139 research outputs found

    Levels and causes of household food and nutrition insecurity in dryland Kenya

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    Ensuring food and nutrition security in the drylands of sub-Saharan Africa is a critical challenge. Often, information on the level of insecurity is either scanty or unavailable. This paper looks at food and nutrition access at the household level and its determinants in two cases in one of the sub-Saharan African countries: Kenya. Data were collected from a repeat-visit survey of 50 households in two areas of Makueni District, located in the southern part of the country, during 1994–1996, a period that included ‘normal’ and drought seasons. Even in a season of normal rains, 32 to 42 per cent of households were food insecure, percentages that rose to 40 and 52 during drought. The annual incidence of food poverty was higher (46%) in the drier area than in the wetter area (36%). Food distribution among households, however, showed a reverse trend with the drier area having a Gini coefficient of 0.32 compared to 0.34 in the wetter area. Regressions were used to examine the causes of food and nutrition insecurity. Amongst the main factors improving food and nutrition security was earnings from off the farm. Households headed by women were more food secure than those headed by men, all other things being equal. These findings provide support for prioritising entitlements in terms of earnings and food prices in policy-making, rather than focusing on food production alone. They also indicate that there may be higher social returns to addressing issues of livelihoods associated with women rather than me

    Zona incerta neurons projecting to the ventral tegmental area promote action initiation towards feeding

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    Key pointsThe zona incerta (ZI) and ventral tegmental area (VTA) are brain areas that are both implicated in feeding behaviour. The ZI projects to the VTA, although it has not yet been investigated whether this projection regulates feeding.We experimentally (in)activated the ZI to VTA projection by using dual viral vector technology, and studied the effects on feeding microstructure, the willingness to work for food, general activity and body temperature.Activity of the ZI to VTA projection promotes feeding by facilitating action initiation towards food, as reflected in meal frequency and the willingness to work for food reward, without affecting general activity or directly modulating body temperature.We show for the first time that activity of the ZI to VTA projection promotes feeding, which improves the understanding of the neurobiology of feeding behaviour and body weight regulation.Both the zona incerta (ZI) and the ventral tegmental area (VTA) have been implicated in feeding behaviour. The ZI provides prominent input to the VTA, although it has not yet been investigated whether this projection regulates feeding. Therefore, we investigated the role of ZI to VTA projection neurons in the regulation of several aspects of feeding behaviour. We determined the effects of (in)activation of ZI to VTA projection neurons on feeding microstructure, food-motivated behaviour under a progressive ratio schedule of reinforcement, locomotor activity and core body temperature. To activate or inactivate ZI neurons projecting to the VTA, we used a combination of canine adenovirus-2 in the VTA, as well as Cre-dependent designer receptors exclusively activated by designer drugs (DREADD) or tetanus toxin (TetTox) light chain in the ZI. TetTox-mediated inactivation of ZI to VTA projection neurons reduced food-motivated behaviour and feeding by reducing meal frequency. Conversely, DREADD-mediated chemogenetic activation of ZI to VTA projection neurons promoted food-motivated behaviour and feeding. (In)activation of ZI to VTA projection neurons did not affect locomotor activity or directly regulate core body temperature. Taken together, ZI neurons projecting to the VTA exert bidirectional control overfeeding behaviour. More specifically, activity of ZI to VTA projection neurons facilitate action initiation towards feeding, as reflected in both food-motivated behaviour and meal initiation, without affecting general activity

    Policy actions required to improve nutrition for brain health

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    Brain health is a pressing global concern. Poor diet quality is a recognized major environmental risk factor for brain disorders and one of the few that is modifiable. There is substantial evidence that nutrition impacts brain development and brain health across the life course. So why then is the full potential of nutrition not utilized to improve brain function? This commentary, which is based on discussions of the European Brain Research Area BRAINFOOD cluster, aims to highlight the most urgent research priorities concerning the evidence base in the area of nutrition and brain health and identifies 3 major issues that need to be addressed: (1) increase causal and mechanistic evidence on the link between nutrition and brain health, (2) produce effective messages/education concerning the role of food for brain health, and (3) provide funding to support collaborative working across diverse stakeholders

    Differential cross section and recoil polarization measurements for the gamma p to K+ Lambda reaction using CLAS at Jefferson Lab

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    We present measurements of the differential cross section and Lambda recoil polarization for the gamma p to K+ Lambda reaction made using the CLAS detector at Jefferson Lab. These measurements cover the center-of-mass energy range from 1.62 to 2.84 GeV and a wide range of center-of-mass K+ production angles. Independent analyses were performed using the K+ p pi- and K+ p (missing pi -) final-state topologies; results from these analyses were found to exhibit good agreement. These differential cross section measurements show excellent agreement with previous CLAS and LEPS results and offer increased precision and a 300 MeV increase in energy coverage. The recoil polarization data agree well with previous results and offer a large increase in precision and a 500 MeV extension in energy range. The increased center-of-mass energy range that these data represent will allow for independent study of non-resonant K+ Lambda photoproduction mechanisms at all production angles.Comment: 22 pages, 16 figure

    Measurement of the Nucleon Structure Function F2 in the Nuclear Medium and Evaluation of its Moments

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    We report on the measurement of inclusive electron scattering off a carbon target performed with CLAS at Jefferson Laboratory. A combination of three different beam energies 1.161, 2.261 and 4.461 GeV allowed us to reach an invariant mass of the final-state hadronic system W~2.4 GeV with four-momentum transfers Q2 ranging from 0.2 to 5 GeV2. These data, together with previous measurements of the inclusive electron scattering off proton and deuteron, which cover a similar continuous two-dimensional region of Q2 and Bjorken variable x, permit the study of nuclear modifications of the nucleon structure. By using these, as well as other world data, we evaluated the F2 structure function and its moments. Using an OPE-based twist expansion, we studied the Q2-evolution of the moments, obtaining a separation of the leading-twist and the total higher-twist terms. The carbon-to-deuteron ratio of the leading-twist contributions to the F2 moments exhibits the well known EMC effect, compatible with that discovered previously in x-space. The total higher-twist term in the carbon nucleus appears, although with large systematic uncertainites, to be smaller with respect to the deuteron case for n<7, suggesting partial parton deconfinement in nuclear matter. We speculate that the spatial extension of the nucleon is changed when it is immersed in the nuclear medium.Comment: 37 pages, 15 figure

    A Bayesian analysis of pentaquark signals from CLAS data

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    We examine the results of two measurements by the CLAS collaboration, one of which claimed evidence for a Θ+\Theta^{+} pentaquark, whilst the other found no such evidence. The unique feature of these two experiments was that they were performed with the same experimental setup. Using a Bayesian analysis we find that the results of the two experiments are in fact compatible with each other, but that the first measurement did not contain sufficient information to determine unambiguously the existence of a Θ+\Theta^{+}. Further, we suggest a means by which the existence of a new candidate particle can be tested in a rigorous manner.Comment: 5 pages, 3 figure

    Observation of the Ξc+\Xi_c^+ Charmed Baryon Decays to Σ+Kπ+\Sigma^+ K^-\pi^+, Σ+Kˉ0\Sigma^+ \bar{K}^{*0}, and ΛKπ+π+\Lambda K^-\pi^+\pi^+

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    We have observed two new decay modes of the charmed baryon Ξc+\Xi_c^+ into Σ+Kπ+\Sigma^+ K^-\pi^+ and Σ+Kˉ0\Sigma^+ \bar{K}^{*0} using data collected with the CLEO II detector. We also present the first measurement of the branching fraction for the previously observed decay mode Ξc+ΛKπ+π+\Xi_c^+\to\Lambda K^-\pi^+\pi^+. The branching fractions for these three modes relative to Ξc+Ξπ+π+\Xi_c^+\to\Xi^-\pi^+\pi^+ are measured to be 1.18±0.26±0.171.18 \pm 0.26 \pm 0.17, 0.92±0.27±0.140.92 \pm 0.27 \pm 0.14, and 0.58±0.16±0.070.58 \pm 0.16 \pm 0.07, respectively.Comment: 12 page uuencoded postscript file, postscript file also available through http://w4.lns.cornell.edu/public/CLN

    First measurement of direct f0(980)f_0(980) photoproduction on the proton

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    We report on the results of the first measurement of exclusive f0(980)f_0(980) meson photoproduction on protons for Eγ=3.03.8E_\gamma=3.0 - 3.8 GeV and t=0.41.0-t = 0.4-1.0 GeV2^2. Data were collected with the CLAS detector at the Thomas Jefferson National Accelerator Facility. The resonance was detected via its decay in the π+π\pi^+ \pi^- channel by performing a partial wave analysis of the reaction γppπ+π\gamma p \to p \pi^+ \pi^-. Clear evidence of the f0(980)f_0(980) meson was found in the interference between PP and SS waves at Mπ+π1M_{\pi^+ \pi^-}\sim 1 GeV. The SS-wave differential cross section integrated in the mass range of the f0(980)f_0(980) was found to be a factor of 50 smaller than the cross section for the ρ\rho meson. This is the first time the f0(980)f_0(980) meson has been measured in a photoproduction experiment
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