Contextual novelty changes reward representations in the striatum

Reward representation in ventral striatum is boosted by perceptual novelty, although the mechanism of this effect remains elusive. Animal studies indicate a functional loop (Lisman and Grace, 2005) that includes hippocampus, ventral striatum, and midbrain as being important in regulating salience attribution within the context of novel stimuli. According to this model, reward responses in ventral striatum or midbrain should be enhanced in the context of novelty even if reward and novelty constitute unrelated, independent events. Using fMRI, we show that trials with reward-predictive cues and subsequent outcomes elicit higher responses in the striatum if preceded by an unrelated novel picture, indicating that reward representation is enhanced in the context of novelty. Notably, this effect was observed solely when reward occurrence, and hence reward-related salience, was low. These findings support a view that contextual novelty enhances neural responses underlying reward representation in the striatum and concur with the effects of novelty processing as predicted by the model of Lisman and Grace (2005)

Character Formulae and Partition Functions in Higher Dimensional Conformal Field Theory

A discussion of character formulae for positive energy unitary irreducible representations of the the conformal group is given, employing Verma modules and Weyl group reflections. Product formulae for various conformal group representations are found. These include generalisations of those found by Flato and Fronsdal for SO(3,2). In even dimensions the products for free representations split into two types depending on whether the dimension is divisible by four or not.Comment: 43 pages, uses harvmac,version 2 2 references added, minor typos correcte

The Information Geometry of the Ising Model on Planar Random Graphs

It has been suggested that an information geometric view of statistical mechanics in which a metric is introduced onto the space of parameters provides an interesting alternative characterisation of the phase structure, particularly in the case where there are two such parameters -- such as the Ising model with inverse temperature $\beta$ and external field $h$. In various two parameter calculable models the scalar curvature ${\cal R}$ of the information metric has been found to diverge at the phase transition point $\beta_c$ and a plausible scaling relation postulated: ${\cal R} \sim |\beta- \beta_c|^{\alpha - 2}$. For spin models the necessity of calculating in non-zero field has limited analytic consideration to 1D, mean-field and Bethe lattice Ising models. In this letter we use the solution in field of the Ising model on an ensemble of planar random graphs (where $\alpha=-1, \beta=1/2, \gamma=2$) to evaluate the scaling behaviour of the scalar curvature, and find ${\cal R} \sim | \beta- \beta_c |^{-2}$. The apparent discrepancy is traced back to the effect of a negative $\alpha$.Comment: Version accepted for publication in PRE, revtex

Comparison of the EMG Activities in the Vastus Medialis Oblique and Vastus Lateralis Muscles During Hip Adduction and Terminal Knee Extension Exercise Protocols

The purpose of this study was to compare the electromyographic (EMG) activities in the vastus medialis oblique (VMO) and vastus lateralis (VL) muscles during two open chain exercises commonly used in the management of patellofemoral pain syndrome (PFPS). Twenty-five (14 female and 11 male) healthy subjects participated in the study. The A 2 (testing condition) x 2 (exercise type) x 2 (gender) quasi-experimental design was employed. Using surface electrodes, the EMG activities in the VMO and the VL muscles during ten repetitions of hip adduction and terminal knee extension exercises were recorded. The order of presentation of the experimental conditions was randomized. The three-way repeated ANOVA revealed no significant main effects for testing conditions, exercise type or gender, but the terminal knee extension exercise type x gender interaction effect was statistically significant (F= 8.28,

The Space Debris Sensor Experiment

The Space Debris Sensor (SDS) is a NASA Class 1E technology demonstration external payload aboard the International Space Station (ISS). With approximately one square meter of detection area, the SDS is attached to the European Space Agency Columbus module facing the ISS velocity vector with minimal obstruction from ISS hardware. The SDS is the first flight demonstration of the Debris Resistive/Acoustic Grid Orbital NASA-Navy Sensor (DRAGONS) technology developed and matured over 10 years by the NASA Orbital Debris Program Office (ODPO), in concert with the DRAGONS consortium, to provide information on the sub-millimeter scale orbital debris environment. The SDS demonstrated the capacity to read 4 resistive grids at 1 Hz, 40 acoustic sensors at 500 kHz, and record and downlink impact data to the ground. Observable and derived data from the SDS could provide information to models that are critical to understanding risks the small debris environment poses to spacecraft in low Earth orbit. The technology demonstrated by the SDS is a major step forward in monitoring and characterizing the space debris environment. This paper will address the technical performance of the SDS during its operational lifetime and its realization of technical and scientific goals. The SDS was intended to operate for 3 years; however, the payload incurred multiple anomalies during its operational life. Subsequently termed Anomaly #1, the first was the symptomatic loss of low data rate 1553 channel command and telemetry. The second, Anomaly #2, was loss of all low- and medium-data rate (Ethernet) telemetry. Anomaly #2 proved to be unrecoverable, leading to loss of the payload after approximately 26 days on-board the ISS. Therefore, this paper also addresses the anomalies that occurred during operation of the SDS, their attribution, and their resolution. Lessons learned are described when relevant to anomaly identification, attribution, and resolution

New methods in conformal partial wave analysis

We report on progress concerning the partial wave analysis of higher correlation functions in conformal quantum field theory.Comment: 16 page

HIV education in a Siberian prison colony for drug dependent males

AIM: To evaluate the effectiveness of an HIV peer training program conducted in a colony for drug dependent male prisoners in Siberia, Russia. METHOD: Questionnaires were used to collect data pre and post peer training sessions. Three peer training sessions were conducted between questionnaires. Fifteen to twenty inmates were trained as peer educators at each week-long health education training session. RESULTS: In 2000 and 2001, 153 and 124 inmates completed the questionnaire respectively. Respondents in both years reported similar health and injecting histories and comparable levels of sexual activity. Respondents in 2001 were significantly more likely to correctly identify both how HIV can and cannot be transmitted compared to respondents in 2000. The prevalence of tattooing in prison decreased significantly between questionnaires. However, there was virtually no reported use of bleach to clean tattooing or injecting equipment in either 2000 or 2001. Access to condoms increased significantly between questionnaires. CONCLUSIONS: While this training program was associated with improved HIV knowledge, the Ministry of Justice should consider improved and additional harm reduction strategies. These include increased availability of bleach and condoms and the introduction of methadone treatment and syringe exchange in prison

Implications of Improved Higgs Mass Calculations for Supersymmetric Models

We discuss the allowed parameter spaces of supersymmetric scenarios in light of improved Higgs mass predictions provided by FeynHiggs 2.10.0. The Higgs mass predictions combine Feynman-diagrammatic results with a resummation of leading and subleading logarithmic corrections from the stop/top sector, which yield a significant improvement in the region of large stop masses. Scans in the pMSSM parameter space show that, for given values of the soft supersymmetry-breaking parameters, the new logarithmic contributions beyond the two-loop order implemented in FeynHiggs tend to give larger values of the light CP-even Higgs mass, M_h, in the region of large stop masses than previous predictions that were based on a fixed-order Feynman-diagrammatic result, though the differences are generally consistent with the previous estimates of theoretical uncertainties. We re-analyze the parameter spaces of the CMSSM, NUHM1 and NUHM2, taking into account also the constraints from CMS and LHCb measurements of B_s to \mu+\mu- and ATLAS searches for MET events using 20/fb of LHC data at 8 TeV. Within the CMSSM, the Higgs mass constraint disfavours tan beta lesssim 10, though not in the NUHM1 or NUHM2.Comment: 22 pages, 17 figure

X-ray observations of AM Herculis from OSO-8

The white dwarf binary system AM Herculis (2A1815+500) was observed in X-rays at both low energies (E less 10 keV) and higher energies. The exact shape of the spectrum, particularly at the higher energies, has yet to be determined. Results from the high energy scintillation spectrometer on OSO-8 are presented. These are combined with results published elsewhere obtained concurrently with the proportional counter on the same satellite, thereby giving for the first time coincident observations of AM Her over the range 2 to 250 keV

The Quasinormal Mode Spectrum of a Kerr Black Hole in the Eikonal Limit

It is well established that the response of a black hole to a generic perturbation is characterized by a spectrum of damped resonances, called quasinormal modes; and that, in the limit of large angular momentum ($l \gg 1$), the quasinormal mode frequency spectrum is related to the properties of unstable null orbits. In this paper we develop an expansion method to explore the link. We obtain new closed-form approximations for the lightly-damped part of the spectrum in the large-$l$ regime. We confirm that, at leading order in $l$, the resonance frequency is linked to the orbital frequency, and the resonance damping to the Lyapunov exponent, of the relevant null orbit. We go somewhat further than previous studies to establish (i) a spin-dependent correction to the frequency at order $1 / l$ for equatorial ($m = \pm l$) modes, and (ii) a new result for polar modes ($m = 0$). We validate the approach by testing the closed-form approximations against frequencies obtained numerically with Leaver's method.Comment: 18 pages, 3 tables, 3 figure