Predictors of Severe Acute Respiratory Syndrome Coronavirus 2 Infection Following High-Risk Exposure

BackgroundNon-pharmaceutical interventions (NPIs) are recommended for COVID-19 prevention. However, the effectiveness of NPIs in preventing SARS-CoV-2 transmission remains poorly quantified.MethodsWe conducted a test-negative design case-control study enrolling cases (testing positive for SARS-CoV-2) and controls (testing negative) with molecular SARS-CoV-2 diagnostic test results reported to California Department of Public Health between 24 February-12 November, 2021. We used conditional logistic regression to estimate adjusted odds ratios (aORs) of case status among participants who reported contact with an individual known or suspected to have been infected with SARS-CoV-2 ("high-risk exposure") ≤14 days before testing.Results751 of 1448 cases (52%) and 255 of 1443 controls (18%) reported high-risk exposures ≤14 days before testing. Adjusted odds of case status were 3.02-fold (95% confidence interval: 1.75-5.22) higher when high-risk exposures occurred with household members (vs. other contacts), 2.10-fold (1.05-4.21) higher when exposures occurred indoors (vs. outdoors only), and 2.15-fold (1.27-3.67) higher when exposures lasted ≥3 hours (vs. shorter durations) among unvaccinated and partially-vaccinated individuals; excess risk associated with such exposures was mitigated among fully-vaccinated individuals. Cases were less likely than controls to report mask usage during high-risk exposures (aOR = 0.50 [0.29-0.85]). The adjusted odds of case status was lower for fully-vaccinated (aOR = 0.25 [0.15-0.43]) participants compared to unvaccinated participants. Benefits of mask usage were greatest among unvaccinated and partially-vaccinated participants, and in interactions involving non-household contacts or interactions occurring without physical contact.ConclusionsNPIs reduced the likelihood of SARS-CoV-2 infection following high-risk exposure. Vaccine effectiveness was substantial for partially and fully vaccinated persons

Health Screening and Health Promotion Programs for the Elderly

As the population of elderly people worldwide continues to grow, successful aging has risen to the top of the health policy agenda. The definition of successful aging includes the maintenance of physical and mental function, as well as continued social engagement. Given this definition, maintaining health-related quality of life (HR-QOL) should be a key goal for nutrition and physical activity programs targeted toward the elderly. HR-QOL encompasses physical functioning necessary for unassisted living, as well as broader domains of mental functioning and overall life satisfaction. This review examines the relationship between health parameters and HR-QOL, and assesses the degree to which these relationships are addressed in existing screening and promotion programs. In many cases, nutrition screening and evaluation tools have focused on biomedical measures, such as bodyweight, body fat, or plasma lipids, without taking QOL into account. While HR-QOL has been considered in a few health promotion campaigns, a more balanced perspective on wellness and health among the elderly is needed for the design of effective policies and programs. Successful aging can depend on such factors as race, ethnicity, education, and access to economic and social resources. Intervention programs reviewed include those that address nutritional status, physical activity, and mental health issues among community-dwelling elderly. A comprehensive approach to promoting health in aging would incorporate indicators of wellbeing, and would specifically address nutrition and physical activity issues alongside HR-QOL. Public health policies reviewed here are designed to create an infrastructure to promote healthy aging and offer support to the growing elderly population

Health Screening and Health Promotion Programs for the Elderly

As the population of elderly people worldwide continues to grow, successful aging has risen to the top of the health policy agenda. The definition of successful aging includes the maintenance of physical and mental function, as well as continued social engagement. Given this definition, maintaining health-related quality of life (HR-QOL) should be a key goal for nutrition and physical activity programs targeted toward the elderly. HR-QOL encompasses physical functioning necessary for unassisted living, as well as broader domains of mental functioning and overall life satisfaction. This review examines the relationship between health parameters and HR-QOL, and assesses the degree to which these relationships are addressed in existing screening and promotion programs. In many cases, nutrition screening and evaluation tools have focused on biomedical measures, such as bodyweight, body fat, or plasma lipids, without taking QOL into account. While HR-QOL has been considered in a few health promotion campaigns, a more balanced perspective on wellness and health among the elderly is needed for the design of effective policies and programs. Successful aging can depend on such factors as race, ethnicity, education, and access to economic and social resources. Intervention programs reviewed include those that address nutritional status, physical activity, and mental health issues among community-dwelling elderly. A comprehensive approach to promoting health in aging would incorporate indicators of wellbeing, and would specifically address nutrition and physical activity issues alongside HR-QOL. Public health policies reviewed here are designed to create an infrastructure to promote healthy aging and offer support to the growing elderly population.Diet, Elderly, Ethnic-groups, Exercise, Health-status