340 research outputs found
Development Plan for the Fuel Cycle Simulator
The Fuel Cycle Simulator (FCS) project was initiated late in FY-10 as the activity to develop a next generation fuel cycle dynamic analysis tool for achieving the Systems Analysis Campaign 'Grand Challenge.' This challenge, as documented in the Campaign Implementation Plan, is to: 'Develop a fuel cycle simulator as part of a suite of tools to support decision-making, communication, and education, that synthesizes and visually explains the multiple attributes of potential fuel cycles.
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Metrics Evolution in an Energy Research & Development Program
All technology programs progress through three phases: Discovery, Definition, and Deployment. The form and application of program metrics needs to evolve with each phase. During the discovery phase, the program determines what is achievable. A set of tools is needed to define program goals, to analyze credible technical options, and to ensure that the options are compatible and meet the program objectives. A metrics system that scores the potential performance of technical options is part of this system of tools, supporting screening of concepts and aiding in the overall definition of objectives. During the definition phase, the program defines what specifically is wanted. What is achievable is translated into specific systems and specific technical options are selected and optimized. A metrics system can help with the identification of options for optimization and the selection of the option for deployment. During the deployment phase, the program shows that the selected system works. Demonstration projects are established and classical systems engineering is employed. During this phase, the metrics communicate system performance. This paper discusses an approach to metrics evolution within the Department of Energy's Nuclear Fuel Cycle R&D Program, which is working to improve the sustainability of nuclear energy
Environmental transmission of Toxoplasma gondii: Oocysts in water, soil and food
Toxoplasma gondii is a zoonotic protozoan parasite that can cause morbidity and mortality in humans, domestic animals, and terrestrial and aquatic wildlife. The environmentally robust oocyst stage of T. gondii is fundamentally critical to the parasite\u27s success, both in terms of its worldwide distribution as well as the extensive range of infected intermediate hosts. Despite the limited definitive host species (domestic and wild felids), infections have been reported on every continent, and in terrestrial as well as aquatic environments. The remarkable resistance of the oocyst wall enables dissemination of T. gondii through watersheds and ecosystems, and long-term persistence in diverse foods such as shellfish and fresh produce. Here, we review the key attributes of oocyst biophysical properties that confer their ability to disseminate and survive in the environment, as well as the epidemiological dynamics of oocyst sources including domestic and wild felids. This manuscript further provides a comprehensive review of the pathways by which T. gondii oocysts can infect animals and people through the environment, including in contaminated foods, water or soil. We conclude by identifying critical control points for reducing risk of exposure to oocysts as well as opportunities for future synergies and new directions for research aimed at reducing the burden of oocyst-borne toxoplasmosis in humans, domestic animals, and wildlife
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Guidance for Environmental Mangement Science and Technology Roadmapping
Science and technology roadmapping is a planning process to help identify technical capabilities needed for both project- and program-level cleanup efforts, map them into technology alternatives, and develop plans to ensure that the required scientific knowledge and tools will be available when needed. Application of science and technology roadmapping within Invironmental Management (EM) requires significant flexibility to accommodate the variations between different projects and programs and the different levels of roadmapping application. The author has provided direct support to EM’s Office of Science and Technology (OST) in the development of draft guidance for science and technology roadmapping in EM. This paper provides a summary of this guidance and a synopsis of lessons learned from the application of roadmapping to a number of EM projects and programs
Point Process Algorithm: A New Bayesian Approach for Planet Signal Extraction with the Terrestrial Planet Finder
The capability of the Terrestrial Planet Finder Interferometer (TPF-I) for
planetary signal extraction, including both detection and spectral
characterization, can be optimized by taking proper account of instrumental
characteristics and astrophysical prior information. We have developed the
Point Process Algorithm (PPA), a Bayesian technique for extracting planetary
signals using the sine-chopped outputs of a dual nulling interferometer. It is
so-called because it represents the system being observed as a set of points in
a suitably-defined state space, thus providing a natural way of incorporating
our prior knowledge of the compact nature of the targets of interest. It can
also incorporate the spatial covariance of the exozodi as prior information
which could help mitigate against false detections. Data at multiple
wavelengths are used simultaneously, taking into account possible spectral
variations of the planetary signals. Input parameters include the RMS
measurement noise and the a priori probability of the presence of a planet. The
output can be represented as an image of the intensity distribution on the sky,
optimized for the detection of point sources. Previous approaches by others to
the problem of planet detection for TPF-I have relied on the potentially
non-robust identification of peaks in a "dirty" image, usually a correlation
map. Tests with synthetic data suggest that the PPA provides greater
sensitivity to faint sources than does the standard approach (correlation map +
CLEAN), and will be a useful tool for optimizing the design of TPF-I.Comment: 17 pages, 6 figures. AJ in press (scheduled for Nov 2006
Gaugino Masses in Modular Invariant Supergravity
We calculate gaugino masses in string-derived models with hidden-sector
gaugino condensation. The linear multiplet formulation for the dilaton
superfield is used to implement perturbative modular invariance. The
contribution arising from quantum effects in the observable sector includes the
term recently found in generic supergravity models. A much larger contribution
is present if matter fields with Standard Model gauge couplings also couple to
the Green-Schwarz counter term. We comment on the relation of our K\"ahler U(1)
superspace formalism to other calculations.Comment: 15 pages, full postscript also available from
http://phyweb.lbl.gov/theorygroup/papers/43259.p
Interrelation of preventive care benefits and shared costs under the Affordable Care Act (ACA)
With the implementation of the Affordable Care Act (ACA), access to insurance and coverage of preventive care
services has been expanded. By removing the barrier of shared costs for preventive care, it is expected that an increase
in utilization of preventive care services will reduce the cost of chronic diseases. Early detection and treatment is
anticipated to be less costly than treatment at full onset of chronic conditions. One concern of early detection of
disease is the cost to treat. In reality, the confluence of early detection may result in greater overall expenditures. Even
with improved access to preventive care benefits, cost-sharing of other health services remains a major component
of insurance plans. In order to treat identified conditions or diseases, cost-sharing comes into play. With the
greater adoption of cost-sharing insurance plans, expenditures on the part of enrollee are anticipated to rise. Once
the healthcare recipients realize the implication of early identification and resultant treatment costs, enrollment in
preventive care may decline. Healthcare legislation and regulation should consider the full spectrum of care and the
microeconomic costs associated with preventive treatment. Although the system at large may not realize the immediate
impact, behavioral shifts on the part of healthcare consumers may alter healthcare. Rather than the current status quo
of treating presenting conditions, preventive treatment is largely anticipated to require more resources and may impact
the consumer’s financial capacity. This report will explore how these two concepts are co-dependent, and highlight the
need for continued refor
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Roadmapping - A Tool for Resolving Science and Technology Issues Related to Processing, Packaging, and Shipping Nuclear Materials and Waste
Roadmapping is an effective methodology to identify and link technology development and deployment efforts to a program's or project's needs and requirements. Roadmapping focuses on needed technical support to the baselines (and to alternatives to the baselines) where the probability of success is low (high uncertainty) and the consequences of failure are relatively high (high programmatic risk, higher cost, longer schedule, or higher ES&H risk). The roadmap identifies where emphasis is needed, i.e., areas where investments are large, the return on investment is high, or the timing is crucial. The development of a roadmap typically involves problem definition (current state versus the desired state) and major steps (functions) needed to reach the desired state. For Nuclear Materials (NM), the functions could include processing, packaging, storage, shipping, and/or final disposition of the material. Each function is examined to determine what technical development would be needed to make the function perform as desired. This requires a good understanding of the current state of technology and technology development and validation activities to ensure the viability of each step. In NM disposition projects, timing is crucial! Technology must be deployed within the project window to be of value. Roadmaps set the stage to keep the technology development and deployment focused on project milestones and ensure that the technologies are sufficiently mature when needed to mitigate project risk and meet project commitments. A recent roadmapping activity involved a 'cross-program' effort, which included NM programs, to address an area of significant concern to the Department of Energy (DOE) related to gas generation issues, particularly hydrogen. The roadmap that was developed defined major gas generation issues within the DOE complex and research that has been and is being conducted to address gas generation concerns. The roadmap also provided the basis for sharing ''lessons learned'' from R&D efforts across DOE programs to increase efficiency and effectiveness in addressing gas generation issues. The gas generation roadmap identified pathways that have significant risk, indicating where more emphasis should be placed on contingency planning. Roadmapping further identified many opportunities for sharing of information and collaboration. Roadmapping will continue to be useful in keeping focused on the efforts necessary to mitigate the risk in the disposition pathways and to respond to the specific needs of the sites. Other areas within NM programs, including transportation and disposition of orphan and other nuclear materials, are prime candidates for additional roadmapping to assure achievement of timely and cost effective solutions for the processing, packaging, shipping, and/or final disposition of nuclear materials
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Science and Technology Roadmapping to Support Project Planning
Disciplined science and technology roadmapping provides a framework to coordinate research and development activities with project objectives. This case-history paper describes initial project technology needs identification, assessment and R&D ranking activities supporting characterization of 781 waste tanks requiring a 'hazardous waste determination' or 'verification of empty' decision to meet an Idaho state Voluntary Consent Order
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