Training workshops on Enhancing National Climate Services (ENACTS)

To help farmers coping with the negative impact of climate change CORAF and ICRAF are collaborating with various partners including AGRHYMET, Climate Change Agriculture and Food Security research program (CCAFS), the University of Reading, national meteorological and hydrological Services, nationalresearch institutes and variousNGOsinmanyWestAfrican countriesto implement innovative approaches such as climate smart agriculture (CSA), climate smart village (CSV) and Participatory Integrated Climate Services for Agriculture (PICSA). Since 2015, ICRAF has implemented PICSA approach in 8 West African countries including Benin, Burkina Faso, Ghana, Guinea, Mali, Niger, Togo, and Senegal. PICSA is an innovative approach with the objective to help farmers taking adequate decisions based on current and historical climate and meteorological data specific to their localities, also considering the options of crops, livestock and farming and other relevant livelihood options for farmers. The implementation of PICSA approach requires historical climate data and forecast locally specific to the area where each farmer is living. However, it is known that in sub-Saharan zone, the meteorological network is not very dense. Many localities lack climate information data and even where it exists, the quality is often questioned. To remedy this, ENACTS (Enhancing National Climate Services) has been developed by the Institute for Research for Development and Society (IRI) to make it possible to establish a correlation between the few observed data that exist and those of satellite images, and from this correlation, extrapolate to generate data with acceptable qualities for sites where data are missing. Based at the university of Columbia, IRI collaborates with AGRHYMET for the development and scaling of the ENACTS approach in West Africa. Along the same line, ICRAF, CORAF and AGHRYMET have agreed to organize ENACTS-MERGING training that aims to build the capacity of meteorological agents so that they can benefit from the latest performances of the ENACTS approach and be able to produce historical climate data graphs useful for PICSA implementation. A total of 20 participants coming from Benin, Burkina Faso, Cote d’Ivoire, Ghana, Mali, Niger, Nigeria, and Senegal attended the training workshop in Dakar, Senegal from June 28 to July 2, 2021. Mr. Bernard Minoungou from AGRHYMET was the main facilitator of this 5 days training workshop. Dr. Rija Faniriantsoa from IRI also followed the process and supported with one presentation on Introduction to Climate Data Tools (CDT)

Mortalité néonatale au centre hospitalier universitaire de Tengandogo, Ouagadougou, Burkina Faso: une étude de cohorte retrospective: Neonatal mortality at Tengandogo University Hospital, Ouagadougou, Burkina Faso: a retrospective cohort study

Introduction: Selon l’organisation mondiale de la santé, les décès néonataux représentent 41% de la mortalité infanto-juvénile. L’Afrique subsaharienne a le taux de mortalité néonatale le plus élevé à 28‰. L’objectif de l’étude était de mesurer le taux de mortalité néonatale et d’identifier les facteurs associés au décès au Centre hospitalier universitaire de Tengandogo, Ouagadougou, Burkina Faso. Méthodes: Les nouveaux nés de 0 à 28 jours, hospitalisés entre le 1er janvier 2013 et le 31 décembre 2017 ont été inclus dans cette étude de cohorte rétrospective au service de néonatologie et de pédiatrie. Les informations ont été extraites à partir des dossiers cliniques. La survie a été estimée par la méthode de Kaplan Meier. Un modèle de Cox a permis d’identifier les facteurs associés. Résultats: Au total 641 nouveau-nés ont été inclus. Les enfants admis dès le premier jour de leur naissance représentaient 80%. La durée médiane de séjour était de 6 jours avec un intervalle interquartile de 3-12 jours. Les principaux diagnostics étaient la prématurité (36,05%), les infections néonatales (33,23%) et l’asphyxie (17,86%). Le taux de mortalité néonatale était de 22,25 pour 1000 personnes jours. Après ajustement, le poids de naissance inferieur 1500gramme (HRa = 4,13 ; IC 95% (2,58-6,67)) et la notion de réanimation à la naissance (HRa2,62 ; IC 95% [1,64-4,39)) étaient les facteurs de risque. Conclusion: Le taux de mortalité néonatale reste élevé. Le suivi prénatal, la prévention des infections, le renforcement des moyens de réanimation et la compétence des acteurs sont essentiels pour réduire ce taux. Introduction: According to the World Health Organization, neonatal deaths account for 41% of infant and child mortality. Sub-Saharan Africa has the highest neonatal mortality rate at 28‰. The objective of the study was to measure the neonatal mortality rate and identify factors associated with death at the Tengandogo University Hospital, Ouagadougou, Burkina Faso. Method: New-borns aged 0 to 28 days, hospitalised between 1 January 2013 and 31 December 2017 were included in this retrospective cohort study in the neonatology and paediatrics department. Information was extracted from clinical records. Survival was estimated by the Kaplan Meier method. A Cox model was used to identify associated factors. Results: A total of 641 new-borns were included. Children admitted on the first day of birth accounted for 80%. The median length of stay was 6 days with an interquartile range of 3-12 days. The main diagnoses were prematurity (36.05%), neonatal infections (33.23%) and asphyxia (17.86%). The neonatal mortality rate was 22.25 per 1000 person days. After adjustment, birth weight below 1500 grams (HRa = 4.13; 95% CI (2.58-6.67)) and the notion of resuscitation at birth (HRa2.62; 95% CI (1.64-4.39)) were the risk factors. Conclusion: The neonatal mortality rate remains high. Prenatal follow-up, infection prevention, strengthening of resuscitation resources and competence of actors are essential to reduce this rate

Beta-Lactamase-Producing Genes and Integrons in <em>Escherichia coli</em> from Diarrheal Children in Ouagadougou, Burkina Faso

This study aimed to determine the resistance of diarrheagenic Escherichia coli (DEC) strains to β-lactams antibiotics and to perform the molecular characterization of extended-spectrum β-lactamases (ESBLs) and integrons genes. It was carried out from August 2013 to October 2015 and involved 31 DEC strains isolated from diarrheal stools samples collected from children less than 5 years. The identification and characterization of DEC strains were done through the standard biochemical tests that were confirmed using API 20E and polymerase chain reaction (PCR). The antibiogram was realized by the disk diffusion method, then an amplification of the β-lactamase resistance genes and integrons by PCR was done. Out of the 419 E. coli, 31 isolates (7.4%) harbored the DEC virulence genes. From these DEC, 21 (67.7%) were ESBL-producing E. coli. Susceptibility to ESBL-producing E. coli showed that the majority of isolates were highly resistant to amoxicillin (77.4%), amoxicillin-clavulanic acid (77.4%), and piperacillin (64.5%). The following antibiotic resistance genes and integron were identified: blaTEM (6.5%), blaSHV (19.4%), blaOXA (38.7%), blaCTX-M (9.7%), Int1 (58.1%), and Int3 (19.4%). No class 2 integron (Int2) was characterized. Because of the high prevalence of multidrug-resistant ESBL organisms found, there is a need of stringent pediatric infection control measures

Case Report: Breast cancer revealed by a paraneoplastic cerebellar syndrome: about one case and literature review

No Abstract

Integrating GIS and remote sensing for land use/land cover mapping and groundwater potential assessment for climate-smart cocoa irrigation in Ghana

Abstract Although Ghana is a leading global cocoa producer, its production and yield have experienced declines in recent years due to various factors, including long-term climate change such as increasing temperatures and changing rainfall patterns, as well as drought events. With the increasing exposure of cocoa-producing regions to extreme weather events, the vulnerability of cocoa production is also expected to rise. Supplemental irrigation for cocoa farmers has emerged as a viable adaptation strategy to ensure a consistent water supply and enhance yield. However, understanding the potential for surface and groundwater irrigation in the cocoa-growing belt remains limited. Consequently, this study aims to provide decision-support maps for surface and groundwater irrigation potential to aid planning and investment in climate-smart cocoa irrigation. Utilizing state-of-the-art geospatial and remote sensing tools, data, and methods, alongside in-situ groundwater data, we assess the irrigation potential within Ghana's cocoa-growing areas. Our analysis identified a total area of 22,126 km2 for cocoa plantations and 125.2 km2 for surface water bodies within the cocoa-growing regions. The multi-criteria analysis (MCA) revealed that approximately 80% of the study area exhibits moderate to very high groundwater availability potential. Comparing the MCA output with existing borehole locations demonstrated a reasonable correlation, with about 80% of existing boreholes located in areas with moderate to very high potential. Boreholes in very high potential areas had the highest mean yield of 90.7 l/min, while those in low groundwater availability potential areas registered the lowest mean yield of 58.2 l/min. Our study offers a comprehensive evaluation of water storage components and their implications for cocoa irrigation in Ghana. While groundwater availability shows a generally positive trend, soil moisture and surface water have been declining, particularly in the last decade. These findings underline the need for climate-smart cocoa irrigation strategies that make use of abundant groundwater resources during deficit periods. A balanced conjunctive use of surface and groundwater resources could thus serve as a sustainable solution for maintaining cocoa production in the face of climate change

Protracted abstinence from distinct drugs of abuse shows regulation of a common gene network

International audienceAddiction is a chronic brain disorder. Prolonged abstinence from drugs of abuse involves dysphoria, high stress responsiveness and craving. The neurobiology of drug abstinence, however, is poorly understood. We previously identified a unique set of hundred mu-opioid receptor-dependent genes in the extended amygdala, a key site for hedonic and stress processing in the brain. Here we examined these candidate genes either immediately after chronic morphine, nicotine, Δ9-tetrahydrocannabinol or alcohol, or following 4 weeks of abstinence. Regulation patterns strongly differed among chronic groups. In contrast, gene regulations strikingly converged in the abstinent groups and revealed unforeseen common adaptations within a novel huntingtin-centered molecular network previously unreported in addiction research. This study demonstrates that, regardless the drug, a specific set of transcriptional regulations develops in the abstinent brain, which possibly contributes to the negative affect characterizing protracted abstinence. This transcriptional signature may represent a hallmark of drug abstinence and a unitary adaptive molecular mechanism in substance abuse disorders

Dimensions structurelles de la libération pour l'agriculture et le développement rural: Programme RuralStruc - Phase II

Rapport

Validation d’un piège cérébral chimioattractant local à base d’hydrogel « intelligent » dans un modèle murin de résection de glioblastome

National audienc

Validation d’un piège cérébral chimioattractant local à base d’hydrogel « intelligent » dans un modèle murin de résection de glioblastome

National audienc