Thermische Charakterisierung von keramischen Schwammstrukturen für verfahrenstechnische Apparate

In dieser Arbeit wurden Schwämme aus Al2O3, Mullit und oxidisch gebundenem SiC hinsichtlich ihrer Impuls- und Wärmetransporteigenschaften experimentell untersucht. Zur Auslegung chemischer Apparate nach dem heterogenen oder dem homogenen Modell wurden für folgende wärmetechnisch interessanten Parameter allgemeingültige, dimensionslose Korrelationen abgeleitet: Druckverlust, Wärmeübergangskoeffizient zwischen Fluid und Feststoffgerüst, Ruhe- sowie axiale und radiale Zweiphasen-Wärmeleitfähigkeit

New techniques for deeper insights

To gain deeper insights into the old questions about the influence of water on radiation interaction with DNA, new spectroscopic techniques had to be applied

In situ monitoring of the influence of water on DNA radiation damage by near-ambient pressure X-ray photoelectron spectroscopy

Ionizing radiation damage to DNA plays a fundamental role in cancer therapy. X-ray photoelectron-spectroscopy (XPS) allows simultaneous irradiation and damage monitoring. Although water radiolysis is essential for radiation damage, all previous XPS studies were performed in vacuum. Here we present near-ambient-pressure XPS xperiments to directly measure DNA damage under water atmosphere. They permit in-situ monitoring of the effects of radicals on fully hydrated double-stranded DNA. The results allow us to distinguish direct damage, by photons and secondary low-energy electrons (LEE), from damage by hydroxyl radicals or hydration induced modifications of damage pathways. The exposure of dry DNA to x-rays leads to strand-breaks at the sugar-phosphate backbone, while deoxyribose and nucleobases are less affected. In contrast, a strong increase of DNA damage is observed in water, where OH-radicals are produced. In consequence, base damage and base release become predominant, even though the number of strand-breaks increases further

Depression Care Management: Can Employers Purchase Improved Outcomes?

Fourteen vendors are currently selling depression care management products to US employers after randomized trials demonstrate improved work outcomes. The research team interviewed 10 (71.4%) of these vendors to compare their products to four key components of interventions demonstrated to improve work outcomes. Five of 10 depression products incorporate all four key components, three of which are sold by health maintenance organizations (HMOs); however, HMOs did not deliver these components at the recommended intensity and/or duration. Only one product delivered by a disease management company delivered all four components of care at the recommended intensity and duration. This “voltage drop,” which we anticipate will increase with product implementation, suggests that every delivery system should carefully evaluate the design of its depression product before implementation for its capacity to deliver evidence-based care, repeating these evaluations as new evidence emerges

Nonlinear Bayesian Estimation with Convex Sets of Probability Densities

This paper presents a theoretical framework for Bayesian estimation in the case of imprecisely known probability density functions. The lack of knowledge about the true density functions is represented by sets of densities. A formal Bayesian estimator for these sets is introduced, which is intractable for infinite sets. To obtain a tractable filter, properties of convex sets in form of convex polytopes of densities are investigated. It is shown that pathwise connected sets and their convex hulls describe the same ignorance. Thus, an exact algorithm is derived, which only needs to process the hull, delivering tractable results in the case of a proper parametrization. Since the estimator delivers a convex hull of densities as output, the theoretical grounds are laid for deriving efficient Bayesian estimators for sets of densities. The derived filter is illustrated by means of an example

Wall-liquid and wall-crystal interfacial free energies via thermodynamic integration: A molecular dynamics simulation study

A method is proposed to compute the interfacial free energy of a Lennard-Jones system in contact with a structured wall by molecular dynamics simulation. Both the bulk liquid and bulk face-centered-cubic crystal phase along the (111) orientation are considered. Our approach is based on a thermodynamic integration scheme where first the bulk Lennard-Jones system is reversibly transformed to a state where it interacts with a structureless flat wall. In a second step, the flat structureless wall is reversibly transformed into an atomistic wall with crystalline structure. The dependence of the interfacial free energy on various parameters such as the wall potential, the density and orientation of the wall is investigated. The conditions are indicated under which a Lennard-Jones crystal partially wets a flat wall.Comment: 15 pages, 11 figure