The CCL4 hepatotoxic impact is achieved when it is activated to from highly reactive radicals, which have various effects; initiation of lipid peroxidation being probably the most important one. The toxic outcome may be prevented through use of antioxidants; vitamin E presenting the first line of defence. Keeping the concentration of reduced vitamin E,requires a network of other antioxidants that can reduce the radical from of vitamin E to its native from. Vitamin C is an antioxidant that is able to reduce vitamin E directly