Biologically active compounds and antioxidant capacity of cichorium intybus l. Leaves from Montenegro

The aim of this study was to determine biologically active substances (BAS) in the samples of Cichorium intybus L. leaves from different sources (wild and cultivated) in Montenegro and to investigate the potential influence of location and origin on the BAS. Fiber and fatty acid composition, amount of pigments, total phenols and flavonoids and some phenolic acids were analyzed. Antioxidant activity was also determined by three methods (DPPH, FRAP and ABTS) and the results obtained from all tests were used to calculate the antioxidant potency composite index (ACI). The dietary fiber profile confirmed chicory leaves as an important source of fiber. The majority of fats in chicory leaves consist-of unsaturated fatty acids, while saturated fatty acids were represented mainly by palmitic acid. Chlorophyll a and b, lutein and beta-carotene were the main pigments in chicory leaves. ACI index had a good correlation with the total phenolic and total flavonoid content. All these features reinforced the interest of including chicory in modern diet as a healthy alternative to the variety of commonly used vegetables

Volunteer Support in the Lives of People with Disability

Volunteer Support in the Lives of People with Disabilit

Protective role of vitamins E and C in carbon tetrachloride induced acute liver damage

The CCL4 hepatotoxic impact is achieved when it is activated to from highly reactive radicals, which have various effects; initiation of lipid peroxidation being probably the most important one. The toxic outcome may be prevented through use of antioxidants; vitamin E presenting the first line of defence. Keeping the concentration of reduced vitamin E,requires a network of other antioxidants that can reduce the radical from of vitamin E to its native from. Vitamin C is an antioxidant that is able to reduce vitamin E directly

Cytotoxic and Antimicrobial Activities of Cantharellus cibarius Fr. (Cantarellaceae)

Antibacterial and cytotoxic activities of cyclohexane, dichloromethane, methanol, and aqueous extracts of Cantharellus cibarius were tested. Broth microdilution assay was performed against 10 bacterial strains (Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Bacillus subtilis, Enterococcus feacalis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella abony), with emphasis on Helicobacter pylori. Methanol extract was the most active against H. pylori strains with minimal inhibitory concentration values between 4 and 32 mu g/mL. All extracts were active against antibiotic resistant H. pylori. Methanol and aqueous extracts had no cytotoxicity against tested cell lines, whereas cyclohexane and dichloromethane extracts were active against HeLa and N87 cells, but also against healthy MRC-5 cells (IC50 39.26 +/- 1.24-134.79 +/- 0.01 mu g/mL). The tested aqueous extracts have shown 68% of angiotensin-converting enzyme inhibitory activity in doses of 1.25 mg/mL. Chemical analysis has shown the presence of linoleic, cis-vaccenic, and oleic acids, sterols, beta-glucans, and polyphenolic compounds

The Scope-University of Melbourne Partnership Submission to the Senate Select Committee on Autism

This submission is a collaboration between one of Australia’s leading disability service providers and leading academics from the University of Melbourne on key issues relating to the services, support and life outcomes experienced by Autistic people in Australia and the associated need for a National Autism Strategy. The submission is grounded in research evidence and contains both policy and practice recommendations. Importantly, several of the contributors to this submission identify as Autistic, and in addition to their academic and professional experience bring to the submission the expertise of their lived experience. The Scope-University of Melbourne Partnership submission to this inquiry will focus on key issues relating to the services, support and life outcomes experienced by Autistic people in Australia, specifically focusing on the areas of advocacy, education, employment, health and mental health and the NDIS