Symmetric discrete coherent states for n qubits

We put forward a method of constructing discrete coherent states for n qubits. After establishing appropriate displacement operators, the coherent states appear as displaced versions of a fiducial vector that is fixed by imposing a number of natural symmetry requirements on its Q-function. Using these coherent states we establish a partial order in the discrete phase space, which allows us to picture some n-qubit states as apparent distributions. We also analyze correlations in terms of sums of squared Q-functions.Comment: Published in J. Phys. A. Special issue on Coherent State

HI-deficient galaxies in intermediate density environments

Observations show that spiral galaxies in galaxy clusters tend to have on average less neutral hydrogen (HI) than galaxies of the same type and size in the field. There is accumulating evidence that such HI-deficient galaxies are also relatively frequent in galaxy groups. An important question is, which mechanisms are responsible for the gas deficiency in galaxy groups. To gain a better understanding of how environment affects the gas content of galaxies, we identified a sample of six HI-deficient galaxies from the HI Parkes All Sky Survey (HIPASS) using HI-optical scaling relations. One of the galaxies is located in the outskirts of the Fornax cluster, four are in loose galaxy groups and one is in a galaxy triplet. We present new high resolution HI observations with the Australia Telescope Compact Array (ATCA) of these galaxies. We discuss the possible cause of HI-deficiency in these galaxies based on HI observations and various multi-wavelength data. We find that the galaxies have truncated HI disks, lopsided gas distribution and some show asymmetries in their stellar disks. We conclude that both ram pressure stripping and tidal interactions are important gas removal mechanisms in low density environments.Comment: Accepted to MNRAS, 17 pages, 10 figures, 7 table

Insulated Neighborhoods: Structural and Functional Units of Mammalian Gene Control

Understanding how transcriptional enhancers control over 20,000 protein-coding genes to maintain cell-type-specific gene expression programs in all human cells is a fundamental challenge in regulatory biology. Recent studies suggest that gene regulatory elements and their target genes generally occur within insulated neighborhoods, which are chromosomal loop structures formed by the interaction of two DNA sites bound by the CTCF protein and occupied by the cohesin complex. Here, we review evidence that insulated neighborhoods provide for specific enhancer-gene interactions, are essential for both normal gene activation and repression, form a chromosome scaffold that is largely preserved throughout development, and are perturbed by genetic and epigenetic factors in disease. Insulated neighborhoods are a powerful paradigm for gene control that provides new insights into development and disease.National Institutes of Health (U.S.) (Grant HG002668

H I-deficient galaxies in intermediate-density environments

Observations show that spiral galaxies in galaxy clusters tend to have on average less neutral hydrogen (H I) than galaxies of the same type and size in the field. There is accumulating evidence that such H I-deficient galaxies are also relatively frequent in galaxy groups. An important question is that which mechanisms are responsible for the gas deficiency in galaxy groups. To gain a better understanding of how environment affects the gas content of galaxies, we identified a sample of six H I-deficient galaxies from the H I Parkes All Sky Survey (HIPASS) using H I-optical scaling relations. One of the galaxies is located in the outskirts of the Fornax cluster, four are in loose galaxy groups and one is in a galaxy triplet. We present new high-resolution H I observations with the Australia Telescope Compact Array (ATCA) of these galaxies. We discuss the possible cause of H I-deficiency in the sample based on H I observations and various multi-wavelength data. We find that the galaxies have truncated H I discs, lopsided gas distribution and some show asymmetries in their stellar discs. We conclude that both ram-pressure stripping and tidal interactions are important gas removal mechanisms in low-density environments

Cross-linguistic study of vocal pathology: perceptual features of spasmodic dysphonia in French-speaking subjects

Clinical characterisation of Spasmodic Dysphonia of the adductor type (SD) in French speakers by Klap and colleagues (1993) appears to differ from that of SD in English. This perceptual analysis aims to describe the phonetic features of French SD. A video of 6 French speakers with SD supplied by Klap and colleagues was analysed for frequency of phonatory breaks, pitch breaks, harshness, creak, breathiness and falsetto voice, rate of production, and quantity of speech output. In contrast to English SD, the French speaking SD patients demonstrated no evidence pitch breaks, but phonatory breaks, harshness and breathiness were prominent features. This verifies the French authors’ (1993) clinical description. These findings suggest that phonetic properties of a specific language may affect the manifestation of pathology in neurogenic voice disorders

High-sensitivity C-reactive protein is a predictive factor of adiposity in children : results of the Identification and prevention of Dietary- and lifestyle-induced health Effects in Children and InfantS (IDEFICS) study

Background-Whereas cross-sectional studies have shown that obesity is associated with increased C-reactive protein (CRP) levels in children, little is known about the impact of low-grade inflammation on body mass changes during growth. Methods and Results-We assessed cross-sectionally and longitudinally the association of high-sensitivity (hs)-CRP levels with overweight/obesity and related cardiometabolic risk factors in the Identification and prevention of Dietary-and lifestyle-induced health Effects in Children and InfantS (IDEFICS) cohort. 16 224 children from 8 European countries (2 to 9 years) were recruited during the baseline survey (T0). After the exclusion of 7187 children because of missing hs-CRP measurements and 2421 because of drug use during the previous week, the analysis was performed on 6616 children (Boys=3347; Girls=3269; age=6.3 +/- 1.7 years). Of them, 4110 were reexamined 2 years later (T1). Anthropometric variables, blood pressure, hs-CRP, blood lipids, glucose and insulin were measured. The population at T0 was divided into 3 categories, according to the baseline hs-CRP levels. Higher hs-CRP levels were associated with significantly higher prevalence of overweight/obesity, body mass index (BMI) z-score and central adiposity indices (P values all <0.0001), and with higher blood pressure and lower HDL-cholesterol levels. Over the 2-year follow-up, higher baseline hs-CRP levels were associated with a significant increase in BMI z-score (P<0.001) and significantly higher risk of incident overweight/obesity. Conclusions-Higher hs-CRP levels are associated to higher body mass and overweight/obesity risk in a large population of European children. Children with higher baseline levels of hs-CRP had a greater increase in BMI z-score and central adiposity over time and were at higher risk of developing overweight/obesity during growth

Implementing Push-Pull Efficiently in GraphBLAS

We factor Beamer's push-pull, also known as direction-optimized breadth-first-search (DOBFS) into 3 separable optimizations, and analyze them for generalizability, asymptotic speedup, and contribution to overall speedup. We demonstrate that masking is critical for high performance and can be generalized to all graph algorithms where the sparsity pattern of the output is known a priori. We show that these graph algorithm optimizations, which together constitute DOBFS, can be neatly and separably described using linear algebra and can be expressed in the GraphBLAS linear-algebra-based framework. We provide experimental evidence that with these optimizations, a DOBFS expressed in a linear-algebra-based graph framework attains competitive performance with state-of-the-art graph frameworks on the GPU and on a multi-threaded CPU, achieving 101 GTEPS on a Scale 22 RMAT graph.Comment: 11 pages, 7 figures, International Conference on Parallel Processing (ICPP) 201