BUILDING A START-UP ECOSYSTEM IN HO CHI MINH CITY, VIETNAM FOR SUSTAINABLE DEVELOPMENT

Developing a start-up ecosystem, and creating a favorable environment to promote and support the process of forming and developing fast-growing businesses based on exploiting intellectual property, technology, and business models.  New business model is an important direction of Vietnam and Ho Chi Minh City.  This article studies the current situation and proposes some oriented solutions for the goal of perfecting the startup ecosystem in Ho Chi Minh City in the current integration conditions

BUILDING A START-UP ECOSYSTEM IN HO CHI MINH CITY, VIETNAM FOR SUSTAINABLE DEVELOPMENT

Developing a start-up ecosystem, and creating a favorable environment to promote and support the process of forming and developing fast-growing businesses based on exploiting intellectual property, technology, and business models.  New business model is an important direction of Vietnam and Ho Chi Minh City.  This article studies the current situation and proposes some oriented solutions for the goal of perfecting the startup ecosystem in Ho Chi Minh City in the current integration conditions

HO CHI MINH’S THOUGHT ON EDUCATION AND ITS MEANING FOR HUMAN RESOURCES TRAINING TO MEET THE REQUIREMENTS OF THE FORTH INDUSTRIAL REVOLUTION

Choosing the path of proletarian revolution to liberate the nation, emancipate classes, and liberate people, Ho Chi Minh has placed top attention on changing and developing the country's education, considering it the basic foundation to change ideologies, awaken the national consciousness among the people, and make the revolution a complete success. Ho Chi Minh emphasized the role of education, considering it as one of the factors determining the success of realizing the goal of building a new Vietnam. Inheriting and applying Ho Chi Minh's thought in the cause of renewal, the Communist Party of Vietnam has always paid attention to building and developing education to meet the requirements of industrialization and modernization of the country. In the period of international economic integration, meeting the requirements of the fourth industrial revolution, the training of high-quality human resources has become even more urgent. Ho Chi Minh's thought on education has become more and more practical in training, developing and using quality human resources to serve the country's socio-economic goals, and realize the goal of "rich people, a strong country, equal, democratic and civilized society". Article visualizations

The ideology of “taking people as the root” of the Ly dynasty in Vietnam

Ideology is always an issue that plays an important role in the life of a society, and that ideology also greatly influences the process of ruling the country of dynasties in the history. Unlike previous dynasties, which lasted only a few decades, the Ly dynasty represents a flourishing period of feudalism lasting more than 200 years. A major event was that King Ly Thanh Tong changed the country name from Dai Co Viet to Dai Viet in 1054, ushering in a brilliant era in Vietnamese history. The ideology of “taking people as the root” of Vietnamese feudal dynasties highlights the unyielding and indomitable fighting spirit for the right to enjoy independence and freedom in the old land of Giao Chi and Cuu Chan, which later was Dai Viet and is now Vietnam. It also reflects the desire for people to live in peace and harmony. This articles focuses on studying the ideology of “taking people as the root” through the reign of kings of the Ly dynasty in Vietnam. From there, the article points out the achievements and limitations in the process of taking care of people, as well as historical lessons for the development of the country today

Optimization of L-asparaginase production from Escherichia coli using response surface methodology

Among the antitumor drugs, bacterial enzyme L-asparaginase has been employed as the most effective chemotherapeutic agent in pediatric oncotherapy especially for acute lymphoblastic leukemia. In previous study, the L-asparaginase from Erwinia chrysanthermy was expressed in Escherichia coli BL21(DE3). The recombinant L-asparaginase was produced from recombinant E.coli BL21(DE3) under different cultivation conditions (inducer concentration, inoculum concentration and KH2PO4 concentration). The optimized conditions by response surface methodology using face centered central composite design. The analysis of variance coupled with larger value of R2 (0.9) showed that the quadratic model used for the prediction was highly significant (p 0.05). Under the optimized conditions, the model produced L-asparaginase activity of 123.74 U/ml at 1.03 mM IPTG, 3% (v/v) inoculum and 0.5% (w/v) KH2PO4. Recombinant protein was purified by two step using gel filtration and DEAE chromatography. The purified L-asparaginase had a molecular mass of 37 kDa with specific activity of 462 U/mg and identified by MALDI-TOF mass spectrometry. Results of MALDI-TOF analysis confirmed that recombinant protein was L-asparaginase II. Recombinant L-asparaginase has antiproliferative activity with K562 cell line. In conclusion, this study has innovatively developed cultivation conditions for better production of recombinant L-asparaginase in shake flask culture

Expression, purification and evaluation of recombinant L-asparaginase inmehthylotrophic yeast Pichia pastoris: Expression, purification and evaluation of recombinant L-asparaginase in mehthylotrophic yeast Pichia pastoris: Research article

L-asparaginase (EC 3.5.1.1), a therapeutic enzyme used in the treatment of childhood acute lymphoblastic leukemia (ALL). Hence, the goal of this work is study the expression and evaluation of hydrolysis activity of native sequence (X12746) encoding for L-asparaginase from Erwinia chrysanthemi NCPBB1125 in the popular expression system Pichia pastoris. The sequence of asn encoded for mature protein was expressed in P. pastoris SMD1168 and X33. SDS-PAGE analysis showed recombinant L-asparaginase was secreted efficiently. Stable and high hydrolysis activity of extracellular L-asparaginase in P. pastoris SMD1168 making it a potential candidate to produce recombinant protein. After purification, a specific band whose appearance approximately 45 kDa indicating the glycosylated protein with specific activity by 6.251 Umg-1 and about 3 folds purifications.L-asparaginase (EC 3.5.1.1), một loại enzyme được sử dụng trong điều trị bệng ung thư bạch cầu mãn tính ở trẻ em. Mục tiêu của nghiên cứu này là biểu hiện và đánh giá hoạt tính thủy phân của L-asparaginase mã hóa bởi đoạn gene (X12746) tương ứng từ Erwinia chrysanthemi NCPBB1125 được biểu hiện trong nấm men Pichia pastoris. Gene đã được cắt signal peptide và biểu hiện trong P. pastoris SMD1168 and X33. Qua phân tích kết quả điện di SDS-PAGE của môi trường sau lên men, L-asparaginase tái tổ hợp được tìm thấy trong dịch ngoại bào của P. pastoris. Với khả năng sản xuất protein có hoạt tính cao hơn so với chủng P. pastoris X33, SMD1168 được lựa chọn để biểu hiện L-asparaginase tái tổ hợp. Sau khi tinh sạch, sự xuất hiện của một băng có kích khối lượng phân tử xấp xỉ 45 kDa trên điện di SDS-PAGE cho thấy protein tái tổ hợp đã bị glycosyl hóa với hoạt tính riêng 6.251 Umg-1 và đạt độ sạch 3.471 lần

The Distribution of Microplastics in Beach Sand in Tien Giang Province and Vung Tau City, Vietnam

Microplastics threaten the ecosystem because of undesirable properties such as non-biodegradability, easy-to-absorb persistant organic compounds, etc. They are found worldwide in marine, fresh water and beach sand environments. In this study, microplastics in beach sand samples from two sites in Tien Giang province and two sites in Vung Tau city were investigated. The results showed that the microplastics amount was 0 to 295 pieces/kg dry sand and they mainly distributed near estuarine areas. Microplastics were more prevalent at bathing sites than non-bathing sites. In Tien Giang fragments were the most dominant among the three types of shapes (fragments, fibers, granules) at 60.2%. In Vung Tau granules were most prevalent at 71.7%. The composition of the plastics was confirmed by Fourier-transform infrared spectroscopy. It was revealed that PE, PP and PS were the main types of plastics found in the sampling sites.

Perceptual Learning Style Preference for Medical Terminology: A Case Study of 20 ESP Students

Due to the globalization, there has been a great demand for learning English for Specific Purposes (ESP) in different fields. How to teach medical terminology effectively to pre-service medical professionals is one of the main challenges that ESP instructors encounter in their English in Medicine classrooms. A variety of factors, including but are not limited to student learning style preference, prior knowledge, classroom facilities should be considered. In this study, we conducted a case study of 20 students in an ESP class to explore their learning style preference. This study employed two data collection instruments: questionnaire and interview. Data analysis interestingly revealed that the location of students’ secondary education has an influence on their perceptual learning style preference of medical terminology at tertiary level. Drawing on the results, this study argues for a balance between student learning preference and teaching mythology. Keywords: ESP, perceptual learning style preference, medical terminology DOI: 10.7176/JLLL/66-06 Publication date:March 31st 202