6,137 research outputs found
A bibliography /with abstracts/ on gas-lubricated bearings Interim report
Gas lubricated bearings - annotated bibliograph
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A Study of the Relationship Between Health and Subjective Well-being in Parkinson’s Disease Patients
Objectives: In light of the apparent disconnect between traditional measures of societal well-being such as GDP and reported levels of happiness, governments globally are turning their attention to alternative subjective measures of well-being (SWB) to aid policy decisions. In the context of health, there is therefore growing interest in understanding how measures of health-related quality of life (HRQoL), widely used in health technology appraisal, relates to SWB, and whether SWB could provide a sound basis for resource allocation decisions in health and other sectors in the future. This study investigates the relationship between HRQoL, as measured by EQ-5D, and SWB in Parkinson’s disease (PD) and the extent to which patients’ self-reported health can explain (part of) their SWB.
Methods: A paper questionnaire including EQ-5D, four key SWB questions taken from the Office for National Statistics Integrated Household Survey in England and other demographic details was distributed to people with PD in the UK. Responses were used to estimate multiple regression models explaining SWB using each of the EQ-5D Index (UK weights), EQ-5D dimensions and EQ-VAS and patient socio-demographic characteristics.
Results: 276 questionnaires were distributed and 183 responses received. The EQ-5D Index was a moderate predictor of SWB (adjusted R2 range 0.19-0.38 in OLS models), but EQ-VAS performed better (adjusted R2 range 0.32-0.49).
Combining EQ-VAS and EQ-5D dimensions, especially anxiety/depression and mobility, and household status in some cases, yielded the best-fitting models (adjusted R2 range 0.40-0.52).
Conclusions: The findings imply that EQ-VAS and some dimensions of the EQ-5D, together with key demographic data, could potentially be used to predict SWB, e.g. via mapping. However, further empirical research into the relationship between SWB and EQ-5D longitudinally, and in different disease areas, is required to corroborate these findings, and further standardisation of SWB measures is recommended
The health state preferences and logistical inconsistencies of New Zealanders: a tale of two tariffs
Notwithstanding the proposed use of Cost-Utility Analysis (CUA) to inform health care priority setting in New Zealand, to date there has been no research into New Zealanders’ valuations of health-related quality of life. This paper reports the results of a study of the health state preferences of adult New Zealanders generated from a postal survey to which 1360 people responded (a 50% response rate). The survey employed a self-completed questionnaire in which a selection of health states were described using the EQ-5D health state classification system and respondents’ valuations were sought using a visual analogue scale (VAS). Close attention is paid to the quality of the data, in particular to the ‘logical inconsistencies’ in respondents’ valuations. Regression analysis is used to interpolate values over the 245 possible EQ-5D states. Two tariffs of health state preferences, arising from contrasting treatments of the logical inconsistencies, are reported.New Zealand, EuroQol, EQ-5D
Robust correlators
Radio frequency interference (RFI) already limits the sensitivity of existing
radio telescopes in several frequency bands and may prove to be an even greater
obstacle for future generation instruments to overcome. I aim to create a
structure of radio astronomy correlators which will be statistically stable
(robust) in the presence of interference. A statistical analysis of the mixture
of system noise + signal noise + RFI is proposed here which could be
incorporated into the block diagram of a correlator. Order and rank statistics
are especially useful when calculated in both temporal and frequency domains.
Several new algorithms of robust correlators are proposed and investigated
here. Computer simulations and processing of real data demonstrate the efficacy
of the proposed algorithms
The magnetic reorientation transition in thin ferromagnetic films treated by many-body Green's function theory
This contribution describes the reorientation of the magnetization of thin
ferromagnetic Heisenberg films as function of the temperature and/or an
external field. Working in a rotating frame allows an exact treatment of the
single-ion anisotropy when going to higher-order Green's functions. Terms due
to the exchange interaction are treated by a generalized Tyablikov (RPA)
decoupling.Comment: 9 pages, 2 figure
GemTools: A fast and efficient approach to estimating genetic ancestry
To uncover the genetic basis of complex disease, individuals are often
measured at a large number of genetic variants (usually SNPs) across the
genome. GemTools provides computationally efficient tools for modeling genetic
ancestry based on SNP genotypes. The main algorithm creates an eigenmap based
on genetic similarities, and then clusters subjects based on their map
position. This process is continued iteratively until each cluster is
relatively homogeneous. For genetic association studies, GemTools matches cases
and controls based on genetic similarity.Comment: 5 pages, 1 figur
Accelerator measurement of the energy spectra of neutrons emitted in the interaction of 3-GeV protons with several elements
The application of time of flight techniques for determining the shapes of the energy spectra of neutrons between 20 and 400 MeV is discussed. The neutrons are emitted at 20, 34, and 90 degrees in the bombardment of targets by 3 GeV protons. The targets used are carbon, aluminum, cobalt, and platinum with cylindrical cross section. Targets being bombarded are located in the internal circulating beam of a particle accelerator
Economic evaluation of a community based exercise programme to prevent falls
OBJECTIVE: To assess the incremental costs and cost effectiveness of implementing a home based muscle strengthening and balance retraining programme that reduced falls and injuries in older women. DESIGN: An economic evaluation carried out within a randomised controlled trial with two years of follow up. Participants were individually prescribed an exercise programme (exercise group, n=116) or received usual care and social visits (control group, n=117). SETTING: 17 general practices in Dunedin, New Zealand. PARTICIPANTS: Women aged 80 years and older living in the community and invited by their general practitioner to take part. MAIN OUTCOME MEASURES: Number of falls and injuries related to falls, costs of implementing the intervention, healthcare service costs resulting from falls and total healthcare service costs during the trial. Cost effectiveness was measured as the incremental cost of implementing the exercise programme per fall event prevented. MAIN RESULTS: 27% of total hospital costs during the trial were related to falls. However, there were no significant differences in health service costs between the two groups. Implementing the exercise programme for one and two years respectively cost 265 (1995 New Zealand dollars) per fall prevented, and 426 per fall resulting in a moderate or serious injury prevented. CONCLUSIONS: The costs resulting from falls make up a substantial proportion of the hospital costs for older people. Despite a reduction in falls as a result of this home exercise programme there was no significant reduction in healthcare costs. However, the results reported will provide information on the cost effectiveness of the programme for those making decisions on falls prevention strategies
Integrating visual and tactile information in the perirhinal cortex
By virtue of its widespread afferent projections, perirhinal cortex is thought to bind polymodal information into abstract object-level representations. Consistent with this proposal, deficits in cross-modal integration have been reported after perirhinal lesions in nonhuman primates. It is therefore surprising that imaging studies of humans have not observed perirhinal activation during visual–tactile object matching. Critically, however, these studies did not differentiate between congruent and incongruent trials. This is important because successful integration can only occur when polymodal information indicates a single object (congruent) rather than different objects (incongruent). We scanned neurologically intact individuals using functional magnetic resonance imaging (fMRI) while they matched shapes. We found higher perirhinal activation bilaterally for cross-modal (visual–tactile) than unimodal (visual–visual or tactile–tactile) matching, but only when visual and tactile attributes were congruent. Our results demonstrate that the human perirhinal cortex is involved in cross-modal, visual–tactile, integration and, thus, indicate a functional homology between human and monkey perirhinal cortices
Age-Related Needs of Community College Students
The literature of adult education commonly suggests that older learners have a distinct set of needs and a unique mode of learning that ought to be honoured by educational institutions; other observers note that education is a process whose generic elements are not age-related. Capilano College, with a strong com- mitment to mature learners as part of its community orientation, surveyed its student population by age grouping to determine the extent to which significant, substantive differences in the self-perceived needs of different age groupings were evident. The survey revealed that, although there were several distinguishing characteristics between students below and above age 25, younger and older students share a large common set of needs; older students seem to have a greater number of needs and appear to feel them more acutely.Généralement, la documentation sur l'éducation permanente semble indiquer que les étudiants adultes éprouvent des besoins distincts et possèdent un mode d'apprentissage qui leur est particulier et dont les institutions d'enseignement devraient tenir compte. D'autres observateurs remarquent que l'instruction est un processus dont les éléments génériques n'ont rien à voir avec le facteur-âge. Le Collège Capilano dans la poursuite de son engagement envers les étudiants adultes et envers la communauté qu'il dessert a fait une étude de sa population étudiante par groupe d'âge afin de déterminer dans quelle mesure il y avait évidence de différences significatives dans les besoins perçus par les différents groupes d'âges. L'étude a révélé que malgré certaines caractéristiques particu-lières aux étudiants de moins et de plus de 25 ans, la population étudiante en général éprouve des besoins communs. Les étudiants adultes paraissent éprouver un plus grand nombre de besoins et semblent les ressentir plus vivement
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