80 research outputs found

    Technical Breakthrough Points and Opportunities in Transition Scenarios for Hydrogen as Vehicular Fuel

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    This technical reports is about investigating a generic case of hydrogen production/delivery/dispensing pathway evolution in a large population city, assuming that hydrogen fuel cell electric vehicles (FCEV) will capture a major share of the vehicle market by the year 2050. The range of questions that are considered includes (i) what is the typical succession of hydrogen pathways that minimizes consumer cost? (ii) what are the major factors that will likely influence this sequence

    Asynchronous Programming As A Means To Increase The Productivity Of Smart Home Management Systems

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    This article considers the main problem of modern high-load systems, namely, the productivity of their work. The main purpose of this article is to find an approach to address the issue of high-load systems performance, particularly smart house management systems. These systems have become very popular in our time, the number of their users is growing every year, so the question of their performance is very relevant. In order to achieve this goal, I will consider existing problems and different ways of their solutions. The approach of asynchronous programming is proposed as one of the ways to solve a problem of productivity. It will greatly increase the bandwidth of servers and reduce the response time to customer requests - two common problems that arise when designing high-load systems. The relevance of the proposed solution will be tested experimentally, with the results presented in tabular form

    ЭКСПЕРИМЕНТАЛЬНОЕ ОПРЕДЕЛЕНИЕ ИНТЕНСИВНОСТИ ТЕПЛООБМЕНА ПРИ ВЫНУЖДЕННОЙ КОНВЕКЦИИ ВОЗДУХА ВО ВНУТРЕННИХ КАНАЛАХ ПЛОСКИХ ТРУБ

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    The paper describes an installation and methods of experimental studies concerning heat transfer processes under forced air convection in internal channels of the flat pipes, which allow to take measurements of heat transfer intensity. The paper presents measurements of heat transfer intensity in respect of pipes with separate ribs of small height and pipes with channels, communicating with the help of round holes.Описаны установка и методика экспериментальных исследований процессов теплоотдачи при вынужденной конвекции воздуха во внутренних каналах плоских труб, которые позволяют проводить измерения интенсивности теплообмена. Приведены результаты измерений интенсивности теплообмена для труб с отдельными ребрами малой высоты и труб с каналами, сообщающихся при помощи круглых отверстий

    Обобщение результатов исследований теплообмена между потоком воздуха и оребренной поверхностью, полученной при подрезании ребер со смещением оси

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    The given paper contains an analysis and presents a generalization of experimental results pertaining to heat exchange between an air flow and a surface of a flat pipe when its finning is made with various values of displacement of a tool rotation axis relative to a symmetry axis of a blank.Criterion dependences obtained as result of experimental data generalization provide the possibility to use them for calculation of external heat exchange intensity and losses of pressure in heat exchangers made of aluminum flat fined tubes.Проведен анализ и представлено обобщение результатов экспериментальных исследований теплообмена между потоком воздуха и поверхностью плоской трубы, оребрение которой было выполнено с различными величинами смещения оси вращения инструмента относительно оси симметрии заготовки.Полученные в результате обобщения экспериментальных данных критериальные зависимости дают возможность использовать их при проведении расчетов интенсивности внешнего теплообмена и потерь давления в теплообменниках, изготовленных из плоских оребренных алюминиевых труб

    Малая ГТФаза Rab3B: биологические свойства и возможная роль в канцерогенезе

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    Proteins of the superfamily of small guanosine triphosphate hydrolase (GTPase) perform various functions: from the control of cell proliferation to the regulation of vesicular transport. The superfamily of small GTPase Ras includes more than 150 proteins, devided to 5 major families (Arf, Ran, Rho, Ras and Rab), and plays an important role in carcinogenesis. Compared to the other families, the Rab family was investigated by relatively small number studies, which does not equally reflect their role in malignant transformation processes. In our review  we have focused on both the subfamily Rab3 and its poorly investigated member Rab3B. Recent findings allow to consider Rab3B not only  as a promising diagnostic or prognostic marker for several types of neoplasms, but also is a potential target for antitumor therapy. Our analysis of publicly available transcriptional databases revealed that kidney, lung and liver cancer patients with low Rab3B gene expression demonstrate a better overall five-year survival.Белки суперсемейства малых гуанозинтрифосфат гидролаз (ГТФаз) выполняют различные функции: от контроля клеточной пролиферации до регуляции везикулярного транспорта. Суперсемейство малых ГТФаз Ras включает более 150 белков, 5 основных семейств (Arf, Ran, Rho, Ras и Rab) и играет важную роль в канцерогенезе. По сравнению с остальными семействами малых ГТФаз, белкам семейства Rab посвящено относительно небольшое количество исследований, что не отражает их важную роль в процессах злокачественной трансформации. Помимо рассмотрения семейства Rab в целом, особое внимание в обзоре уделено подсемейству Rab3 и его малоизученному представителю Rab3B. Накопленные к настоящему времени данные позволяют рассматривать Rab3B не только как перспективный диагностический или прогностический маркер при целом ряде новообразований, но и как потенциальную мишень для противоопухолевой терапии. Проведенный нами анализ общедоступных транскриптомных баз данных показал, что пациенты с низкой экспрессией гена Rab3B демонстрируют лучшую общую 5-летнюю выживаемость при раке почки, легкого и печени

    Evaluation of a proposal for reliable low-cost grid power with 100% wind, water, and solar

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    A number of analyses, meta-Analyses, and assessments, including those performed by the Intergovernmental Panel on Climate Change, the National Oceanic and Atmospheric Administration, the National Renewable Energy Laboratory, and the International Energy Agency, have concluded that deployment of a diverse portfolio of clean energy technologies makes a transition to a low-carbon-emission energy system both more feasible and less costly than other pathways. In contrast, Jacobson et al. [Jacobson MZ, Delucchi MA, Cameron MA, Frew BA (2015) Proc Natl Acad Sci USA 112(49):15060-15065] argue that it is feasible to provide low-cost solutions to the grid reliability problem with 100% penetration of WWS [wind, water and solar power] across all energy sectors in the continental United States between 2050 and 2055 , with only electricity and hydrogen as energy carriers. In this paper, we evaluate that study and find significant shortcomings in the analysis. In particular, we point out that this work used invalid modeling tools, contained modeling errors, and made implausible and inadequately supported assumptions. Policy makers should treat with caution any visions of a rapid, reliable, and low-cost transition to entire energy systems that relies almost exclusively on wind, solar, and hydroelectric power

    Planetary Dynamics and Habitable Planet Formation In Binary Star Systems

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    Whether binaries can harbor potentially habitable planets depends on several factors including the physical properties and the orbital characteristics of the binary system. While the former determines the location of the habitable zone (HZ), the latter affects the dynamics of the material from which terrestrial planets are formed (i.e., planetesimals and planetary embryos), and drives the final architecture of the planets assembly. In order for a habitable planet to form in a binary star system, these two factors have to work in harmony. That is, the orbital dynamics of the two stars and their interactions with the planet-forming material have to allow terrestrial planet formation in the habitable zone, and ensure that the orbit of a potentially habitable planet will be stable for long times. We have organized this chapter with the same order in mind. We begin by presenting a general discussion on the motion of planets in binary stars and their stability. We then discuss the stability of terrestrial planets, and the formation of potentially habitable planets in a binary-planetary system.Comment: 56 pages, 29 figures, chapter to appear in the book: Planets in Binary Star Systems (Ed. N. Haghighipour, Springer publishing company
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