40 research outputs found

    Using concept maps as an alternative assessment tool and investigation by comparing with multiple choice tests

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    Canbazoğlu Bilici, Sedef ( Aksaray, Yazar )Bu araştırmanın temel amacı fen ve teknoloji derslerinde kavram haritalarının değerlendirme aracı olarak kullanımının incelenmesidir. Bu temel amaç doğrultusunda araştırmada, kavram haritalarının puanlandırılması ve kavram haritalarında kullanılan kavramlar ile aynı kavramlara ilişkin çoktan seçmeli test sorularına verilen öğrenci cevaplarının karşılaştırılması amaçlanmıştır. Araştırma 7.sınıfta öğrenim gören 30 öğrenci ile gerçekleştirilmiştir. Araştırma sonucunda öğrencilerin kavram haritalarında konu ile ilgili anahtar kavramları birbirleriyle ilişkilendirmede ve kavramlar arası bağlantılar oluşturmada zorlanırken, aynı kavramlara ilişkin çoktan seçmeli test sorularını doğru cevapladıkları tespit edilmiştir. Yapısal ve ilişkisel puanlama yöntemleri ile değerlendirilen kavram haritalarından elde edilen puanlar, iki puanlama tekniği arasında anlamlı ve yüksek bir korelasyon olduğunu göstermiştir.The main purpose of this research is to investigate the use of concept maps as an alternative assessment tool in Science and Technology courses. In accordance with this main purpose, the study aimed at scoring concept maps, and comparing concepts in concept maps with the answers given by students to multiple choice test questions related to the same concepts. The participants of this research were 30 seventh-grade students. The results showed that students had difficulties in making connections between the key concepts and creating linking phrases. On the other hand, they answered the test questions related to the same concepts in concept maps correctly. Using structural and relational scoring methods to evaluate the concept maps, the scores showed a significant and strong correlation between these two scoring methods

    A Case of Pseudomonas stutzeri Bacteremia in a Patient with Hematologic Malignancy

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    Pseudomonas stutzeri is a gram-negative bacterium, ubiquitous in the environment, and it also causes opportunistic infections in humans. We describe a case with hematologic malignancy, peripheral T-cell lymphoma. The patient was hospitalized for antineoplastic chemotherapy. In the course of treatment, the patient acquired P. stutzeri, most probably from the hospital environment and bacteremia of P. stutzeri and then pneumonia developed. The bacteria were identified based on conventional microbiological identification techniques. Even though P. stutzeri is ubiquitous in the environment and a rare human pathogen, it should always be considered as a bacterial agent for opportunistic infections in hospitalized patients, especially immune depressed patients

    Prognostic importance of RASSF2 expression in patients with gastric cancer who had undergone radical gastrectomy

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    WOS: 000375788300009PubMed ID: 26459248Although Ras-association domain family of gene 2 (RASSF2) has been shown to undergo promoter methylation at high frequency in some cancer types and in brain metastases, its clinical utility as a useful prognostic molecular marker remains unclear in gastric cancer. Prognostic significance of RASSF2 expression was retrospectively analysed by immunohistochemically in 105 patients with gastric cancer who underwent curative gastrectomy. Low RASSF2 expression was detected in 58 (55 %) patients, whereas 47 patients (45 %) had high RASSF2 expression. Lymph node involvement, pT stage, TNM stage, vascular invasion, perineural invasion and the presence of recurrence were found to be significantly related to RASSF2 expression levels. Low PRL-3 expression was closely correlated with lymph node metastasis (p = 0.001), advanced pT stage (p = 0.021), advanced TNM stage (p < 0.001), the presence of vascular invasion (p < 0.001), perineural invasion (p = 0.018) and high prevalence of recurrence (p = 0.003) compared with high RASSF2 expression. The median disease-free survival (DFS) time for patients with low RASSF2 expression was significantly worse than that of patients with high RASSF2 expression (10.2 vs. 50.6 months, p < 0.001). In addition, patients with high RASSF2 expression had the higher overall survival (OS) interval compared to patients with low RASSF2 expression (NR vs. 14.9 months, p < 0.001). In the multivariate analysis, the rate of RASSF2 expression levels was an independent prognostic factor, for DFS [p < 0.001, HR 0.12 (0.10-0.88)] and OS [p < 0.001, HR 0.10 (0.04-0.46)], as were pT stage and TNM stage, respectively. RASSF2 may be an important molecular marker for carcinogenesis, prognosis and progression in gastric cancer, but the potential value of RASSF2 expression as a useful molecular marker in gastric cancer progression should be evaluated, comprehensively. It would be possible to develop treatments targeting RASSF2 and advance new treatment strategies for gastric cancer

    Clips migration to duodenum as a rare complication of laparoscopic cholecystectomy

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    WOS: 000404541200016Endoclip migration into the duodenum is an extremely rare complication of laparoscopic cholecystectomy. The patients usually present with bleeding ulcer. Here we report a 65-year-old female patient with a complaint of abdominal pain and dyspepsia due to clip migration into the duodenum after laparoscopic cholecystectomy secondary to symptomatic cholelithiasis 15 months previously. Ultrasonography and liver function tests were normal. Endoscopy showed metal clips in the second part of duodenum. The clips were removed endoscopically. No active bleeding was noted. In this case report, we present diagnosis and management of clips migration into wall of duodenum as a complication of laparoscopic cholecystectomy

    Clips migration to duodenum as a rare complication of laparoscopic cholecystectomy

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    Laparoskopik kolesistektomi sonrası, ameliyatta kullanılan metal kliplerin duedonum duvarına hareketle çıkıntı oluşturmaları nadir görülen bir komplikasyondur. Genellikle kanamalı ülsere neden olurlar. Kliniğimize karın ağrısı, hazımsızlık ve mide ekşimesi şikayetiyle başvuran 65 yaşında bayan hastaya yapılan üst gastrointestinal endoskopide duedonum bulbus tabanında yerleşik metal klip izlendi. Yapılan skopide üst üste binmiş iki klip olduğu görüldü. Metal klipler endoskopik olarak çıkarıldı. Olgunun öyküsünde 15 ay önce semptomatik kolelitiazis nedeniyle laparoskopik kolesistektomi yapıldığı öğrenildi. Bu olgu sunumunda laparoskopik kliplerlerin nadir olarak duedonum duvarına çıkıntı oluşturmasına yönelik yaklaşım ile ilgili bilgi verildiEndoclip migration into the duodenum is an extremely rare complication of laparoscopic cholecystectomy. The patients usually present with bleeding ulcer. Here we report a 65-year-old female patient with a complaint of abdominal pain and dyspepsia due to clip migration into the duodenum after laparoscopic cholecystectomy secondary to symptomatic cholelithiasis 15 months previously. Ultrasonography and liver function tests were normal. Endoscopy showed metal clips in the second part of duodenum. The clips were removed endoscopically. No active bleeding was noted. In this case report, we present diagnosis and management of clips migration into wall of duodenum as a complication of laparoscopic cholecystectom

    Correlation of Caveolin-1 Expression with Prognosis in Patients with Gastric Cancer after Gastrectomy

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    Background: Upregulation of caveolin-1 (Cav-1) expression is correlated with histopathological grade and poor prognosis in several human cancers. However, in gastric cancer, its clinical utility as a useful prognostic molecular marker remains unclear. Methods: The prognostic importance of Cav-1 expression was retrospectively analyzed by immunohistochemistry in 148 patients with gastric cancer who had undergone radical gastrectomy. Results: Cav-1 expression was positive in 23 (15.5%) patients and negative in 125 (84.5%) patients. Tumor location, tumor grade, lymph node involvement, pT stage, pTNM stage, and the presence of recurrence were found to be significantly associated with Cav-1 expression. The median disease-free survival (DFS) of patients with negative Cav-1 expression was significantly better than that of patients with positive Cav-1 expression (not reached vs. 10.2 months, p < 0.001). Moreover, patients with positive Cav-1 expression had a worse median overall survival (OS) compared to patients with negative Cav-1 expression (14.2 vs. 40.3 months, p = 0.004). In the multivariate analysis, Cav-1 expression (positive vs. negative) was an independent prognostic factor for DFS (p < 0.001, hazard ratio (HR) 2.58) and OS (p = 0.031, HR 1.87), as was lymph node metastasis. Conclusion: Our results suggest that positive Cav-1 expression is associated with progression and poor prognosis in gastric cancer patients after radical gastrectomy. Targeting Cav-1 would be a potential option for future gastric cancer treatment. (C) 2017 S. Karger GmbH, Freibur
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