488 research outputs found
A coproduct structure on the formal affine Demazure algebra
In the present paper we generalize the coproduct structure on nil Hecke rings
introduced and studied by Kostant-Kumar to the context of an arbitrary
algebraic oriented cohomology theory and its associated formal group law. We
then construct an algebraic model of the T-equivariant oriented cohomology of
the variety of complete flags.Comment: 28 pages; minor revision of the previous versio
Coloured peak algebras and Hopf algebras
For a finite abelian group, we study the properties of general
equivalence relations on G_n=G^n\rtimes \SG_n, the wreath product of with
the symmetric group \SG_n, also known as the -coloured symmetric group. We
show that under certain conditions, some equivalence relations give rise to
subalgebras of \k G_n as well as graded connected Hopf subalgebras of
\bigoplus_{n\ge o} \k G_n. In particular we construct a -coloured peak
subalgebra of the Mantaci-Reutenauer algebra (or -coloured descent algebra).
We show that the direct sum of the -coloured peak algebras is a Hopf
algebra. We also have similar results for a -colouring of the Loday-Ronco
Hopf algebras of planar binary trees. For many of the equivalence relations
under study, we obtain a functor from the category of finite abelian groups to
the category of graded connected Hopf algebras. We end our investigation by
describing a Hopf endomorphism of the -coloured descent Hopf algebra whose
image is the -coloured peak Hopf algebra. We outline a theory of
combinatorial -coloured Hopf algebra for which the -coloured
quasi-symmetric Hopf algebra and the graded dual to the -coloured peak Hopf
algebra are central objects.Comment: 26 pages latex2
The nil Hecke ring and singularity of Schubert varieties
We give a criterion for smoothness of a point in any Schubert variety in any
G/B in terms of the nil Hecke ring.Comment: AMSTE
GALEX J201337.6+092801: The lowest gravity subdwarf B pulsator
We present the recent discovery of a new subdwarf B variable (sdBV), with an
exceptionally low surface gravity. Our spectroscopy of J20136+0928 places it at
Teff = 32100 +/- 500, log(g) = 5.15 +/- 0.10, and log(He/H) = -2.8 +/- 0.1.
With a magnitude of B = 12.0, it is the second brightest V361 Hya star ever
found. Photometry from three different observatories reveals a temporal
spectrum with eleven clearly detected periods in the range 376 to 566 s, and at
least five more close to our detection limit. These periods are unusually long
for the V361 Hya class of short-period sdBV pulsators, but not unreasonable for
p- and g-modes close to the radial fundamental, given its low surface gravity.
Of the ~50 short period sdB pulsators known to date, only a single one has been
found to have comparable spectroscopic parameters to J20136+0928. This is the
enigmatic high-amplitude pulsator V338 Ser, and we conclude that J20136+0928 is
the second example of this rare subclass of sdB pulsators located well above
the canonical extreme horizontal branch in the HR diagram.Comment: 5 pages, accepted for publication in ApJ Letter
The Kazhdan-Lusztig conjecture for finite W-algebras
We study the representation theory of finite W-algebras. After introducing
parabolic subalgebras to describe the structure of W-algebras, we define the
Verma modules and give a conjecture for the Kac determinant. This allows us to
find the completely degenerate representations of the finite W-algebras. To
extract the irreducible representations we analyse the structure of singular
and subsingular vectors, and find that for W-algebras, in general the maximal
submodule of a Verma module is not generated by singular vectors only.
Surprisingly, the role of the (sub)singular vectors can be encapsulated in
terms of a `dual' analogue of the Kazhdan-Lusztig theorem for simple Lie
algebras. These involve dual relative Kazhdan-Lusztig polynomials. We support
our conjectures with some examples, and briefly discuss applications and the
generalisation to infinite W-algebras.Comment: 11 page
Quantum Pieri rules for isotropic Grassmannians
We study the three point genus zero Gromov-Witten invariants on the
Grassmannians which parametrize non-maximal isotropic subspaces in a vector
space equipped with a nondegenerate symmetric or skew-symmetric form. We
establish Pieri rules for the classical cohomology and the small quantum
cohomology ring of these varieties, which give a combinatorial formula for the
product of any Schubert class with certain special Schubert classes. We also
give presentations of these rings, with integer coefficients, in terms of
special Schubert class generators and relations.Comment: 59 pages, LaTeX, 6 figure
Super duality and irreducible characters of ortho-symplectic Lie superalgebras
We formulate and establish a super duality which connects parabolic
categories between the ortho-symplectic Lie superalgebras and classical Lie
algebras of types. This provides a complete and conceptual solution of
the irreducible character problem for the ortho-symplectic Lie superalgebras in
a parabolic category , which includes all finite-dimensional irreducible
modules, in terms of classical Kazhdan-Lusztig polynomials.Comment: 30 pages, Section 5 rewritten and shortene
Induction of sustained clinical remission in early axial spondyloarthritis following certolizumab pegol treatment: 48-week outcomes from C-OPTIMISE
INTRODUCTION: Achievement of remission is a key treatment goal for patients with axial spondyloarthritis (axSpA). C-OPTIMISE assessed achievement of sustained clinical remission in patients with axSpA, including radiographic (r) and non-radiographic (nr) axSpA, during certolizumab pegol (CZP) treatment, and subsequent maintenance of remission following CZP dose continuation, dose reduction or withdrawal. Here, we report outcomes from the first 48 weeks (induction period) of C-OPTIMISE, during which patients received open-label CZP. METHODS: C-OPTIMISE (NCT02505542) was a two-part, multicenter, phase 3b study in adult patients with early axSpA (r-/nr-axSpA), including a 48-week open-label induction period followed by a 48-week maintenance period. Patients with active adult-onset axSpA, < 5 years' symptom duration, and fulfilling Assessment of SpondyloArthritis international Society classification criteria, were included. During the induction period, patients received a loading dose of CZP 400 mg at weeks 0, 2, and 4, followed by CZP 200 mg every 2 weeks (Q2W) up to week 48. The main outcome of the 48-week induction period was the achievement of sustained clinical remission (defined as an Ankylosing Spondylitis Disease Activity Score [ASDAS] < 1.3 at week 32 and < 2.1 at week 36 [or vice versa], and < 1.3 at week 48). RESULTS: In total, 736 patients (407 with r-axSpA, 329 with nr-axSpA) were enrolled into the study. At week 48, 43.9% (323/736) of patients achieved sustained remission, including 42.8% (174/407) of patients with r-axSpA and 45.3% (149/329) with nr-axSpA. Patients also demonstrated substantial improvements in axSpA symptoms, MRI outcomes and quality of life measures. Adverse events occurred in 67.9% (500/736) of patients, of which 6.0% (44/736) were serious. CONCLUSIONS: Over 40% of patients with early axSpA achieved sustained remission during 48 weeks of open-label CZP treatment. Additionally, patients across the axSpA spectrum demonstrated substantial improvements in imaging outcomes and quality of life following treatment. No new safety signals were identified. TRIAL REGISTRATION: NCT02505542
Standard Monomial Theory for desingularized Richardson varieties in the flag variety GL(n)/B
We consider a desingularization Gamma of a Richardson variety X_w^v=X_w \cap
X^v in the flag variety Fl(n)=GL(n)/B, obtained as a fibre of a projection from
a certain Bott-Samelson variety Z. We then construct a basis of the homogeneous
coordinate ring of Gamma inside Z, indexed by combinatorial objects which we
call w_0-standard tableaux
HPV Genotypes distribution in Indian women with and without cervical carcinoma: Implication for HPV vaccination program in Odisha, Eastern India
- …