Vanishing Minors in the Neutrino Mass Matrix from Abelian Gauge Symmetries

Augmenting the Standard Model by three right-handed neutrinos allows for an anomaly-free gauge group extension G_max = U(1)_(B-L) x U(1)_(L_e-L_mu) x U(1)_(L_mu-L_tau). While simple U(1) subgroups of G_max have already been discussed in the context of approximate flavor symmetries, we show how two-zero textures in the right-handed neutrino Majorana mass matrix can be enforced by the flavor symmetry, which is spontaneously broken very economically by singlet scalars. These zeros lead to two vanishing minors in the low-energy neutrino mass matrix after the seesaw mechanism. This study may provide a new testing ground for a zero-texture approach: the different classes of two-zero textures with almost identical neutrino oscillation phenomenology can in principle be distinguished by their different Z' interactions at colliders.Comment: 12 pages; Extended and clarified discussion; comments on finetuning in the textures; matches published versio

Non-standard interactions versus non-unitary lepton flavor mixing at a neutrino factory

The impact of heavy mediators on neutrino oscillations is typically described by non-standard four-fermion interactions (NSIs) or non-unitarity (NU). We focus on leptonic dimension-six effective operators which do not produce charged lepton flavor violation. These operators lead to particular correlations among neutrino production, propagation, and detection non-standard effects. We point out that these NSIs and NU phenomenologically lead, in fact, to very similar effects for a neutrino factory, for completely different fundamental reasons. We discuss how the parameters and probabilities are related in this case, and compare the sensitivities. We demonstrate that the NSIs and NU can, in principle, be distinguished for large enough effects at the example of non-standard effects in the $\mu$-$\tau$-sector, which basically corresponds to differentiating between scalars and fermions as heavy mediators as leading order effect. However, we find that a near detector at superbeams could provide very synergistic information, since the correlation between source and matter NSIs is broken for hadronic neutrino production, while NU is a fundamental effect present at any experiment.Comment: 32 pages, 5 figures. Final version published in JHEP. v3: Typo in Eq. (27) correcte

A study on the financial feasibility of compliant ship recycling yards in Bangladesh

\ua9 2023 ANAME Publication.Ship recycling is one of the most promising industries for Bangladesh. A significant amount of local steel demand is fulfilled by scrap metals from ship recycling yards. Bangladesh has been maintaining a competitive position in the ship recycling sector along with China, India, and Pakistan. But, in the absence of substantial workplace safety and infrastructure development and for not following international regulations, Bangladesh may lose its market share to other countries in this sector. This paper presents a financial analysis to establish compliant ship recycling facilities that will fulfill the Hong Kong Convention (HKC) requirements. This analysis has considered all the facilities of a compliant ship-recycling yard, including impermeable floors, mechanized systems, oily water separators, firefighting systems, and other special features. The worthiness, scalability, and sustainability of investing in the development of compliant ship recycling facilities have been assessed from Bangladesh’s perspective and the benefits over the conventional ones have been discussed. Also, the challenges for ship recyclers and their prevalent perspective toward establishing compliant ship recycling facilities have been depicted. Lastly, recommendations have been suggested to assist the ship recyclers in Bangladesh by encouraging them to invest and enable HKC-compliant ship recycling to harness long-term economic rewards

To Evaluate The Effectiveness Of Del Nido Cardioplegia In Adult Cardiac Surgery At A Tertiary Care Centre

el Nido cardioplegia has emerged as a promising myocardial protector in adult open heart surgeries after it\u27s initial success in Paediatric open heart surgeries, specially in immature myocardiums. To conclude, del Nido as an effective cardioplegic agent among the adult open heart surgeries one must compare it\u27s advantages and disadvantages with other cardioplegic agents. Methodology This is a retrospective study where about 200 patients were studied who were adults with first time CABG, Valve Surgery, interventions for Aneurysms etc requiring CPB. After obtaining the institutional ethical committee approval the study was conducted. Primary outcomes were assessed for spontaneous cardiac rhythm, requirement of Shocks( defibrillatory) Troponin levels compared with baseline, after 1,2 hours after the CPB (pump off), ventilatory duration, length of ICU stay, requirement of Insulin, glycaemic indices, overall hospital stay, mortality etc several of these factors were  studied. Results Pre-operative criteria were almost similar between groups including age, society of thoracic surgeons risk score, for CABG and valve procedures There was no significant difference on CPB time (98 vs 104 minutes) and cross clamp time(68 vs 79.8 minutes: p=0.019). The Del Nido group showed higher return to spontaneous rhythm(97. 8%  vs 81.7% p= 0. 022 and fewer patients required inotropic support (65.1% vs84. 32%) but did not reach the statistical significance. Conclusions From this study it may be inferred that del Nido cardioplegia may be used safely for adult cardiac surgeries with streamlined surgical workflow. Troponin should be checked baseline and at time bound manner to prove the Superiority of the cardioplegia

Determinan Keputusan Petani Dalam Pengambilan Kredit Sektor Pertanian Kecamatan Lamaknen Kabupaten Belu Provinsi Nusa Tenggara Timur

Sektor pertanian merupakan salah satu sektor utama di Kecamatan Lamaknen Kabupaten Belu Provinsi Nusa Tenggara Timur dengan potensi sumber daya alamnya. Meski demikian, pengembangan sektor pertanian memiliki keterbatasan–keterbatasan dalam meningkatkan produksi yang salah satunya disebabkan oleh kendala modal, baik internal maupun eksternal. Salah satu sumber modal eksternal yang mampu mendukung peningkatan hasil produksi pertanian adalah kredit. Ironisnya, data kajian ekonomi dan keuangan regional dari Bank Indonesia Provinsi Nusa Tenggara Timur tahun 2016-2018 menunjukkan bahwa tren penyaluran kredit pertanian cenderung mengalami penurunan. Penelitian ini bertujuan untuk menganalisis pengaruh faktor determinan keputusan petani dalam pengambilan kredit sektor pertanian di Kecamatan Lamaknen Kabupaten Belu Provinsi Nusa Tenggara Timur. Determinan di sini meliputi Luas kepemilikan lahan (X1), Umur (X2), Pendidikan (X3), Pendapatan (X4), Pengalaman kredit (X5), dan Layanan penyuluhan (X6) yang dinyatakan sebagai variabel independen. Adapun variabel dependennya adalah Keputusan pengambilan kredit (Y). Metode yang digunakan dalam penelitian ini adalah metode kuantitatif. Populasi yang ditentukan adalah seluruh petani di Kecamatan Lamaknen yang terdiri dari 10 unit desa. Selanjutnya, sampel yang diteliti yaitu seluruh petani di Desa Makir. Teknik pengambilan sampel yang digunakan adalah probabillity sampling. Data primer diperoleh dengan menggunakan kuesioner dan kemudian diuji dengan metode analisis Regresi Logistik pada program SPSS 21. Dalam pengambilan keputusan hasil analisis, penelitian ini menggunakan nilai taraf nyata () sebesar 0,05 atau 5%. Berdasarkan hasil penelitian, diketahui bahwa luas kepemilikan lahan (X1) memiliki nilai signifikansi (p-value) 0,04, Umur (X2) memiliki nilai signifikansi 0,01, Pendidikan (X3) memiliki nilai signifikansi 0,41, Pendapatan (X4) memiliki nilai signifikansi 0,02, Pengalaman kredit (X5) memiliki nilai signifikansi 0,04, dan Layanan penyuluhan (X6) memiliki nilai signifikansi 0,01. Sehingga, dapat dinyatakan bahwa Luas kepemilikan lahan, Umur, Pendapatan, Pengalaman kredit, dan Layanan penyuluhan memiliki pengaruh yang signifikan (p-value 0,05). Nilai koefisien determinasi yang diperoleh adalah sebesar 0,648, sehingga dapat dinyatakan bahwa besar pengaruh variabel independen terhadap keputusan pengambilan kredit petani adalah sebesar 64,8%. Adapun sisanya yaitu 35,2% mewakili pengaruh dari variabel lain yang tidak dikaji dalam penelitian ini. Selanjutnya, Nilai Wald tertinggi terdapat pada variabel Pengalaman kredit (X5), yakni sebesar 6,684, yang kemudian disusul oleh variabel Umur (X2) dengan nilai 6,434. Dengan demikian, maka dapat dinyatakan bahwa variabel yang berpengaruh dominan terhadap keputusan pengambilan kredit sektor pertanian di Kecamatan Lamaknen Kabupaten Belu Provinsi Nusa Tenggara Timur adalah pengalaman kredit petani itu sendiri

Rif1 S-acylation mediates DNA double-strand break repair at the inner nuclear membrane

Rif1 is involved in telomere homeostasis, DNA replication timing, and DNA double-strand break (DSB) repair pathway choice from yeast to human. The molecular mechanisms that enable Rif1 to fulfill its diverse roles remain to be determined. Here, we demonstrate that Rif1 is S-acylated within its conserved N-terminal domain at cysteine residues C466 and C473 by the DHHC family palmitoyl acyltransferase Pfa4. Rif1 S-acylation facilitates the accumulation of Rif1 at DSBs, the attenuation of DNA end-resection, and DSB repair by non-homologous end-joining (NHEJ). These findings identify S-acylation as a posttranslational modification regulating DNA repair. S-acylated Rif1 mounts a localized DNA-damage response proximal to the inner nuclear membrane, revealing a mechanism of compartmentalized DSB repair pathway choice by sequestration of a fatty acylated repair factor at the inner nuclear membrane

Pengaruh Guncangan Produksi Industri Dan Tingkat Pengangguran Regional Terhadap Integrasi Pasar Modal Kawasan Uni Eropa Saat Terjadinya Pandemi Covid-19

Banyak penelitian yang membahas dari keuntungan terdapatnya Pasar Tunggal Uni Eropa yang hanya terfokus pada kebebasan perdagangan. Dari perspektif manajemen portofolio, penelitian ini menggunakan metode Vector Autoregressive model untuk mengetahui bagaimana faktor variabel makroekonomi, tingkat pengangguran dan indeks produksi industri, dengan cakupan regional ( EU-27 ) dapat mempengaruhi pergerakan dari return indeks saham negara-negara yang tergabung dalam Uni Eropa khususnya keempat negara dengan perekonomian terbesar yaitu Jerman, Prancis, Italia, dan Spanyol. Penelitian ini juga ingin mengetahui bagaimana respon dari nilai return indeks saham negara-negara Uni Eropa terhadap penambahan jumlah kasus COVID-19 di kawasan Uni Eropa. Hasil penelitian ini menunjukkan bahwa nilai Indeks Produksi Industri Regional, Tingkat Pengangguran Regional, dan Jumlah Kasus COVID-19 Regional Kawasan Uni Eropa secara signifikan mempengaruhi pergerakan return saham dari keempat negara dengan perekonomian terbesar di Kawasan Uni Erop

Glial Heterotopia of the orbit: A rare presentation

<p>Abstract</p> <p>Background</p> <p>Glial heterotopias are rare, benign, congenital, midline, non-teratomatous extracranial glial tissue. They may masquerade as encephalocoele or dermoid cyst and mostly present in nose. Herein, we present an unusual case of glial heterotopia of the orbit with unilateral blindness.</p> <p>Case presentation</p> <p>A 6 year-old-boy presented with a progressive painless mass over the nose and medial aspect of the left eye noticed since birth. On examination, the globe was displaced laterally by a firm, regular, mobile, non-pulsatile and non-tender medial mass. The affected eye had profound loss of vision. Computed tomography scan showed a large hypodense mass in the extraconal space with no intracranial connectivity and bony erosion. The child underwent total surgical excision of the mass and histopathological examination confirmed glial heterotopia of the orbit.</p> <p>Conclusion</p> <p>Though the incidence of this condition is rare, the need of appropriate diagnosis and management of such mass to prevent the visual and cosmetic deterioration is warranted. To our knowledge this is the first reported case of Glial heterotopia of orbit causing unilateral blindness.</p

Approaches in biotechnological applications of natural polymers

Natural polymers, such as gums and mucilage, are biocompatible, cheap, easily available and non-toxic materials of native origin. These polymers are increasingly preferred over synthetic materials for industrial applications due to their intrinsic properties, as well as they are considered alternative sources of raw materials since they present characteristics of sustainability, biodegradability and biosafety. As definition, gums and mucilages are polysaccharides or complex carbohydrates consisting of one or more monosaccharides or their derivatives linked in bewildering variety of linkages and structures. Natural gums are considered polysaccharides naturally occurring in varieties of plant seeds and exudates, tree or shrub exudates, seaweed extracts, fungi, bacteria, and animal sources. Water-soluble gums, also known as hydrocolloids, are considered exudates and are pathological products; therefore, they do not form a part of cell wall. On the other hand, mucilages are part of cell and physiological products. It is important to highlight that gums represent the largest amounts of polymer materials derived from plants. Gums have enormously large and broad applications in both food and non-food industries, being commonly used as thickening, binding, emulsifying, suspending, stabilizing agents and matrices for drug release in pharmaceutical and cosmetic industries. In the food industry, their gelling properties and the ability to mold edible films and coatings are extensively studied. The use of gums depends on the intrinsic properties that they provide, often at costs below those of synthetic polymers. For upgrading the value of gums, they are being processed into various forms, including the most recent nanomaterials, for various biotechnological applications. Thus, the main natural polymers including galactomannans, cellulose, chitin, agar, carrageenan, alginate, cashew gum, pectin and starch, in addition to the current researches about them are reviewed in this article.. }To the Conselho Nacional de Desenvolvimento Cientfíico e Tecnológico (CNPq) for fellowships (LCBBC and MGCC) and the Coordenação de Aperfeiçoamento de Pessoal de Nvíel Superior (CAPES) (PBSA). This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit, the Project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462) and COMPETE 2020 (POCI-01-0145-FEDER-006684) (JAT)

Analisis Pengaruh Kedatangan Wisatawan Mancanegara Berdasarkan Daerah Asal Terhadap Pertumbuhan Ekonomi Di Indonesia

Pengaruh kedatangan wisatawan mancanenegara berdasarkan daerah asal terhadap pertumbuhan ekonomi dianalisis pada penelitian ini, dengan menggunakan data PDB sebagai proxy pertumbuhan ekonomi, jumlah kunjungan wisatawan, Indeks Harga Konsumen, dan Kurs periode triwulanan tahun 2007 – 2016. Penelitian ini menggunakan data sekunder dengan metode regresi Error Correction Model (ECM) dengan perhitungan jangka pendek dan jangka panjang. Hasil penelitian menunjukkan bahwa variabel Jumlah Kunjungan Wisatawan berpengaruh terhadap PDB pada kontinen Asia, Europe, Middle East, dan Oceania sedangkan pada jangka panjang pada seluruh kontinen kecuali America. Variabel kurs dalam jangka pendek berpengaruh negatif terhadap PDB pada Kontinen Amerika dan Middle East , sedangkan pada jangka panjang variabel kurs berpengaruh positif terhadap PDB pada kontinen Asean dan Europe. Variabel IHK hanya berpengaruh positif terhadap PDB dalam jangka panjang pada seluruh kontinen kecuali America. Sehingga dapat disimpulkan bahwa ternyata tidak semua kontinen memberikan dampak positif terhadap PDB salah satunya yaitu kontinen America, sehingga dalam rangka upaya optimasi dan peningkatan pertumbuhan ekonomi disini perlu ditekankan bahwa biaya untuk pengembangan sektor pariwisata dengan sasaran wisatawan kontinen America sebaiknya bisa dialokasikan lebih proporsional atau dialihkan ke kontinen Asia, Asean, Oceania, Europe dan Middle East