competitividad establecido por Michael Porter en la empresa Auto Lavado Almendarez así también se evaluara las unidades de negocio de la empresa Auto Lavado Almendarez por medio de la matriz BCG para proponer a través del análisis de estudio; estrategias comerciales para mejorar el marketing de auto lavado Almendarez. El método utilizado para llevar a cabo el trabajo de tipo descriptivo, aplicado a la empresa Auto Lavado Almendarez es no experimental de índole transversal, donde se entrevistará al gerente general y personal del área de marketing para obtener la información de la entidad, con el fin de verificar el problema de la empresa y posibles soluciones para mejores tomas de decisiones en el área de marketing es de tipo cualitativa y cuantitativa, se realiza un análisis FODA, la herramienta de las cinco fuerzas de Porter , matriz BCG a la empresa auto lavado Almendarez. Como conclusión las estrategias de Marketing son herramientas que ayudan a las empresas a dominar mejor el mercado donde se encuentran, las empresas por lo general buscan lo que es maximizar sus utilidades, entonces, es cuando ponen en práctica todos sus conocimientos de ventas para ofrecer los productos o servicios y que tengan un éxito dentro del mercado donde se encuentra la empresa, por lo tanto se propone a través del análisis de estudio; estrategias comerciales para mejorar el marketing de auto lavado Almendarez. Palabras Claves: Estrategias comerciales, Marketing, FODA, Cinco Fuerzas de Porter, BC

Ranges and Movements of Montezuma Quail in Southeast Arizona

Historical assumptions about Montezuma quail movements and home ranges at the population level are limited due to the lack of markrecapture studies on this species from which solid conclusions can be derived. Such information is crucial for estimating population sizes, densities, and rate of emigration and immigration throughout the landscape. Our study examined home range size of 29 Montezuma quail and movements of 65 quail in southeast Arizona from 2008–2010. We used radio telemetry to follow radio-tagged birds in 3 study sites that varied in vegetation composition and topography. Mean home range size (MCP) was about was similar (51 ha) to the largest use area (50 ha) described in the literature for this species. The largest MCP home range estimate (206.7 ha) was far larger than what has been reported in the literature. Within a season, the largest mean maximum distance moved between 2 locations was 1,128.4 ± 619.5 m and the largest maximum linear distance between 2 locations for an individual was 2,375.5 m. Results from our research should help to address knowledge gaps about Montezuma quail home ranges and movements and provide a baseline to assist management of this species in the future

Survival Demographics of Montezuma Quail in Southeast Arizona

Many facets of Montezuma quail (Cyrtonyx montezumae mearnsi) population dynamics, such as survival and causes of mortality, are unknown because of limited or lack of mark–recapture studies on wild populations of this species. Much of what is known about this species comes from casual observations in the field or from dog-assisted flush-count surveys. Further insight into rate and causes of mortality for this species is necessary to ensure proper conservation measures. We evaluated survival and causes of mortality of Montezuma quail in southeastern Arizona from winter 2007 to spring 2010. Survival was determined from quail captured, radiotagged, and monitored among 3 separate study sites. In 2 of these sites hunting was permitted; and in 1 site (the control) hunting was not permitted. Estimation of accurate mortality rates in hunted sites was complicated by large quantities of censored data, some of which was attributable to lack of reported mortalities from hunting. Mortality in the control site may have been compounded by a combination of stochastic events (i.e., wildfire, freezing) occurring during the study. Mortality rate for all sites were higher than any estimates reported or hypothesized in known scientific literature. The estimated rate of survival, combined among the 3 sites, was 21.9% from autumn 2008 to autumn 2009