External morphology of eyes and Nebenaugen of caridean decapods–ecological and systematic considerations

Most caridean decapods have compound eyes of the reflecting superposition kind, and additionally some possess an accessory eye-like organ of unknown function, also referred to as the nebenauge.We examined 308 caridean genera to assess the general morphology of the eye, rostrum length, eye diameter and the presence or absence and, when present, the diameter of the nebenauge.We have attempted to relate these data to ecological and taxonomic considerations.We consider there to be 6 distinct eye types based on the margin between the eyestalk and cornea. The presence of nebenaugen appears to be generally linked to an active lifestyle, as evidenced by the fact that species that have nebenaugen tend to have larger eyes and are more likely to have a distinct rostrum.We suggest that the inconsistencies in its presence/absence under both systematic and ecological lenses may indicate that when present it has various roles relating to behavioural and physiological rhythms

Linking eye design with host symbiont relationships in pontoniine shrimps (crustacea, decapoda, palaemonidae)

Symbiosis is prevalent in the marine environment with many studies examining the effects of such interactions between host and symbiont. Pontoniine shrimps are a group whose ecology is characterised by symbiotic interactions. This investigation examines the gross morphology of Pontoniinae compound eyes and superficial optical parameters with reference to their symbiotic relationship or lifestyle category; free-living, ectosymbiont, endosymbiont (bivalves) or endosymbiont (non-bivalves). The eye morphologies of free-living and ectosymbiotic species are very similar, yet differ from both forms of endosymbiotic species. Endosymbionts have significantly smaller and simpler eyes with larger facets and bigger interommatidial angles and eye parameters for increased sensitivity levels. However bivalve endosymbionts form an intermediary group between non-bivalve endosymbionts and ectosymbionts as a result of their more active lifestyle. The accessory eye or "nebenauge", although of uncertain function, commonly occurs in free-living Pontoniinae species but rarely in endosymbionts apart from in more primitive species. The variation in morphology reflects tensions between functional requirements and ecological pressures that have strongly influenced eye design in Pontoniinae. © 2014 Dobson et al

Rural entrepreneurial space and identity: A study of local tour operators and ‘the Nenets’ indigenous reindeer herders

The tourism industry is a capitalist activity concerned with the production, accumulation and distribution of wealth. Power is an important arena for research in this respect as diverse outcomes for the local economy in general, and its players specifically, provide important aspects to study when considering the lives of rural entrepreneurs. However, it may be argued that whilst Marxist theorists using critical approaches on power have tended to focus on issues around the equality of power relations between actors or stakeholders, the inherently spatial nature of power has received less emphasis. This paper focuses on an exploration of the spatiality of power which surrounds entrepreneurship and tourism industry development. The conceptual framework, based on the application of Lefebvre’s (1991) concepts supplemented by Gaventa’s (2004) power cube, is placed within the broader context of Marx Political Economy and Historical Materialism. The main value of Lefebvre’s (1991) work for the current research is seen in his notion of space as an ‘ensemble’ formed from i) representational space (or our conception of it); ii) spatial practices, which are our interaction with physical and material aspects of space; and, iii) the spaces of representation, or our lived space. They are intertwined dimensions and therefore intradependent (Theobald 1997). These three types of dialectically inter-related spaces are merged into a single ensemble which forms our experience of social space. Gaventa (2006) extends this further with the introduction of power through space and explores the visible, hidden, and invisible forms of power which are negotiated at different spatial scales and which are experienced as closed, invited, or (re)claimed. The case study geographic area examined is in transition from Socialism to Capitalism with the tourism industry at early stages of its development. For this, reason entrepreneurial activity and power struggles over the key business asset, the landscape, are currently being played out. Literature theorising rural entrepreneurship (Marlow et al 2014) and especially the notion of skills and training for diversifying rural enterprise (Vik and McElwee 2011; Pyysiäinen et al 2006) is an important context here. This is particularly born out in the relationships between the indigenous reindeer herders, ‘the Nenets’, local tour operators, and the local government of Yamal in the Yamal-Nenets Autonomous Okrug (YNAO) of the Russian Federation which provides the core material. The research has been conducted through an ethnographic field study with indigenous reindeer herder communities as well as interviews with local stakeholders. This allows for insights into the spatiality of power surrounding rural entrepreneurial space and tourism enterprise to be gained

Insights into the morphology of symbiotic shrimp eyes (Crustacea, Decapoda, Palaemonidae); the effects of habitat demands

Morphometric differences in the optical morphology of symbiotic palaemonid shrimps can be observed among species symbiotic with different host organisms. Discriminant functional analysis revealed three distinct groups within the species examined. Of these, bivalve symbionts appear to have an eye design that is solely unique to this host-symbiont grouping, a design that spans across multiple genera of phylogenetically unrelated animals. Although some taxonomic effects may be evident, this does not explain the difference and similarities in eye morphology that are seen within these shrimps. Therefore evolutionary pressures from their host environments are having an impact on the optical morphology of their eyes however, as indicated by host-hopping events there ecological adaptations occur post host invasion

Food activities and identity maintenance in old age: a systematic review and meta-synthesis

This article has been made available through the Brunel Open Access Publishing Fund.Objectives: Services provided to older people should be developed based on active ageing policies. Nutrition is one aspect of active ageing, but little is known about how food activities contribute to psychological well-being in later life. This is a systematic review of qualitative and quantitative research that answers the question ‘What is known about the relationship between food activities and the maintenance of identities in old age?’

Endometriosis and the Fallopian Tubes: Theories of Origin and Clinical Implications

Endometriosis is a common, oestrogen driven chronic condition, where endometrium-like epithelial and stromal cells exist in ectopic sites. At present, no curative treatments are available and the existing evidence for disease progression is conflicting. The pathogenesis is still unknown and evidently complex, as mechanisms of initiation may depend on the anatomical distribution of endometriotic lesions. However, amongst the numerous theories and plethora of mechanisms, contributions of the fallopian tubes (FT) to endometriosis are rarely discussed. The FT are implicated in all endometriosis associated symptomatology and clinical consequences; they may contribute to the origin of endometriotic tissue, determine the sites for ectopic lesion establishment and act as conduits for the spread of proinflammatory media. Here, we examine the available evidence for the contribution of the human FT to the origin, pathogenesis and symptoms/clinical consequences of endometriosis. We also examine the broader topic linking endometriosis and the FT epithelium to the genesis of ovarian epithelial cancers. Further studies elucidating the distinct functional and phenotypical characteristics of FT mucosa may allow the development of novel treatment strategies for endometriosis that are potentially curative

Working out what works: The role of tacit knowledge where urban greenspace research, policy and practice intersect

Policymakers and practitioners working in urban greenspace management want to know what kind of interventions are effective in promoting mental wellbeing. In practice, however, they rely on multiple forms of knowledge, often in unwritten form. This paper considers how such knowledge is interpreted and used by a range of stakeholders to identify greenspace interventions to support residents' health and wellbeing in one UK city. It examines the interface between academic research, policy and practice, drawing on the findings of a three-year study in Sheffield, UK. The Improving Wellbeing through the Urban Nature project investigated the links between 'urban nature' and mental health. One strand of the research sought to influence policy and practice, and this article presents findings and reflects on some of the processes of this exercise. It highlights the role of tacit knowledge in practice and its influence on practitioners' choice of greenspace interventions and the challenges in drawing on such knowledge to influence policy. The findings affirm practice-based knowledge as socially situated, interpretively fashioned and politically weighted. This paper concludes by demonstrating the importance of considering the local context when devising policy prescriptions for greenspace provision and management

Genetic Risk as a Marker of Amyloid-β and Tau Burden in Cerebrospinal Fluid.

BACKGROUND: The search for a biomarker of Alzheimer's disease (AD) pathology (amyloid-β (Aβ) and tau) is ongoing, with the best markers currently being measurements of Aβ and tau in cerebrospinal fluid (CSF) and via positron emission tomography (PET) scanning. These methods are relatively invasive, costly, and often have high screening failure rates. Consequently, research is aiming to elucidate blood biomarkers of Aβ and tau. OBJECTIVE: This study aims to investigate a case/control polygenic risk score (PGRS) as a marker of tau and investigate blood markers of a combined Aβ and tau outcome for the first time. A sub-study also considers plasma tau as markers of Aβ and tau pathology in CSF. METHODS: We used data from the EDAR*, DESCRIPA**, and Alzheimer's Disease Neuroimaging Initiative (ADNI) cohorts in a logistic regression analysis to investigate blood markers of Aβ and tau in CSF. In particular, we investigated the extent to which a case/control PGRS is predictive of CSF tau, CSF amyloid, and a combined amyloid and tau outcome. The predictive ability of models was compared to that of age, gender, and APOE genotype ('basic model'). RESULTS: In EDAR and DESCRIPA test data, inclusion of a case/control PGRS was no more predictive of Aβ, and a combined Aβ and tau endpoint than the basic models (accuracies of 66.0%, and 73.3% respectively). The tau model saw a small increase in accuracy compared to basic models (59.6%). ADNI 2 test data also showed a slight increase in accuracy for the Aβ model when compared to the basic models (61.4%). CONCLUSION: We see some evidence that a case/control PGRS is marginally more predictive of Aβ and tau pathology than the basic models. The search for predictive factors of Aβ and tau pathologies, above and beyond demographic information, is still ongoing. Better understanding of AD risk alleles, development of more sensitive assays, and studies of larger sample size are three avenues that may provide such factors. However, the clinical utility of possible predictors of brain Aβ and tau pathologies must also be investigated.*'Beta amyloid oligomers in the early diagnosis of AD and as marker for treatment response'**'Development of screening guidelines and criteria for pre-dementia Alzheimer's disease'.Multiple funders listed on paper