XMM-Newton observations of the supernova remnant IC443: I. soft X-ray emission from shocked interstellar medium

The shocked interstellar medium around IC443 produces strong X-ray emission in the soft energy band (E<1.5 keV). We present an analysis of such emission as observed with the EPIC MOS cameras on board the XMM-Newotn observatory, with the purpose to find clear signatures of the interactions with the interstellar medium (ISM) in the X-ray band, which may complement results obtained in other wavelenghts. We found that the giant molecular cloud mapped in CO emission is located in the foreground and gives an evident signature in the absorption of X-rays. This cloud may have a torus shape and the part of torus interacting with the IC443 shock gives rise to 2MASS-K emission in the southeast. The measured density of emitting X-ray shocked plasma increases toward the northeastern limb, where the remnant is interacting with an atomic cloud. We found an excellent correlation between emission in the 0.3-0.5 keV band and bright optical/radio filament on large spatial scales. The partial shell structure seen in this band therefore traces the encounter with the atomic cloud.Comment: 10 pages, 10 figures, accepted for publication in ApJ (20 September 2006, v649). For hi-res figures, see http://www.astropa.unipa.it/Library/OAPA_preprints/ic443ele1.ps.g

A Survey of Hydroxyl Toward Supernova Remnants: Evidence for Extended 1720 MHz Maser Emission

We present the results of GBT observations of all four ground-state hydroxyl (OH) transitions toward 15 supernova remnants (SNRs) which show OH(1720 MHz) maser emission. This species of maser is well established as an excellent tracer of an ongoing interaction between the SNR and dense molecular material. For the majority of these objects we detect significantly higher flux densities with a single dish than has been reported with interferometric observations. We infer that spatially extended, low level maser emission is a common phenomenon that traces the large-scale interaction in maser-emitting SNRs. Additionally we use a collisional pumping model to fit the physical conditions under which OH is excited behind the SNR shock front. We find the observed OH gas associated with the SNR interaction having columns less than approximately 10^17 per square cm, temperatures of 20 to 125 K, and densities 10^5 per cubic cm.Comment: 24 pages, 23 figures, Accepted to ApJ, March 26, 2008; v2 - added Figure 6, minor clarifications to text in Sections 3 and

XMM-Newton observations of the supernova remnant IC 443: II. evidence of stellar ejecta in the inner regions

We investigate the spatial distribution of the physical and chemical properties of the hot X-ray emitting plasma of the supernova remnant IC 443, in order to get important constraints on its ionization stage, on the progenitor supernova explosion, on the age of the remnant, and its physical association with a close pulsar wind nebula. The hard X-ray thermal emission (1.4-5.0 keV) of IC 443 displays a centrally-peaked morphology, its brightness peaks being associated with hot (kT>1 keV) X-ray emitting plasma. A ring-shaped structure, characterized by high values of equivalent widths and median photon energy, encloses the PWN. Its hard X-ray emission is spectrally characterized by a collisional ionization equilibrium model, and strong emission lines of Mg, Si, and S, requiring oversolar metal abundances. Dynamically, the location of the ejecta ring suggests an SNR age of ~4,000 yr. The presence of overionized plasma in the inner regions of IC 443, addressed in previous works, is much less evident in our observations.Comment: 9 pages, 7 figures, accepted for publication in A&A. For hi-res figures, see http://www.astropa.unipa.it/Library/OAPA_preprints/aa20079123.pd

Promising pre-clinical validation of targeted radionuclide therapy using a [131I] labelled iodoquinoxaline derivative for an effective melanoma treatment

Targeted internal radionuclide therapy (TRT) would be an effective alternative to current therapies for dissemi- nated melanoma treatment. At our institution, a class of iodobenzamides has been developed as potent melanoma- seeking agents. This review described the preclinical vali- dations of a quinoxaline derivative molecule (ICF01012) as tracer for TRT application. It was selected for its high, specific and long-lasting uptake in tumour with rapid clear- ance from non-target organs providing suitable dosimetry parameters for TRT. Extended in vivo study of metabolic profiles confirmed durable tumoural concentration of the unchanged molecule form. Moreover melanin specificity of ICF01012 was determined by binding assay with syn- thetic melanin and in vivo by SIMS imaging. Then, we showed in vivo that [131I] ICF01012 treatment drastically inhibited growth of B16F0, B16Bl6 and M4Beu tumours whereas [131I] NaI or unlabelled ICF01012 treatment was without significant effect. Histological analysis showed that residual tumour cells exhibit a significant loss of aggres- siveness after treatment. This anti-tumoural effect was associated with a lengthening of the treated-mice survival time and an inhibition of lung dissemination for B16Bl6 model. Results presented here support the concept of TRT using a [131I] labelled iodoquinoxaline derivative for an effective melanoma treatment.<br /

GBT Observations of IC 443: the Nature of OH(1720 MHz) Masers and OH Absorption

We present results of spectral line observations of the ground state transitions of hydroxyl(OH) toward supernova remnant IC 443 carried out with the Green Bank Telescope. At a spatial resolution of 7.2 arcminutes we detect weak, extended OH(1720 MHz) maser emission with OH(1667/5,1612 MHz) absorption along the southern extent of the remnant, where no bright compact maser sources have been observed previously. These newly detected SNR-type masers are coincident with known molecular clumps and a ridge of shocked molecular hydrogen indicative of the SNR shock front interacting with the adjacent molecular cloud. Simultaneous observation of all four ground-state transitions of OH permits us to fit physical conditions of the shocked gas at the interaction site. A simple two-component model for the line profiles yields the physical parameters for detected regions of maser emission including excitation temperature, OH column density and filling factor. Observed line profiles suggest the shock is largely propagating toward the line-of-sight in the region of these newly identified weak masers. The implications of shock geometry and physical parameters in producing extended OH maser emission in SNRs are explored. We also present VLA radio continuum observations at 330 MHz for comparison with OH line observations of the remnant.Comment: 20 pages, 4 figures, 3 tables, submitted to Ap

The GeV to TeV connection in the environment of SNR IC 443

We have recently interpreted the source MAGIC J0616+225 as a result of delayed TeV emission of cosmic-rays diffusing from IC 443 and interacting with a cloud in the foreground of the remnant. This model was used to make predictions for future observations, especially those to be made with the Fermi satellite. Just recently, AGILE, Fermi, and VERITAS have released new results of their observations of IC 443. In this work, we compare them with the predictions of our model, exploring the GeV to TeV connection in this region of space. We use Fermi data to consider the possibility of constraining the cosmic-ray diffusion features of the environment. We analyze the cosmic-ray distributions, their interactions, and a possible detection of the SNR environment in the neutrino channel.Comment: Accepted for publication in MNRAS. 20 pages, 10 figures, 1 tabl

Ordering phenomena in quasi one-dimensional organic conductors

Low-dimensional organic conductors could establish themselves as model systems for the investigation of the physics in reduced dimensions. In the metallic state of a one-dimensional solid, Fermi-liquid theory breaks down and spin and charge degrees of freedom become separated. But the metallic phase is not stable in one dimension: as the temperature is reduced, the electronic charge and spin tend to arrange themselves in an ordered fashion due to strong correlations. The competition of the different interactions is responsible for which broken-symmetry ground state is eventually realized in a specific compound and which drives the system towards an insulating state. Here we review the various ordering phenomena and how they can be identified by optic and magnetic measurements. While the final results might look very similar in the case of a charge density wave and a charge-ordered metal, for instance, the physical cause is completely different. When density waves form, a gap opens in the density of states at the Fermi energy due to nesting of the one-dimension Fermi surface sheets. When a one-dimensional metal becomes a charge-ordered Mott insulator, on the other hand, the short-range Coulomb repulsion localizes the charge on the lattice sites and even causes certain charge patterns. We try to point out the similarities and conceptional differences of these phenomena and give an example for each of them. Particular emphasis will be put on collective phenomena which are inherently present as soon as ordering breaks the symmetry of the system.Comment: Review article Naturwissenschaften 200

A search for possible interactions between ejections from GRS 1915+105 and the surrounding interstellar medium

We have observed an extended region surrounding the first discovered galactic superluminal source GRS 1915+105, seeking evidence of interaction between the relativistic ejecta of that object and the interstellar medium. We find two radio sources axisymmetrically aligned along the sub-arcsecond relativistic ejecta of GRS 1915+105 and roughly 17' distant from it, which coincide with the luminous IRAS sources 19124+1106 and 19132+1035. We have observed these sources at centimeter (VLA), millimeter (IRAM 30m), and infrared (ISO, UKIRT, ESO/MPI 2.2m) wavelengths in both line and continuum emission. At centimeter wavelengths a non-thermal jet-like feature aligned along the outflow axis is located adjacent to the inner edge of the southern source. Strong density enhancements are found in the millimeter tracers CO and H13CO+ at the positions of both sources and some of the morphology is reminiscent of shock-like interactions; however, linewidths are narrow. At infrared wavelengths strong hydrogen recombination lines and weak lines of molecular hydrogen are observed at the southern source. We discuss these results as possible evidence of the sought-after interaction, both in terms of the regions undergoing ongoing shock-heating and in terms of them being locations of shock-induced star formation. The evidence for each of these is inconclusive. Millimeter line mapping of a portion of W 50 where the relativistic jets of the X-ray binary SS 433 interact with the interstellar medium shows roughly similar morphology as GRS 1915+105, suggesting that the phenomena observed at the IRAS sources may not be unusual for such a long distance interaction.Comment: 13 pages, 12 figures, accepted for publication in Astronomy and Astrophysic