Fitspiration on social media: Body-Image and other psychopathological risks among young adults. A narrative review.

Background The use of social media is popular in the health and the beauty industry, with an increasing number of brands using web platforms to promote their products. Among the recently-emerged trends, “fitspiration” (also abbreviated as “fitspo”) has raised health concerns. Evidence suggested that fitspiration contents, although originally conceived to promote a healthier lifestyle, often portray distressful themes that can lead to unhealthy thoughts and behaviours (e.g., body image and eating disturbances, excessive exercising, misuse of supplements). Despite its popularity, the knowledge on this trend is limited and relatively few studies explored its psychological impact on young people below 25-year-old. Methods A narrative literature search was conducted in order to provide an overview of the evidence linking fitspiration trends on social media to mental health disturbances. Results Various factors related to psychopathological risks have been associated with the exposure to fitspiration contents, which we have clustered in the following main topics: (i) exercise addiction and compulsive exercise; (ii) body dissatisfaction and objectification; (iii) appearance-related anxiety and depressive symptoms, self-esteem; (iv) excessive control of eating habits; (v) use of enhancing drugs; (vi) quality of life. Conclusion A wide range of negative psychological effects associated with fitspiration contents on social media were identified. Additional research is required to further elucidate the phenomenon, to determine the extent of the harm for young people, and to develop preventive mental health strategies.Peer reviewedFinal Published versio

Risk factors for acquisition of hepatitis C virus infection: a case series and potential implications for disease surveillance

BACKGROUND: Transmission of hepatitis C vims (HCV) is strongly associated with use of contaminated blood products and injection drugs. Other "non-parental" modes of transmission including sexual activity have been increasingly recognized. We examined risk factors for acquiring HCV in patients who were referred to two tertiary care centers and enrolled in an antiviral therapy protocol. METHODS: Interviews of 148 patients were conducted apart from their physician evaluation using a structured questionnaire covering demographics and risk factors for HCV acquisition. RESULTS: Risk factors (blood products, injection/intranasal drugs, razor blades/ toothbrushes, body/ear piercing, occupational exposure, sexual activity) were identified in 141 (95.3%) of participants; 23 (15.5%) had one (most frequently blood or drug exposure), 41 (27.7%) had two, and 84 (53.4%) had more than two risk factors. No patient reported sexual activity as a sole risk factor. Body piercing accounted for a high number of exposures in women. Men were more likely to have exposure to street drugs but less exposure to blood products than women. Blood product exposure was less common in younger than older HCV patients. CONCLUSION: One and often multiple risk factors could be identified in nearly all HCV-infected patients seen in a referral practice. None named sexual transmission as the sole risk factor. The development of a more complete profile of factors contributing to transmission of HCV infection may assist in clinical and preventive efforts. The recognition of the potential presence of multiple risk factors may have important implications in the approach to HCV surveillance, and particularly the use of hierarchical algorithms in the study of risk factors

Iron reduction before and during interferon therapy of chronic hepatitis C: Results of a multicenter, randomized, controlled trial

Patients with chronic hepatitis C and low serum and hepatic iron stores may have an improved response to interferon (IFN). We tested whether iron reduction before and during IFN therapy would lead to an improved sustained biochemical and virological response compared with IFN alone. Eighty-two previously untreated patients with chronic hepatitis C were randomized to either: group A IFN-Α2b 3 MU 3 times per week for 6 months, or group B iron reduction before and during IFN-Α2b 3 MU 3 times per week for 6 months. Group B patients had lower mean serum alanine transaminase (ALT) levels than group A patients during treatment and follow-up. Group B patients had significantly lower mean hepatitis C virus (HCV)-RNA levels at treatment weeks 4 and 12 ( P < .05). Serum HCV RNA was undetectable at the end of treatment in 15 group B patients compared with 7 group A patients ( P = .03); 7 group B patients and 3 group A patients had persistently undetectable serum HCV RNA 24 weeks after the end of therapy ( P = .20). Paired pre- and posttreatment liver biopsies in 18 group B patients demonstrated significant improvements in 2 of the 3 inflammation scores of the Knodell histological activity index ( P < .05). No changes occurred in the paired biopsies from 15 group A patients. We conclude that iron reduction via therapeutic phlebotomy improves the end-of-treatment virological and histological response to short-term IFN therapy. Additional studies are needed to determine if iron reduction in combination with higher doses or longer duration of IFN may be of benefit.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/34777/1/510310325_ftp.pd