Momentum--dependent nuclear mean fields and collective flow in heavy ion collisions

We use the Boltzmann-Uehling-Uhlenbeck model to simulate the dynamical evolution of heavy ion collisions and to compare the effects of two parametrizations of the momentum--dependent nuclear mean field that have identical properties in cold nuclear matter. We compare with recent data on nuclear flow, as characterized by transverse momentum distributions and flow ($F$) variables for symmetric and asymmetric systems. We find that the precise functional dependence of the nuclear mean field on the particle momentum is important. With our approach, we also confirm that the difference between symmetric and asymmetric systems can be used to pin down the density and momentum dependence of the nuclear self consistent one--body potential, independently. All the data can be reproduced very well with a momentum--dependent interaction with compressibility K = 210 MeV.Comment: 15 pages in ReVTeX 3.0; 12 postscript figures uuencoded; McGill/94-1

Differential Transverse Flow in Central C-Ne and C-Cu Collisions at 3.7 GeV/nucleon

Differential transverse flow of protons and pions in central C-Ne and C-Cu collisions at a beam energy of 3.7 GeV/nucleon was measured as a function of transverse momentum at the SKM-200-GIBS setup of JINR. In agreement with predictions of a transversely moving thermal model, the strength of proton differential transverse flow is found to first increase gradually and then saturate with the increasing transverse momentum in both systems. While pions are preferentially emitted in the same direction of the proton transverse flow in the reaction of C-Ne, they exhibit an anti-flow to the opposote direction of the proton transverse flow in the reaction of C-Cu due to stronger shadowing effects of the heavier target in thr whole range of transverse momentum.Comment: 15 pages, 5 figure

Radial Flow in Au+Au Collisions at E=0.25-1.15 A GeV

A systematic study of energy spectra for light particles emitted at midrapidity from Au+Au collisions at E=0.25-1.15 A GeV reveals a significant non-thermal component consistent with a collective radial flow. This component is evaluated as a function of bombarding energy and event centrality. Comparisons to Quantum Molecular Dynamics (QMD) and Boltzmann-Uehling-Uhlenbeck (BUU) models are made for different equations of state.Comment: 10 pages of text and 4 figures (all ps files in a uuencoded package)

Proton and Pion Production Relative to the Reaction Plane in Au + Au Collisions at AGS Energies

Results are presented of an analysis of proton and charged pion azimuthal distributions measured with respect to the reaction plane in Au + Au collisions at a beam momentum of about 11 AGeV/c. The azimuthal anisotropy is studied as a function of particle rapidity and transverse momentum for different centralities of the collisions. The triple differential (in rapidity, transverse momentum, and azimuthal angle) distributions are reconstructed. A comparison of the results with a previous analysis of charged particle and transverse energy flow as well as with model predictions is presented.Comment: 23 pages (LaTeX), 12 figure

Excitation function of elliptic flow in Au+Au collisions and the nuclear matter equation of state

We present measurements of the excitation function of elliptic flow at midrapidity in Au+Au collisions at beam energies from 0.09 to 1.49 GeV per nucleon. For the integral flow, we discuss the interplay between collective expansion and spectator shadowing for three centrality classes. A complete excitation function of transverse momentum dependence of elliptic flow is presented for the first time in this energy range, revealing a rapid change with incident energy below 0.4 AGeV, followed by an almost perfect scaling at the higher energies. The equation of state of compressed nuclear matter is addressed through comparisons to microscopic transport model calculations.Comment: 10 pages, 4 eps figures, submitted for publication. Data files will be available at http://www.gsi.de/~fopiwww/pub

Transition from in-plane to out-of-plane azimuthal enhancement in Au+Au collisions

The incident energy at which the azimuthal distributions in semi-central heavy ion collisions change from in-plane to out-of-plane enhancement, E_tran, is studied as a function of mass of emitted particles, their transverse momentum and centrality for Au+Au collisions. The analysis is performed in a reference frame rotated with the sidewards flow angle, Theta_flow, relative to the beam axis. A systematic decrease of E_tran as function of mass of the reaction products, their transverse momentum and collision centrality is evidenced. The predictions of a microscopic transport model (IQMD) are compared with the experimental results.Comment: 32 pages, Latex, 22 eps figures, accepted for publication in Nucl. Phys.

Rapidity distribution as a probe for elliptical flow at intermediate energies

Interplay between the spectator and participant matter in heavy-ion collisions is investigated within isospin dependent quantum molecular dynamics (IQMD) model in term of rapidity distribution of light charged particles. The effect of different types and size rapidity distributions is studied in elliptical flow. The elliptical flow patterns show important role of the nearby spectator matter on the participant zone. This role is further explained on the basis of passing time of the spectator and expansion time of the participant zone. The transition from the in-plane to out-of-plane is observed only when the mid-rapidity region is included in the rapidity bin, otherwise no transition occurs. The transition energy is found to be highly sensitive towards the size of the rapidity bin, while weakly on the type of the rapidity distribution. The theoretical results are also compared with the experimental findings and are found in good agreement.Comment: 8 figure

A Toll-Like Receptor 2 Pathway Regulates the Ppargc1a/b Metabolic Co-Activators in Mice with Staphylococcal aureus Sepsis

Activation of the host antibacterial defenses by the toll-like receptors (TLR) also selectively activates energy-sensing and metabolic pathways, but the mechanisms are poorly understood. This includes the metabolic and mitochondrial biogenesis master co-activators, Ppargc1a (PGC-1α) and Ppargc1b (PGC-1β) in Staphylococcus aureus (S. aureus) sepsis. The expression of these genes in the liver is markedly attenuated inTLR2−/− mice and markedly accentuated in TLR4−/− mice compared with wild type (WT) mice. We sought to explain this difference by using specific TLR-pathway knockout mice to test the hypothesis that these co-activator genes are directly regulated through TLR2 signaling. By comparing their responses to S. aureus with WT mice, we found that MyD88-deficient and MAL-deficient mice expressed hepatic Ppargc1a and Ppargc1b normally, but that neither gene was activated in TRAM-deficient mice. Ppargc1a/b activation did not require NF-kβ, but did require an interferon response factor (IRF), because neither gene was activated in IRF-3/7 double-knockout mice in sepsis, but both were activated normally in Unc93b1-deficient (3d) mice. Nuclear IRF-7 levels in TLR2−/− and TLR4−/− mice decreased and increased respectively post-inoculation and IRF-7 DNA-binding at the Ppargc1a promoter was demonstrated by chromatin immunoprecipitation. Also, a TLR2-TLR4-TRAM native hepatic protein complex was detected by immunoprecipitation within 6 h of S. aureus inoculation that could support MyD88-independent signaling to Ppargc1a/b. Overall, these findings disclose a novel MyD88-independent pathway in S. aureus sepsis that links TLR2 and TLR4 signaling in innate immunity to Ppargc1a/b gene regulation in a critical metabolic organ, the liver, by means of TRAM, TRIF, and IRF-7