Vergelijking van vangsten en brandstofverbruik van kotters vissend met conventionele en SumWing-boomkorren

De SumWing is een innovatief vistuig dat ontwikkeld wordt om brandstof te besparen in de boomkorvisserij op platvis en bij te dragen aan het verminderen van ongewenste ecosysteem effecten om zodoende een toekomstperspectief voor deze tak van visserij te bewerkstelligen. De ontwikkeling startte in 2006 in het kader van de Taskforce Duurzame Visserijontwikkeling en wordt momenteel als project onder begeleiding van het Visserij Innovatie Platvorm (VIP) voortgezet. Een indicatieve berekening van de penetratiediepte van een SumWing-tuig geeft een vermindering van ca. 10% t.o.v. een boomkortuig met sloffen onder de aanname dat de wekkers gelijk zijn. Combinatie van de SumWing en de pulskor zou dit percentage kunnen verhogen tot 50% en is hierdoor een interessante optie om bodemimpact verder te verminderen

Measuring similarity between business process models. In:

Abstract. Quality aspects become increasingly important when business process modeling is used in a large-scale enterprise setting. In order to facilitate a storage without redundancy and an efficient retrieval of relevant process models in model databases it is required to develop a theoretical understanding of how a degree of behavioral similarity can be defined. In this paper we address this challenge in a novel way. We use causal footprints as an abstract representation of the behavior captured by a process model, since they allow us to compare models defined in both formal modeling languages like Petri nets and informal ones like EPCs. Based on the causal footprint derived from two models we calculate their similarity based on the established vector space model from information retrieval. We validate this concept with an experiment using the SAP Reference Model and an implementation in the ProM framework

Medically Unexplained Oropharyngeal Dysphagia at the University Hospital ENT Outpatient Clinic for Dysphagia: A Cross-Sectional Cohort Study

Medically unexplained oropharyngeal dysphagia (MUNOD) is a rare condition. It presents without demonstrable abnormalities in the anatomy of the upper aero-digestive tract and/or swallowing physiology. This study investigates whether MUNOD is related to affective or other psychiatric conditions. The study included patients with dysphagic complaints who had no detectible structural or physiological abnormalities upon swallowing examination. Patients with any underlying disease or disorder that could explain the oropharyngeal dysphagia were excluded. All patients underwent a standardized examination protocol, with FEES examination, the Hospital Anxiety and Depression Scale (HADS), and the Dysphagia Severity Scale (DSS). Two blinded judges scored five different FEES variables. None of the 14 patients included in this study showed any structural or physiological abnormalities during FEES examination. However, the majority did show abnormal piecemeal deglutition, which could be a symptom of MUNOD. Six patients (42.8%) had clinically relevant symptoms of anxiety and/or depression. The DSS scores did not differ significantly between patients with and without affective symptoms. Affective symptoms are common in patients with MUNOD, and their psychiatric conditions could possibly be related to their swallowing problems

A rule driven approach for developing adaptive service oriented business collaboration

Current composite web service development and management solutions, e.g. BPEL, do not cater for flexible and adaptive business collaborations due to their pre-defined and inflexible nature that precludes them accommodating business dynamics. In this paper we propose a rule driven approach for adaptive business collaboration development in which rules drive and govern the development process. We introduce the Business Collaboration Development Framework (BCDF), which provides enterprizes with the context to define their capabilities and business collaboration agreements. Subsequently, we explain how rules can drive and control the business collaboration development process to develop complete, correct and consistent business collaboration agreements that are conform the conditions under which parties wish to cooperate.12 page(s

Human Bocavirus NS1 and NS1-70 Proteins Inhibit TNF-α-Mediated Activation of NF-κB by targeting p65.

Human bocavirus (HBoV), a parvovirus, is a single-stranded DNA etiologic agent causing lower respiratory tract infections in young children worldwide. Nuclear factor kappa B (NF-κB) transcription factors play crucial roles in clearance of invading viruses through activation of many physiological processes. Previous investigation showed that HBoV infection could significantly upregulate the level of TNF-α which is a strong NF-κB stimulator. Here we investigated whether HBoV proteins modulate TNF-α-mediated activation of the NF-κB signaling pathway. We showed that HBoV NS1 and NS1-70 proteins blocked NF-κB activation in response to TNF-α. Overexpression of TNF receptor-associated factor 2 (TRAF2)-, IκB kinase alpha (IKKα)-, IκB kinase beta (IKKβ)-, constitutively active mutant of IKKβ (IKKβ SS/EE)-, or p65-induced NF-κB activation was inhibited by NS1 and NS1-70. Furthermore, NS1 and NS1-70 didn't interfere with TNF-α-mediated IκBα phosphorylation and degradation, nor p65 nuclear translocation. Coimmunoprecipitation assays confirmed the interaction of both NS1 and NS1-70 with p65. Of note, NS1 but not NS1-70 inhibited TNF-α-mediated p65 phosphorylation at ser536. Our findings together indicate that HBoV NS1 and NS1-70 inhibit NF-κB activation. This is the first time that HBoV has been shown to inhibit NF-κB activation, revealing a potential immune-evasion mechanism that is likely important for HBoV pathogenesis

Extremely bulky copper(I) complexes of [HB(3,5-{1-naphthyl}(2)pz)(3)](-) and [HB(3,5-{2-naphthyl}(2)pz)(3)](-) and their self-assembly on graphene

Metals in Catalysis, Biomimetics & Inorganic Material

Enhancing modeling and change support for process families through change patterns

The increasing adoption of process-aware information systems (PAISs), together with the variability of business processes (BPs), has resulted in large collections of related process model variants (i.e., process families). To effectively deal with process families, several proposals (e.g., C-EPC, Provop) exist that extend BP modeling languages with variability-specific constructs. While fostering reuse and reducing modeling efforts, respective constructs imply additional complexity and demand proper support for process designers when creating and modifying process families. Recently, generic and language independent adaptation patterns were successfully introduced for creating and evolving single BP models. However, they are not sufficient to cope with the specific needs for modeling and evolving process families. This paper suggests a complementary set of generic and language-independent change patterns specifically tailored to the needs of process families. When used in combination with existing adaptation patterns, change patterns for process families will enable the modeling and evolution of process families at a high-level of abstraction. Further, they will serve as reference for implementing tools or comparing proposals managing process families. © 2013 Springer-Verlag.This work has been developed with the support of MICINN under the Project EVERYWARE TIN2010-18011.Ayora Esteras, C.; Torres Bosch, MV.; Weber, B.; Reichert, M.; Pelechano Ferragud, V. (2013). Enhancing modeling and change support for process families through change patterns. En Enterprise, Business-Process and Information Systems Modeling, BPMDS 2013. Springer Verlag. 246-260. https://doi.org/10.1007/978-3-642-38484-4_18S246260van der Aalst, W.M.P., ter Hofstede, A.H.M., Barros, B.: Workflow Patterns. Distributed and Parallel Databases 14(1), 5–51 (2003)Aghakasiri, Z., Mirian-Hosseinabadi, S.H.: Workflow change patterns: Opportunities for extension and reuse. In: Proc. SERA 2009, pp. 265–275 (2009)Ayora, C., Torres, V., Reichert, M., Weber, B., Pelechano, V.: Towards run-time flexibility for process families: Open issues and research challenges. In: La Rosa, M., Soffer, P. (eds.) BPM 2012 Workshops. LNBIP, vol. 132, pp. 477–488. Springer, Heidelberg (2013)Ayora, C., Torres, V., Weber, B., Reichert, M., Pelechano, V.: Change patterns for process families. Technical Report, PROS-TR-2012-06, http://www.pros.upv.es/technicalreports/PROS-TR-2012-06.pdfDadam, P., Reichert, M.: The ADEPT project: a decade of research and development for robust and flexible process support. Com. Sci. - R&D 23, 81–97 (2009)Dijkman, R., La Rosa, M., Reijers, H.A.: Managing large collections of business process models - Current techniques and challenges. Comp. in Ind. 63(2), 91–97 (2012)Döhring, M., Zimmermann, B., Karg, L.: Flexible workflows at design- and runtime using BPMN2 adaptation patterns. In: Abramowicz, W. (ed.) BIS 2011. LNBIP, vol. 87, pp. 25–36. Springer, Heidelberg (2011)Gottschalk, F.: Configurable process models. Ph.D. thesis, Eindhoven University of Technology, The Netherlands (2009)Grambow, G., Oberhauser, R., Reichert, M.: Contextual injection of quality measures into software engineering processes. Intl. J. Adv. in Software 4, 76–99 (2011)Gschwind, T., Koehler, J., Wong, J.: Applying patterns during business process modeling. In: Dumas, M., Reichert, M., Shan, M.-C. (eds.) BPM 2008. LNCS, vol. 5240, pp. 4–19. Springer, Heidelberg (2008)Günther, C.W., Rinderle, S., Reichert, M., van der Aalst, W.M.P.: Change mining in adaptive process management systems. In: Meersman, R., Tari, Z. (eds.) OTM 2006. LNCS, vol. 4275, pp. 309–326. Springer, Heidelberg (2006)Hallerbach, A., Bauer, T., Reichert, M.: Context-based configuration of process variants. In: Proc. TCoB 2008, pp. 31–40 (2008)Hallerbach, A., Bauer, T., Reichert, M.: Capturing variability in business process models: the Provop approach. J. of Software Maintenance 22(6-7), 519–546 (2010)Kitchenham, B., Charters, S.: Guidelines for performing Systematic Literature Reviews in Software Engineering, Technical Report EBSE/EPIC–2007–01 (2007)Kulkarni, V., Barat, S., Roychoudhury, S.: Towards business application product lines. In: France, R.B., Kazmeier, J., Breu, R., Atkinson, C. (eds.) MODELS 2012. LNCS, vol. 7590, pp. 285–301. Springer, Heidelberg (2012)Küster, J.M., Gerth, C., Förster, A., Engels, G.: Detecting and resolving process model differences in the absence of a change log. In: Dumas, M., Reichert, M., Shan, M.-C. (eds.) BPM 2008. LNCS, vol. 5240, pp. 244–260. Springer, Heidelberg (2008)Küster, J.M., Gerth, C., Engels, G.: Dynamic computation of change operations in version management of business process models. In: Kühne, T., Selic, B., Gervais, M.-P., Terrier, F. (eds.) ECMFA 2010. LNCS, vol. 6138, pp. 201–216. Springer, Heidelberg (2010)Lanz, A., Weber, B., Reichert, M.: Time patterns for process-aware information systems. Requirements Engineering, 1–29 (2012)La Rosa, M., van der Aalst, W.M.P., Dumas, M., ter Hofstede, A.H.M.: Questionnaire-based variability modeling for system configuration. Software and System Modeling 8(2), 251–274 (2009)Lerner, B.S., Christov, S., Osterweil, L.J., Bendraou, R., Kannengiesser, U., Wise, A.: Exception Handling Patterns for Process Modeling. IEEE Transactions on Software Engineering 36(2), 162–183 (2010)Li, C., Reichert, M., Wombacher, A.: Mining business process variants: Challenges, scenarios, algorithms. Data Knowledge & Engineering 70(5), 409–434 (2011)Marrella, A., Mecella, M., Russo, A.: Featuring automatic adaptivity through workflow enactment and planning. In: Proc. CollaborateCom 2011, pp. 372–381 (2011)Müller, D., Herbst, J., Hammori, M., Reichert, M.: IT support for release management processes in the automotive industry. In: Dustdar, S., Fiadeiro, J.L., Sheth, A.P. (eds.) BPM 2006. LNCS, vol. 4102, pp. 368–377. Springer, Heidelberg (2006)Reichert, M., Weber, B.: Enabling flexibility in process-aware information systems: challenges, methods, technologies. Springer (2012)Reinhartz-Berger, I., Soffer, P., Sturm, A.: Organizational reference models: supporting an adequate design of local business processes. IBPIM 4(2), 134–149 (2009)Rosemann, M., van der Aalst, W.M.P.: A configurable reference modeling language. Information Systems 32(1), 1–23 (2007)Russell, N., ter Hofstede, A.H.M., Edmond, D., van der Aalst, W.M.P.: Workflow data patterns. Technical Report FIT-TR-2004-01, Queensland Univ. of Technology (2004)Russell, N., ter Hofstede, A.H.M., Edmond, D., van der Aalst, W.M.P.: Workflow resource patterns. Technical Report WP 127, Eindhoven Univ. of Technology (2004)Russell, N., van der Aalst, W.M.P., ter Hofstede, A.H.M.: Workflow Exception Patterns. In: Martinez, F.H., Pohl, K. (eds.) CAiSE 2006. LNCS, vol. 4001, pp. 288–302. Springer, Heidelberg (2006)Smirnov, S., Weidlich, M., Mendling, J., Weske, M.: Object-sensitive action patterns in process model repositories. In: Muehlen, M.z., Su, J. (eds.) BPM 2010 Workshops. LNBIP, vol. 66, pp. 251–263. Springer, Heidelberg (2011)Weber, B., Reichert, M., Rinderle-Ma, S.: Change patterns and change support features - Enhancing flexibility in process-aware information systems. Data Knowledge & Engineering 66, 438–466 (2008)Weber, B., Sadiq, S., Reichert, M.: Beyond rigidity - dynamic process lifecycle support. Computer Science 23, 47–65 (2009)Weber, B., Reichert, M., Reijers, H.A., Mendling, J.: Refactoring large process model repositories. Computers in Industry 62(5), 467–486 (2011

Livestock production: recent trends, future prospects

The livestock sector globally is highly dynamic. In developing countries, it is evolving in response to rapidly increasing demand for livestock products. In developed countries, demand for livestock products is stagnating, while many production systems are increasing their efficiency and environmental sustainability. Historical changes in the demand for livestock products have been largely driven by human population growth, income growth and urbanization and the production response in different livestock systems has been associated with science and technology as well as increases in animal numbers. In the future, production will increasingly be affected by competition for natural resources, particularly land and water, competition between food and feed and by the need to operate in a carbon-constrained economy. Developments in breeding, nutrition and animal health will continue to contribute to increasing potential production and further efficiency and genetic gains. Livestock production is likely to be increasingly affected by carbon constraints and environmental and animal welfare legislation. Demand for livestock products in the future could be heavily moderated by socio-economic factors such as human health concerns and changing socio-cultural values. There is considerable uncertainty as to how these factors will play out in different regions of the world in the coming decades