Prediction of Strap Joint Design Margin in After Treatment System

The automotive vehicle has an exhaust system, also known as the after treatment System. It consists of different components such as Diesel Oxidation catalysts (DOC), Diesel Particulate Filters (DPF), Selective Catalytic Reduction Systems (SCR), etc. These components are mounted in the chassis with the help of strap joints. The strap joints provide flexible and serviceable connections between ATS bodies and chassis. The strap joint assembly consists of a T bolt, trunnion, and nut with strap. As the nut tightened, the tension induced in the strap, which results in clamping the body. If the tension in the strap is not sufficient, it may cause the failure of the joint. The failure can be yielding of material, slipping, and separation of the body. The strap joint should be designed so that these kinds of failures can be avoided. This paper presents the work on the calculation of the design margin using analytical and FEA methods. The failure modes addressed in this paper are yielding of the strap joint due to applied preload on the T bolt, slipping, and separation of the ATS body from the strap due to the application of dynamic loads such as acceleration G loads in multiple directions. The acceleration load is calculated from the PSD profile. For calculating design margins from the FEA method, nonlinear analysis is performed, followed by PSD analysis to estimate the bracket reaction forces. These reaction forces are used to calculate slip and separation margins. The tests were performed under similar conditions on a shaker table, and the results from both analytical and FEA methods were correlated with test observations to validate the proposed method of calculation of strap join design margin.Published By: Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP) © Copyright: All rights reserved

FORMULATION AND EVALUATION OF MELOXICAM MICROSPHERES FOR COLON TARGETED DRUG DELIVERY

Objectives: The objective of this research was to organize and evaluate colon specific microspheres of the meloxicam for the treatment of colorectal cancer. Methods: Sodium alginate microspheres were prepared by ionotropic gelation method using different ratios of meloxicam and sodium alginate (1:1, 1:2, and 1:3). Eudragit-coating of meloxicam, sodium alginate microspheres was performed by coacervation phase separation technique. Results: The microspheres were characterized by shape, particle size, size distribution, incorporation efficiency, in vitro drug release studies and stability studies. The outer surfaces of the core and coated microspheres, which were spherical in shape, were rough and smooth, respectively. The size of the core microspheres ranged from 20 to 52 μm, and therefore the size of the coated microspheres ranged from 107 to 178 μm. The core microspheres sustained the discharge for 10 h during a pH progression medium mimicking the condition of gastrointestinal tract. The release studies of coated microspheres were performed during a similar dissolution medium as mentioned above. In acidic medium the discharge rate was much slower, however the drug was released quickly at pH 7.4 and their release was sustained up to 24 h. Conclusions: It’s concluded from this investigation that Eudragit-coated sodium alginate microspheres are promising controlled release carriers for colon-targeted delivery of meloxicam

(R2028) A Brief Note on Space Time Fractional Order Thermoelastic Response in a Layer

In this study, a one-dimensional layer of a solid is used to investigate the exact analytical solution of the heat conduction equation with space-time fractional order derivatives and to analyze its associated thermoelastic response using a quasi-static approach. The assumed thermoelastic problem was subjected to certain initial and boundary conditions at the initial and final ends of the layer. The memory effects and long-range interaction were discussed with the help of the Caputo-type fractional-order derivative and finite Riesz fractional derivative. Laplace transform and Fourier transform techniques for spatial coordinates were used to investigate the solution of the temperature distribution and stress functions. Numerical investigations are also shown graphically for non-dimensional temperature and stress for different space and time fractional derivative values, respectively. In addition, some applicable limiting cases are discussed for standard equations, such as wave equation, Laplace equation, and diffusion equation

Internet Of Things Based Nashik Smart City

IoT (Internet of Things) is an advanced automation and analytics system which exploits networking, sensing, big data, and artificial intelligence technology to deliver complete systems for a product or service. These systems allow greater transparency, control, and performance when applied to any industry or system. IoT systems have applications across industries through their unique flexibility and ability to be suitable in any environment. They enhance data collection, automation, operations, and much more through smart devices and powerful enabling technology. IoT is a technical base behind developing smart city and it acts as a building blocks of the same. IoT helps in improving the quality of life of citizens and transforming cities with the help technological solutions

Quantum noise limited microwave amplification using a graphene Josephson junction

Josephson junctions (JJ) and their tunable properties, including their nonlinearities, form the core of superconducting circuit quantum electrodynamics (cQED). In quantum circuits, low-noise amplification of feeble microwave signals is essential and the Josephson parametric amplifiers (JPA) are the widely used devices. The existing JPAs are based on Al-AlOx-Al tunnel junctions realized in a superconducting quantum interference device geometry, where magnetic flux is the knob for tuning the frequency. Recent experimental realizations of 2D van der Waals JJs provide an opportunity to implement various cQED devices with the added advantage of tuning the junction properties and the operating point using a gate potential. While other components of a possible 2D van der Waals cQED architecture have been demonstrated -- quantum noise limited amplifier, an essential component, has not been realized. Here we implement a quantum noise limited JPA, using a graphene JJ, that has linear resonance gate tunability of 3.5 GHz. We report 24 dB amplification with 10 MHz bandwidth and -130 dBm saturation power; performance on par with the best single-junction JPAs. Importantly, our gate tunable JPA works in the quantum-limited noise regime which makes it an attractive option for highly sensitive signal processing. Our work has implications for novel bolometers -- the low heat capacity of graphene together with JJ nonlinearity can result in an extremely sensitive microwave bolometer embedded inside a quantum noise-limited amplifier. In general, our work will open up exploration of scalable device architecture of 2D van der Waals materials by integrating a sensor with the quantum amplifier.Comment: 15 pages, 4 figures, and supplementary informatio

Review Paper on Design and Fabrication of Automatic Dishwasher

Dishwashing is an activity which is to be performed every day, repeatedly. Automation available in these machines is so, complex and energy consuming. To save the power it is essential to use semi-automatic dishwasher. Available dishwasher in market is too big in size, high in cost and more energy consuming. From many years the research and automation is done in this machine, but still it is hard to invent such machine that will be used in day today life

Effects of biofertilizer containing N-fixer, P and K solubilizers and AM fungi on maize growth: A greenhouse trial.

An in vitro study was undertaken to evaluate the compatibility of indigenous plant growth promoting rhizobacteria (PGPR) with commonly used inorganic and organic sources of fertilizers in tea plantations. The nitrogenous, phosphatic and potash fertilizers used for this study were urea, rock phosphate and muriate of potash, respectively. The organic sources of fertilizers neem cake, composted coir pith and vermicompost were also used. PGPRs such as nitrogen fixer; Azospirillum lipoferum, Phosphate Solubilizing Bacteria (PSB); Pseudomonas putida, Potassium Solubilizing Bacteria (KSB); Burkholderia cepacia and Pseudomonas putida were used for compatibility study. Results were indicated that PGPRs preferred the coir pith and they proved their higher colony establishment in the formulation except Azospirillum spp. that preferred vermicompost for their establishment. The optimum dose of neem cake powder

Optimisation and In Vivo Evaluation of Pectin Based Drug Delivery System Containing Curcumin for Colon

The higher incidences of side effects of existing drugs have shifted researchers and clinicians to explore the dietary phytoconstituents for its therapeutic potentials. The present study is based on compression coated curcumin tablet for the colon. Curcumin has anti-inflammatory and antioxidant properties. Curcumin presents a bioavailability problem due to poor solubility. An inclusion complex was formed with hydroxypropyl-β-cyclodextrin to enhance the solubility. In this study, the core tablet of curcumin inclusion complex was compressed between the layers of polymer blend of pectin and Eudragit S100. The 32 full factorial design was utilised for optimization of the formulation. The polymer ratio (X1) and coat thickness (X2) presented significant effects on the selected responses, i.e., percent drug release after 4 hours (Y240) and difference in percent drug release between 4th and 6th hour (Ydiff) in presence of pectinase enzyme. The results revealed that higher coat weight (600 mg) and higher level of pectin ratio (70% w/w) protected the curcumin tablet till ascending colon. The in vivo studies by roentgenography method using human volunteers supported these observations. Hence, it can be concluded that the combination of pectin and Eudrgit S100 makes the system biodegradable and pH dependent for targeting the drug to the colon

COMPARATIVE ANALYSIS OF SHELL AND TUBE TYPE HEAT EXCHANGER WITH EFFECT OF HELICAL BAFFLES AND NANO FLUID: A REVIEW

In shell and tube type heat exchanger, the thermal performance and pressure drop are dependent on the type of fluid flow and type of baffles used in it.Inorder to improve the efficacy of heat exchangers, Nano fluidsare recently employed as coolants in them.Regarding unique characteristics of Nano fluids, research studies in this area have witnessed a remarkablegrowth.This paper presents the simulations carried out on different baffle i.e. helical baffles and different type of fluid i.e. Nano fluid and water. This shows the effect of baffles on heattransfer of fluid in shell and tube heat exchanger. Single segmental baffles show the formation of dead zones where heat transfer cannot do properly. Double segmental baffles reduce the vibrational damage to system as compared to single segmental baffles.The use of helical baffles can decrease in pressure drop by the elimination of dead zones. The less dead zones result in high heat transfer. The helical baffles can create the turbulence flow, which increase heat transfer rate, which increases the overallefficiency of the system.In this paper we will comparatively study of shell and tube type heat exchanger with Nano fluid and water on different mass flow rates