Photodiode based on epitaxial silicon with high sensitivity at the wavelength 254 nm

A mathematical model of the construction of silicon photodiode based on epitaxial structure enabling to regulate the absorption edge of silicon in the long-wave spectral range is presented. The suggested model allows calculating the construction that possesses low sensitivity for the wavelengths larger than 600 nm and maximal values near the wavelength 254 nm

Pedagogical tact of high-scool teacher, directions for action

У статті представлений аналіз методичних підходів, запропонованих кафедрою нейрохірургії і неврології Одеського національного медичного університету, щодо підвищення якості підготовки викладачів. Головним у педагогічному такті є ставлення викладача до своєї педагогічної діяльності, до особистості студента й до самого себе, вміння дотримуватися міри в застосуванні засобів виховного впливу та ефективно впливати на психіку студентів, з метою кращого опитування навчальної програми.The article presents the analysis of methodological approaches proposed by the Department of Neurosurgery and Neurology of Odesa National Medical University, to improve the quality of academic and clinical work. Primarily in the pedagogical tact is the ratio of teacher to his academic work, the individual student and to himself. Ability to follow in applying measures of educational influence and effectively influence the mentality of students in order to enhance the curriculum

Simulated patient: a textbook

The textbook covers the basic principles of organizing the educational process involving standardized patients. For heads of secondary and higher medical educational institutions, teaching staff, and working groups on the implementation of the “Simulated patient” method

Some aspects of consulting work conducting at the department of neurosurgery and neurology of Odessa state medical university

У статті представлений аналіз методичних підходів проведення консультативної роботи співробітниками кафедри нейрохірургії і неврології Одеського державного медичного університету та рекомендації щодо підвищення її якості.The article presents an analysis of methodological approaches of consultative work by the department of neurosurgery and neurology of Odessa State Medical University and recommendations to improve its qualit

Ways to increase motivation of students for improving the quality of education at the department of neurosurgery and neurology of Odesa national medical university

У статті представлений аналіз методичних підходів щодо підвищення мотивації студентів для покращення якості навчання на кафедрі нейрохірургії і неврології Одеського національного медичного університетуThe article presents an analysis of methodological approaches to improve students’ motivation to improve the quality of teaching at the Department of Neurosurgery and Neurology of Odesa National Medical University

The effectiveness of the original amantadine sulfate in the complex treatment of patients with ischemic stroke in the acute period

Цель – определить эффективность оригинального амантадина сульфата инфузии (ПК-МЕРЦ®, Мерц Фарма ГмбХ и Ко. КГаА) в суточной дозе 200 мг внутривенно в течение 5 дней терапии в комплексном лечении пациентов в остром периоде ишемического инсульта. Материалы и методы. Обследовано 63 пациента в остром периоде ишемического инсульта. Все пациенты основной и контрольной групп получали стандартное лечение в соответствии с клиническим протоколом, приказ МЗ Украины от 03.08.2012, № 602. Пациентам основной группы (n=31) на фоне базисного лечения дополнительно был назначен амантадина сульфат (ПК-МЕРЦ®, Мерц Фарма ГмбХ и Ко. КГаА) внутривенно капельно в суточной дозе 200 мг в течение 5 дней. Пациентам контрольной группы (n=30) амантадина сульфат не назначался. Оценку по шкалам ком Глазго, NIHSS выполняли в 1-е, 3-и, 5-е сутки заболевания. Результаты. Одновременное со стандартным лечением внутривенное введение амантадина сульфата (ПК-МЕРЦ®, Мерц Фарма ГмбХ и Ко. КГаА) положительно влияет на регресс очаговой неврологической симптоматики по шкалам NIHSS у пациентов в остром периоде ишемического инсульта, позволяет увеличить долю пациентов в сознании или легкой степени его нарушения по шкале Глазго, т.е. вызывать более раннее «пробуждение» в остром периоде ишемического инсульта. Выводы. Эффективность амантадина сульфата при ишемическом инсульте, вероятно, связана с его политропным действием, направленным не только на улучшение уровня сознания (коррекция нейромедиаторной недостаточности), но и нейропротективное действие.Objective – to determine the effectiveness of the original amantadine sulfate infusion (PK-MERZ®, Merz Pharma GmbH & Co. KGaA) at a daily dose of 200 mg intravenously for 5 days of therapy in treatment of patients with acute ischemic stroke. Materials and methods. The study involved 63 patients with acute ischemic stroke. All patients and control group, received standard treatment in accordance with the clinical protocol order Ministry of Health of Ukraine from 03.08.2012, the number 602. Patients of the main group (n=33) on the back of the base treatment was additionally appointed as amantadine sulfate (PK-MERZ®, Merz Pharma GmbH & Co. KGaA) intravenously in a daily dose of 200 mg for 5 days. Patients in the control group (n=30) – amantadine sulfate was not prescribed. Assessment by GCS, NIHSS was performed in the 1-st, 3-rd, 5-th day of the disease. Results. Simultaneous with the standard treatment of intravenous administration of amantadine sulfate (PK-MERZ®, Merz Pharma GmbH & Co. KGaA) has a positive effect on the regression of focal neurological symptoms by NIHSS score in patients with acute ischemic stroke, increases the proportion of patients in the minds of his or mild violation of Glasgow scale, i.e, cause earlier "awakening" in acute ischemic stroke. Conclusions. The effectiveness of amantadine sulfate in ischemic stroke is probably related to its polytrophic action aimed not only at improving the level of consciousness (correction of neurotransmitter deficiency), and neuroprotective effects

FACTORS ASSOCIATED WITH D-DIMER ELEVATION IN PATIENTS WITH VENOUS THROMBOEMBOLIC EVENTS

Aim. To study the factors associated with elevated D-dimer levels in patients with acute venous thromboembolic events (VTEE). material and methods. The study included 111 patients (76 men and 35 women aged 18–76 years) with a first or repeat episode of deep vein thrombosis (DVT) and/or pulmonary embolism (PE) in the last 2 months. The majority of the patients (n=80) received unfractionated heparin (UFH) for at least 5 days, followed by warfarin (international normalized ratio (INR) control at least once a month; target INR 2,0–3,0). Some patients (n=31) received therapeutic doses of enoxaparin (1 mg/kg subcutaneously, every 12 hours) for at least 30 days, followed by warfarin treatment. D-dimer levels (norm <0,5 mkg/ml) were measured by the latex agglutination method, with the use of “STA LIATEST >® D-DI” reagents (Diagnostica Stago). Results. D-dimer levels varied from 0,02 to 9,96 mkg/ml (median 1,05 mkg/ml, interquartile range 0,49–1,99 mkg/ml) and exceeded the upper norm limit in 74% of the patients. There was a positive association between D-dimer levels and thrombus “size” (r=0,304; p<0,001), and a negative association between D-dimer levels and >< 0,001), and a negative association between D-dimer levels and thrombus “age” (r=-0,418; p<0,001). Predictors of D-dimer elevation were identified among 150 demographic, anthropometric, anamnestic, clinical, laboratory, genetic, or ultrasound parameters and VTEE risk factors. The results of the multivariate stepwise regression analysis demonstrated that female gender, chronic heart failure (CHF), VTEE symptom duration ><28 days, and thrombus “size” >< 0,001). Predictors of D-dimer elevation were identified among 150 demographic, anthropometric, anamnestic, clinical, laboratory, genetic, or ultrasound parameters and VTEE risk factors. The results of the multivariate stepwise regression analysis demonstrated that female gender, chronic heart failure (CHF), VTEE symptom duration <28 days, and thrombus “size” >< 28 days, and thrombus “size” < 6 points were independent predictors of D-dimer elevation in the acute period of DVT/PE. Conclusion. D-dimer levels, measured 32 (23–44) days after the development of DVT/PE symptoms, were elevated in 74% of the patients. D-dimer elevation in the acute period of VTEE was associated with female gender, CHF, “age” and “size” of the thrombus

The Sun and heliosphere explorer - the Interhelioprobe mission

International audienceThe Interhelioprobe mission aims to investigate the inner heliosphere and the Sun from close distances (up to 0.3 AU) and from out of the ecliptic plane (up to 30°). In this paper we present the relevance of the mission and its main scientific objectives, describe the scientific payload, ballistic scenario and orbits of the spacecraft. Possibilities of scientific cooperation with other solar and heliospheric space missions are also mentioned